Ethyl 1H-1,2,3-triazole-5-carboxylate
- CAS No.
- 40594-98-7
- Chemical Name:
- Ethyl 1H-1,2,3-triazole-5-carboxylate
- Synonyms
- ethyl 1H-1,2,3-triazole-4-carboxylate;ethyl 2H-triazole-4-carboxylate;Ethyl 1H-1,2,3-triazole-5-carboxylate;1H-1,2,3-Triazole-5-carboxylic acid, ethyl ester;1H-1,2,3-TRIAZOLE-4-CARBOXYLIC ACID, ETHYL ESTER;3H-[1,2,3]TRIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER;1H-1,2,3-Triazole-4-carboxylicacid,ethylester(9CI)
- CBNumber:
- CB0841995
- Molecular Formula:
- C5H7N3O2
- Molecular Weight:
- 141.13
- MDL Number:
- MFCD08669518
- MOL File:
- 40594-98-7.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P330-P332+P313-P337+P313-P362-P403+P233-P405-P501 |
| HS Code | 2933998090 |
Ethyl 1H-1,2,3-triazole-5-carboxylate price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 158977 | 1H-1,2,3-Triazole-5-carboxylic Acid Ethyl Ester | 40594-98-7 | 500mg | $425 | 2026-06-03 | Buy |
| Activate Scientific | AS39488 | Ethyl 1H-1,2,3-triazole-4-carboxylate 98% | 40594-98-7 | 1g | $74 | 2026-06-04 | Buy |
| Activate Scientific | AS39488 | Ethyl 1H-1,2,3-triazole-4-carboxylate 98% | 40594-98-7 | 5g | $219 | 2026-06-04 | Buy |
| Matrix Scientific | 089677 | Ethyl 1H-1,2,3-triazole-4-carboxylate | 40594-98-7 | 1.00g | $466 | 2026-05-18 | Buy |
| Matrix Scientific | 089677 | Ethyl 1H-1,2,3-triazole-4-carboxylate | 40594-98-7 | 5.00g | $1537 | 2026-05-18 | Buy |
Ethyl 1H-1,2,3-triazole-5-carboxylate Chemical Properties, Uses, Production
Uses
1H-1,2,3-Triazole-5-carboxylic Acid Ethyl Ester is used in the synthesis potent inhibitors of bacterial β-lactamase.
Synthesis
4648-54-8
623-47-2
40594-98-7
Ethyl propargylate and trimethylmethylsilyl azide were injected through a 2 mL loop in a Vapourtec R2+/R4 flow system equipped with three PTFE reactor coils (10 mL) and a 250 psi back pressure regulator. The flow rate was set at 0.5 mL/min and the residence time was 1.5 hours. The system was heated to 140°C. Injections were performed every 40 min and the solvent used was acetonitrile. The total mixture flowing from the reactor was collected and a total of 5 injections were performed. The collected mixtures were combined and the acetonitrile was removed under vacuum by rotary evaporator (the collection flask of the rotary evaporator was pre-filled with saturated aqueous NaHCO3 solution to quench any HN3 that might be generated). The residual solid was dissolved in ethyl acetate and the organic phase was washed with saturated brine (3 times), dried over anhydrous sodium sulfate, filtered and the solvent evaporated. The crude product was stirred with a minimal amount of ether, filtered and dried to give ethyl 1H-1,2,3-triazole-5-carboxylate (8.65 g, 81% yield) as a white solid. Mass spectrum (ESI): m/z=142.1 [M+H]+.
References
[1] Journal of Heterocyclic Chemistry, 2009, vol. 46, # 1, p. 131 - 133
[2] Patent: WO2017/89389, 2017, A1. Location in patent: Page/Page column 35
Ethyl 1H-1,2,3-triazole-5-carboxylate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Wuhan ariel chemical Co., LTD. | 18986259541 18986259541 | sales@3stc.com | China | 3830 | 58 |
| Shanghai Youd Chemical Technology Co., Ltd. | 021-37910092 15821801668 | cong44@126.com | China | 286 | 58 |
| Hangzhou Sage Chemical Co., Ltd. | +86057186818502 13588463833 | info@sagechem.com | China | 10265 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 4905 | 55 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Chongqing Xingcan Pharmaceutical Technology Co., Ltd. | 13594048950 19923294409 | xingcanyaoye@sina.com | China | 1591 | 58 |
| Mashilabs (Shanghai) Co.,Ltd. | 19916721580 | mafarm@126.com | China | 4534 | 58 |
| Cool Pharm, Ltd | 021-60455363 18019463053 | sales@coolpharm.com | China | 8455 | 58 |
| Shanghai KunRaise Chemical Technology Co., Ltd | +86-021-50935922 | China | 715 | 55 |
View Latest Price from Ethyl 1H-1,2,3-triazole-5-carboxylate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | Ethyl 1H-1,2,3-triazole-5-carboxylate
40594-98-7
|
$1.00 | 1kg | 98% | 200KG | Career Henan Chemical Co |
-
- Ethyl 1H-1,2,3-triazole-5-carboxylate
40594-98-7
- $1.00
- 98%
- Career Henan Chemical Co
