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Copper Peptide

Copper Peptide Structure
Copper Peptide structure
CAS No.
49557-75-7
Chemical Name:
Copper Peptide
Synonyms
Ahk-cu;GHK;CB0875341;Glycyl-L-Histidyl-L-Lysine;Tripeptide-1 Copper;Blue copper peptide;Cooper Peptide;GHK Cu Copper Peptide;Cu-GHK;Copper Peptide AHK-Cu
CBNumber:
CB0875341
Molecular Formula:
C14H24N6O4
Molecular Weight:
340.38
MDL Number:
MFCD00036754
MOL File:
49557-75-7.mol
MSDS File:
SDS
Last updated:2026-07-08 07:26:47
Product description Number Pack Size Price
GHK ≥95% 27168 1mg $36
GHK ≥95% 27168 5mg $120
GHK ≥95% 27168 10mg $169
GHK 27168 5mg $109
GHK 27168 10mg $153
More product size
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Copper Peptide Properties

Melting point >144°C (dec.)
Boiling point 831.0±65.0 °C(Predicted)
Density 1.324
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility Aqueous Acid (Slightly), DMSO (Slightly)
form Solid
pka 3.11±0.10(Predicted)
color Off-White
Sequence Copper gly-his-lys
Stability Hygroscopic
InChIKey MVORZMQFXBLMHM-QWRGUYRKSA-N
SMILES C(O)(=O)[C@H](CCCCN)NC(=O)[C@H](CC1N=CNC=1)NC(=O)CN
EWG's Food Scores 1
FDA UNII 39TG2H631E
UNSPSC Code 12352209

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338

Copper Peptide price More Price(71)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 27168 GHK ≥95% 49557-75-7 1mg $36 2026-04-30 Buy
Cayman Chemical 27168 GHK ≥95% 49557-75-7 5mg $120 2026-04-30 Buy
Cayman Chemical 27168 GHK ≥95% 49557-75-7 10mg $169 2026-04-30 Buy
Cayman Chemical 27168 GHK 49557-75-7 5mg $109 2024-03-01 Buy
Cayman Chemical 27168 GHK 49557-75-7 10mg $153 2024-03-01 Buy
Product number Packaging Price Buy
27168 1mg $36 Buy
27168 5mg $120 Buy
27168 10mg $169 Buy
27168 5mg $109 Buy
27168 10mg $153 Buy

Copper Peptide Chemical Properties,Uses,Production

Description

Copper peptide GHK-Cu is a naturally occurring copper complex of the tripeptide glycyl-L-histidyl-L-lysine. The tripeptide has strong affinity for copper(II) and was first isolated from human plasma. It can be found also in saliva and urine.

Uses

Copper Peptide(GHK-Cu) can be used as skin antiaging agents.

Uses

anti-wrikle

Uses

Glycyl-L-histidyl-L-lysine is a liver cell growth factor and an asynthetic hepatotrophic agent that stimulates hepatic erythropoietic factor production.

Definition

ChEBI: Gly-His-Lys is a tripeptide composed of glycine, L-histidine and L-lysine residues joined in sequence. It has a role as a metabolite, a chelator, a vulnerary and a hepatoprotective agent.

Biological Functions

When applied topically, copper peptide works as an antioxidant, promote collagen and elastin production, and soften the appearance of fine lines and wrinkles.

Pharmaceutical Applications

Glycyl-l-histidyl-l-lysine (GHK) is a tripeptide known for its high binding affinity to Cu2+ and its complex role in wound healing. The GHK–Cu(II) complex was isolated from human plasma in the 1970s and it was shown to be an activator for wound healing. GHK–Cu(II) has two main functions: as an anti-inflammatory agent to protect the tissue from oxidative damage after the injury, and as an activator for wound healing itself as it activates the tissue remodelling.
The structure of GHK is very similar to that of common drugs used to treat ulcers.
After the initial stages of wound healing are activated, such as blood coagulation and neutrophil invasion, a second stage of wound healing begins, which includes the population of GHK at the wound, which has a high affinity to Cu2+. Mast cells, which are located in the skin, secrete GHK, which accumulates Cu2+ and forms the copper complex GHK–Cu(II) and therefore increases the metal–tripeptide concentration at the wound. First, GHK–Cu(II) has an anti-inflammatory effect by protecting the tissue from oxidative damage and by suppressing local inflammatory signals (i.e. cytokine interleukin-1 (IL-1)). Second, GHK–Cu(II) is released into the blood stream and encourages the production of wound macrophages that support the wound repair by removing the damaged tissue and secreting a family of several growth factor proteins. GHK–Cu(II) also hinders fibroblast production of TGF-β-1 and therefore suppresses the scar development. The GHK–Cu(II) complex also stimulates the growth of blood vessels, neurons and elastin, and, in general, supports most processes of wound healing.

Side effects

While Copper Peptide Serum is generally safe to use, you should be aware of potential side effects that may occur. Although rare, some individuals may experience skin irritation or redness after applying the serum. This can be due to sensitivity to the ingredients or an allergic reaction. Another potential side effect of Copper Peptide Serum is increased sensitivity to sunlight. The serum can make your skin more prone to sunburn.

References

[1] MINHUA HONG . Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines[J]. Biochemical and biophysical research communications, 2025, 742: Article 151060. DOI:10.1016/j.bbrc.2024.151060.
[2] PICKART L. The human tri-peptide GHK and tissue remodeling.[J]. Journal of Biomaterials Science, Polymer Edition, 2008, 19 8: 969-988. DOI:10.1163/156856208784909435.
[3] HYE-RYUNG CHOI. Stem cell recovering effect of copper-free GHK in skin.[J]. Journal of Peptide Science, 2012, 18 11: 685-690. DOI:10.1002/psc.2455.
[4] XIAO-MING ZHOU. GHK Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice by Suppressing TGFβ1/Smad-Mediated Epithelial-to-Mesenchymal Transition.[J]. Frontiers in Pharmacology, 2017: 904. DOI:10.3389/fphar.2017.00904.

Copper Peptide synthesis

29022-11-5
71989-26-9
109425-51-6
49557-75-7
Synthesis of Copper Peptide from Fmoc-Gly-OH and Fmoc-Lys(Boc)-OH and Fmoc-His(Trt)-OH

Copper Peptide Preparation Products And Raw materials

Raw materials

Fmoc-His(Trt)-OH Fmoc-Lys(Boc)-OH Fmoc-Gly-OH

Preparation Products

Copper Peptide Suppliers

Global( 550)Suppliers
Supplier Tel Email Country ProdList Advantage
HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD 		+86-0086-13751168070 +8613751168070 sales@huarongpharma.com China 185 58
Xi'an Kono chem co., Ltd.,
029-86107037 13289246953 info@konochemical.com China 1169 58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
+86-519-85525359 +86-15995072465 sales@xuanmingchem.com China 912 58
ZhenYiBio Technology Inc
+8615309206328 alexxue@zhenyibio.com China 298 58
Anko Intermational Trade Limited
+86-18073326374 +8618073326374; sales@goodpeptides.com China 59 58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
+8618580541567 sales@zhswyy.com China 259 58
Jinan Million Pharmaceutical Co., Ltd
0531-68659554 +8613031714605 info@millionpharm.com China 184 58
Guangzhou XinPeptide International Co.,Ltd
+8618134016563 admin@xtpeptide.com China 189 58
Shaanxi Dideu Medichem Co. Ltd 		+86-29-87569262 +86-15003564040 1056@dideu.com China 3972 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3975 58
Supplier Advantage
HUARONG(GUANGDONG) PHARMACEUTICAL CO.,LTD 		58
Xi'an Kono chem co., Ltd.,
58
Changzhou Xuanming Pharmaceutical Technology Co., Ltd.
58
ZhenYiBio Technology Inc
58
Anko Intermational Trade Limited
58
Chongqing Zhihe Biopharmaceutical Co., Ltd.
58
Jinan Million Pharmaceutical Co., Ltd
58
Guangzhou XinPeptide International Co.,Ltd
58
Shaanxi Dideu Medichem Co. Ltd 		58
Shaanxi Dideu Medichem Co. Ltd 		58

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View Lastest Price from Copper Peptide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Copper Peptide pictures 2026-07-08 Copper Peptide
49557-75-7
 $1.00 1g 99% 100kg RongNa Biotechnology Co.,Ltd
Copper Peptide pictures 2026-07-08 Copper Peptide
49557-75-7
 $5.00 1Box 99.99% 20000 boxes Hebei Jiafan Trading Company Limited
AHK-CU pictures 2026-07-08 AHK-CU
49557-75-7
 $5.00 1Box 99.99% 20000 boxes Hebei Jiafan Trading Company Limited
  • Copper Peptide pictures
  • Copper Peptide
    49557-75-7
  • $5.00
  • 99.99%
  • Hebei Jiafan Trading Company Limited
  • AHK-CU pictures
  • AHK-CU
    49557-75-7
  • $5.00
  • 99.99%
  • Hebei Jiafan Trading Company Limited

Copper Peptide Spectrum

Copper Peptide(49557-75-7)1HNMR

49557-75-7(Copper Peptide)Related Search:

Myristoyl hexapeptide-4 Biotinoyl tripeptide-1 Tripeptide-1 Prezatide copper acetate N-[1-Deoxy-3,4:5,6-bis-O-(1-methylethylidene)-D-glucitol-1-yl]-N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-glutamine 2-propen-1-yl ester
Copper tripeptide GHKCu.HCl TRIPEPTIDE-1 Tripeptide-3 L-Lysyl-L-alpha-aspartyl-L-valyl-N5-(aminocarbonyl)-L-ornithine
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