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1-phenethylpiperidin-4-ol

CAS No.
3518-76-1
Chemical Name:
1-phenethylpiperidin-4-ol
Synonyms
1-(2-Phenylethyl)-4-piperidinol;1-Phenethyl-4-piperidinol;1-phenethylpiperidin-4-ol;1-(2-Phenylethyl)piperidin-4-ol;1-(2-Phenylethyl)piperidine-4-ol;4-Piperidinol,1-(2-phenylethyl)-;4-Hydroxy-1-(2-phenylethyl)piperidine;N-(2-Phenylethyl)-4-hydroxypiperidine
CBNumber:
CB0905677
Molecular Formula:
C13H19NO
Molecular Weight:
205.3
MDL Number:
MFCD00038874
MOL File:
3518-76-1.mol
MSDS File:
SDS
Last updated:2025-08-21 11:10:19

1-phenethylpiperidin-4-ol Properties

Melting point 95.5-98.5℃
Boiling point 341.9±22.0 °C(Predicted)
Density 1.064±0.06 g/cm3(Predicted)
solubility Acetonitrile: Slightly soluble
Chloroform: Soluble
Water: Slightly soluble
pka 14.87±0.20(Predicted)
FDA UNII U62RHL2Y72

SAFETY

Risk and Safety Statements

HS Code  2933399990

1-phenethylpiperidin-4-ol price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T311499 1-(2-PHENYLETHYL)-4-PIPERIDINOL AldrichCPR 3518-76-1 5MG $134 2023-01-07 Buy
Cayman Chemical 40440 4-Hydroxy-1-(2-phenylethyl)piperidine ≥98% 3518-76-1 1mg $65 2026-04-30 Buy
Cayman Chemical 40440 4-Hydroxy-1-(2-phenylethyl)piperidine ≥98% 3518-76-1 5mg $295 2026-04-30 Buy
Cayman Chemical 40440 4-Hydroxy-1-(2-phenylethyl)piperidine ≥98% 3518-76-1 10mg $558 2026-04-30 Buy
Cayman Chemical 40440 4-Hydroxy-1-(2-phenylethyl)piperidine ≥98% 3518-76-1 25mg $930 2026-04-30 Buy
Product number Packaging Price Buy
T311499 5MG $134 Buy
40440 1mg $65 Buy
40440 5mg $295 Buy
40440 10mg $558 Buy
40440 25mg $930 Buy

1-phenethylpiperidin-4-ol Chemical Properties,Uses,Production

Uses

1-Phenethyl-4-piperidinol it is used in preparation of 1-Pyrrolidinyl Indane derivatives as Histamine H3 receptor antagonists useful in treatment of diseases.

References

[1] SHANAZ M. TEJANI-BUTT . N-Substituted derivatives of 4-piperidinyl benzilate: Affinities for brain muscarinic acetylcholine receptors[J]. Life sciences, 1990, 47 10: Pages 841-848. DOI: 10.1016/0024-3205(90)90596-j
[2] O. PREZZAVENTO*. Design and Synthesis of New Bifunctional Sigma-1 Selective Ligands with Antioxidant Activity[J]. Journal of Medicinal Chemistry, 2013, 56 6: 2447-2455. DOI: 10.1021/jm3017893
[3] SHIMPEI WATANABE. In Vitro and In Vivo Metabolite Identification Studies for the New Synthetic Opioids Acetylfentanyl, Acrylfentanyl, Furanylfentanyl, and 4-Fluoro-Isobutyrylfentanyl.[J]. AAPS Journal, 2017, 19 4: 1102-1122. DOI: 10.1208/s12248-017-0070-z

1-phenethylpiperidin-4-ol Preparation Products And Raw materials

Raw materials

Preparation Products

1-phenethylpiperidin-4-ol N-(2-Phenylethyl)-4-hydroxypiperidine 1-Phenethyl-4-piperidinol 1-(2-Phenylethyl)piperidin-4-ol 1-(2-Phenylethyl)piperidine-4-ol 4-Hydroxy-1-(2-phenylethyl)piperidine 4-Piperidinol,1-(2-phenylethyl)- 1-(2-Phenylethyl)-4-piperidinol 3518-76-1