ChemicalBook >> CAS DataBase List >>1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)-

1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)-

1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- structure

CAS No.: 2563861-90-3

Chemical Name:: 1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)-

Synonyms: 1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)-

CBNumber:: CB09769094

Molecular Formula:: C41H40N10O5

Molecular Weight:: 752.82

MDL Number:

MOL File:: 2563861-90-3.mol

TDS File:: TDS

Last updated:2026-04-24 14:58:40

Request For Quotation

1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- Properties

Density	1.59±0.1 g/cm3(Predicted)
pka	10.83±0.40(Predicted)

1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- Chemical Properties, Uses, Production

Uses

PROTAC BTK Degrader-3 is a potent BTK degrader with a DC50 value of 10.9 nM of BTK degradation in Mino cells. PROTAC BTK Degrader-3 has the potential forB-cell malignancies, including chronic lymphoid malignancies research[1].

References

[1] Zhangchen, et al. Salt of compound for degrading btk, crystal form thereof, and use thereof in medicine. Patent WO2022052950A1.

1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- Preparation Products And Raw materials

Raw materials

Preparation Products

2563861-90-3 (1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)-) Related Search:

PROTAC BTK Degrader-6 (R)-1-(3-(4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)piperidin-1-yl)propan-1-one Ibrutinib Impurity 10 1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- GBD-9

Ibrutinib

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1H-Isoindole-1,3(2H)-dione, 5-[3-[4-[4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl]-1-piperidinyl][1,3'-biazetidin]-1'-yl]-2-(2,6-dioxo-3-piperidinyl)- 2563861-90-3 C41H40N10O5