ChemicalBook >> CAS DataBase List >>3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)-

3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)-

3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)- structure

CAS No.: 2642135-72-4

Chemical Name:: 3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)-

Synonyms: Pan-RAS-IN-7;3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)-

CBNumber:: CB09835258

Molecular Formula:: C59H76N8O8

Molecular Weight:: 1025.29

MDL Number:

MOL File:: 2642135-72-4.mol

Last updated:2025-04-17 18:22:24

Request For Quotation

3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)- Properties

Density	1.29±0.1 g/cm3(Predicted)
pka	9.71±0.60(Predicted)

3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)- Chemical Properties, Uses, Production

Uses

Pan-RAS-IN-7 (Compound D101) is a pan RAS inhibitor that can be used for the synthesis of ADCs. Pan-RAS-IN-7 can be utilized in cancer research[1].

References

[1] Matthew T. B, et al. Panras inhibitor antibody-drug conjugates and methods of use thereof

3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)- Preparation Products And Raw materials

Raw materials

Preparation Products

3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)- Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai Tachizaki Biomedical Research Center	18014399201	sales@chemlab-tachizaki.com	China	2934	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
Afflon Pharmaceutical (Sichuan) Co., Ltd.	17336178085	1684779048@qq.com	China	2263	58

Supplier	Advantage
Shanghai Tachizaki Biomedical Research Center	58
TargetMol Chemicals Inc.	58
Afflon Pharmaceutical (Sichuan) Co., Ltd.	58

2642135-72-4 (3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)-) Related Search:

2-Propen-1-one, 1-[(3S)-4-[(7R)-7-[6-amino-4-methyl-3-(trifluoromethyl)-2-pyridinyl]-6-chloro-8-fluoro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]-4-quinazolinyl]-3-methyl-1-piperazinyl]- 2,7-Diazaspiro[4.4]nonane-2-acetamide, α-cyclopentyl-7-[[(2R,3R)-3-cyclopropyl-1-methyl-2-aziridinyl]carbonyl]-N-[(1R,10S,12S,18S)-1-[5-(4-cyclopropyl-1-piperazinyl)-2-[(1S)-1-methoxyethyl]-3-pyridinyl]-2,7,8,10,11,12,13,16,17,18,19,21,22,23-tetradecahydro-22,22-dimethyl-13,19-dioxo-2-(2,2,2-trifluoroethyl)-15H-3,5-etheno-14,18-imino-6,10-methano-6H-pyrrolo[3,4-g][1,12,4,18]dioxadiazacyclodocosin-12-yl]-, (αS,5S)- 1,4-Oxazepin-5(2H)-one, 4-[3-[[2-[[2-ethyl-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-(trifluoromethyl)-4-pyrimidinyl]amino]propyl]tetrahydro- RMC-7977 EHT1864

RMC5127

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Pan-RAS-IN-7 3-Pyridazinecarboxylic acid, N1-[N-(2,5-anhydro-3,4-dideoxy-3-phenyl-L-threo-pentonoyl)-N-methyl-L-valyl-3-[(2S)-1-ethyl-3-(3-hydroxy-2,2-dimethylpropyl)-2-[2-[(1S)-1-methoxyethyl]-5-(4-methyl-1-piperazinyl)-3-pyridinyl]-1H-indol-5-yl]-5-hydroxy-L-phenylalanyl]hexahydro-, (3→23)-lactone, (3S)- 2642135-72-4 C59H76N8O8