ChemicalBook >> CAS DataBase List >>Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1)

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1)

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) structure

CAS No.: 1620142-65-5

Chemical Name:: Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1)

Synonyms: R-348;R348;R 348;R-932348 choline;R932348 choline,R 932348 choline;Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1)

CBNumber:: CB09928109

Molecular Formula:: C28H35FN6O5S

Molecular Weight:: 586.68

MDL Number:

MOL File:: 1620142-65-5.mol

MSDS File:: SDS

Last updated:2026-07-27 17:00:41

Request For Quotation

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) Properties

FDA UNII	02STA794M3

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) Chemical Properties, Uses, Production

Uses

R-348 (R-932348) choline is a potent and orally active JAK3 and Syk inhibitor. R-348 reduces IFN-γ, IL-6, and IL-10 expression. R-348 effectively diminishes acute cardiac allograft rejection[1].

IC 50

JAK3; IL-6; IL-10

References

[1] Deuse T, et al. Novel immunosuppression: R348, a JAK3- and Syk-inhibitor attenuates acute cardiac allograft rejection. Transplantation. 2008 Mar 27;85(6):885-92. DOI:10.1097/TP.0b013e318166acc4

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) Preparation Products And Raw materials

Raw materials

Preparation Products

Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) Suppliers

Global Suppliers ( 3)

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	29874	58
TargetMol Chemicals Inc.	13564774135	marketing@targetmol.com	United States	19950	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58

View Latest Price from Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-07-27	R-932348 choline 1620142-65-5	$1520.00-2500.00			10g	TargetMol Chemicals Inc.

R-932348 choline
1620142-65-5
$1520.00-2500.00
TargetMol Chemicals Inc.

1620142-65-5 (Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1)) Related Search:

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Ethanaminium, 2-hydroxy-N,N,N-trimethyl-, salt with N-[[5-[[5-fluoro-4-[[4-(2-propyn-1-yloxy)phenyl]amino]-2-pyrimidinyl]amino]-2-methylphenyl]sulfonyl]propanamide (1:1) R 348 R348 R-932348 choline R932348 choline,R 932348 choline R-348 1620142-65-5 C28H35FN6O5S