2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE
- CAS No.
- 117719-17-2
- Chemical Name:
- 2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE
- Synonyms
- 5-BroMo-3-Morpholinopyrazin-2-aMine;5-bromo-3-morpholin-4-ylpyrazin-2-amine;5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE;2-Pyrazinamine, 5-bromo-3-(4-morpholinyl)-
- CBNumber:
- CB11091233
- Molecular Formula:
- C8H11BrN4O
- Molecular Weight:
- 259.1
- MDL Number:
- MFCD08056165
- MOL File:
- 117719-17-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE AldrichCPR | T144347 | 10MG | $28.6 |
| 5-Bromo-3-morpholinopyrazin-2-amine 95+% | B46885 | 1g | $54 |
| 5-Bromo-3-morpholinopyrazin-2-amine 95+% | B46885 | 5g | $60 |
| 5-Bromo-3-morpholinopyrazin-2-amine 95+% | B46885 | 10g | $170 |
| 5-Bromo-3-morpholinopyrazin-2-amine 98% | AA008UZE | 1g | $24 |
2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE price More Price(36)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T144347 | 5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE AldrichCPR | 117719-17-2 | 10MG | $28.6 | 2023-06-20 | Buy |
| Synthonix | B46885 | 5-Bromo-3-morpholinopyrazin-2-amine 95+% | 117719-17-2 | 1g | $54 | 2026-05-06 | Buy |
| Synthonix | B46885 | 5-Bromo-3-morpholinopyrazin-2-amine 95+% | 117719-17-2 | 5g | $60 | 2026-05-06 | Buy |
| Synthonix | B46885 | 5-Bromo-3-morpholinopyrazin-2-amine 95+% | 117719-17-2 | 10g | $170 | 2026-05-06 | Buy |
| aablocks | AA008UZE | 5-Bromo-3-morpholinopyrazin-2-amine 98% | 117719-17-2 | 1g | $24 | 2026-05-28 | Buy |
2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Chemical Properties,Uses,Production
Synthesis
110-91-8
24241-18-7
117719-17-2
General procedure for the synthesis of 2-amino-5-bromo-3-morpholin-4-ylpyrazine from morpholine and 2-amino-3,5-dibromopyrazine: intermediate 1-01 (15 g, 59.3 mmol) was dissolved in morpholine (15 ml, 178 mmol), and the resulting solution was subjected to a Parr reactor and heated for 48 hours at 120 °C. Upon completion of the reaction, a brown solid was observed to be produced. The solid was suspended in dichloromethane (DCM) and washed twice sequentially with aqueous sodium bicarbonate (NaHCO3). The organic phase was separated, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to dryness under reduced pressure to afford the target product I-02 as a brown solid in a yield of 14.8 g in 96% yield.
References
[1] Patent: WO2011/36461, 2011, A1. Location in patent: Page/Page column 77
[2] Tetrahedron Letters, 2012, vol. 53, # 9, p. 1082 - 1084
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 1874 - 1878
[4] Patent: US2012/83492, 2012, A1. Location in patent: Page/Page column 91
[5] Molecules, 2017, vol. 22, # 2,
2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Preparation Products And Raw materials
Raw materials
Preparation Products
2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30225 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Pure Chemistry Scientific Inc. | 001-857-928-2050 or 1-888-588-9418 | sales@chemreagents.com | United States | 10186 | 62 |
| Shanghai Ennopharm Co., Ltd. | +86 (21) 6435-5022 | China | 4267 | 65 | |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8667 | 57 |
| Shanghai yirong biology science and technology co., ltd | 18049974220 | 3060526242@qq.com | China | 1000 | 60 |
| NovoChemy Ltd. | 021-31261262/ 49 (0)17662837245 | sales@novochemy.com | Germany | 6328 | 58 |
| Shanghai Balmxy Pharmaceutical Co., Ltd | 021-24206007 13764915196 | sales@balmxy.com | China | 6939 | 55 |
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