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2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE

CAS No.
117719-17-2
Chemical Name:
2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE
Synonyms
5-BroMo-3-Morpholinopyrazin-2-aMine;5-bromo-3-morpholin-4-ylpyrazin-2-amine;5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE;2-Pyrazinamine, 5-bromo-3-(4-morpholinyl)-
CBNumber:
CB11091233
Molecular Formula:
C8H11BrN4O
Molecular Weight:
259.1
MDL Number:
MFCD08056165
MOL File:
117719-17-2.mol
MSDS File:
SDS
Last updated:2026-01-13 11:09:43
Product description Number Pack Size Price
5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE AldrichCPR T144347 10MG $28.6
5-Bromo-3-morpholinopyrazin-2-amine 95+% B46885 1g $54
5-Bromo-3-morpholinopyrazin-2-amine 95+% B46885 5g $60
5-Bromo-3-morpholinopyrazin-2-amine 95+% B46885 10g $170
5-Bromo-3-morpholinopyrazin-2-amine 98% AA008UZE 1g $24

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Properties

storage temp. under inert gas (nitrogen or Argon) at 2–8 °C

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T144347 5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE AldrichCPR 117719-17-2 10MG $28.6 2023-06-20 Buy
Synthonix B46885 5-Bromo-3-morpholinopyrazin-2-amine 95+% 117719-17-2 1g $54 2026-05-06 Buy
Synthonix B46885 5-Bromo-3-morpholinopyrazin-2-amine 95+% 117719-17-2 5g $60 2026-05-06 Buy
Synthonix B46885 5-Bromo-3-morpholinopyrazin-2-amine 95+% 117719-17-2 10g $170 2026-05-06 Buy
aablocks AA008UZE 5-Bromo-3-morpholinopyrazin-2-amine 98% 117719-17-2 1g $24 2026-05-28 Buy
Product number Packaging Price Buy
T144347 10MG $28.6 Buy
B46885 1g $54 Buy
B46885 5g $60 Buy
B46885 10g $170 Buy
AA008UZE 1g $24 Buy

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Chemical Properties,Uses,Production

Synthesis

Morpholine

110-91-8

2-Amino-3,5-dibromopyrazine

24241-18-7

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE

117719-17-2

General procedure for the synthesis of 2-amino-5-bromo-3-morpholin-4-ylpyrazine from morpholine and 2-amino-3,5-dibromopyrazine: intermediate 1-01 (15 g, 59.3 mmol) was dissolved in morpholine (15 ml, 178 mmol), and the resulting solution was subjected to a Parr reactor and heated for 48 hours at 120 °C. Upon completion of the reaction, a brown solid was observed to be produced. The solid was suspended in dichloromethane (DCM) and washed twice sequentially with aqueous sodium bicarbonate (NaHCO3). The organic phase was separated, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated to dryness under reduced pressure to afford the target product I-02 as a brown solid in a yield of 14.8 g in 96% yield.

References

[1] Patent: WO2011/36461, 2011, A1. Location in patent: Page/Page column 77
[2] Tetrahedron Letters, 2012, vol. 53, # 9, p. 1082 - 1084
[3] Bioorganic and Medicinal Chemistry Letters, 2012, vol. 22, # 5, p. 1874 - 1878
[4] Patent: US2012/83492, 2012, A1. Location in patent: Page/Page column 91
[5] Molecules, 2017, vol. 22, # 2,

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Preparation Products And Raw materials

2-AMINO-5-BROMO-3-MORPHOLIN-4-YLPYRAZINE Suppliers

Global( 39)Suppliers
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Alchem Pharmtech,Inc.
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Career Henan Chemica Co
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Aladdin Scientific
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Amadis Chemical Company Limited
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Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10186 62
Shanghai Ennopharm Co., Ltd. +86 (21) 6435-5022 China 4267 65
Shanghai Sunway Pharmaceutical Technology Co., Ltd 13761987713 hxzheng@sunwaypharm.cn China 8667 57
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 1000 60
NovoChemy Ltd. 021-31261262/ 49 (0)17662837245 sales@novochemy.com Germany 6328 58
Shanghai Balmxy Pharmaceutical Co., Ltd 021-24206007 13764915196 sales@balmxy.com China 6939 55
5-bromo-3-morpholin-4-ylpyrazin-2-amine 5-BroMo-3-Morpholinopyrazin-2-aMine 2-Pyrazinamine, 5-bromo-3-(4-morpholinyl)- 5-BROMO-3-(4-MORPHOLINYL)-2-PYRAZINAMINE 117719-17-2 C8H11BrN4O