ChemicalBook >> CAS DataBase List >>CUCURBITACIN D
CUCURBITACIN D
- CAS No.
- 3877-86-9
- Chemical Name:
- CUCURBITACIN D
- Synonyms
- Cucurbit D;elatericinea;ELATERICIN A;CUCURBITACIN D;cucurbitacine(d);Cucurbitacin D-RM;20,25-tetrahydroxy-ph;CUCURBITACIN D(AS) 10mg;CUCURBITACIN D WITH HPLC;(10α,23E)-2β,16α,20,25-Tetrahydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione
- CBNumber:
- CB1119385
- Molecular Formula:
- C30H44O7
- Molecular Weight:
- 516.67
- MDL Number:
- MFCD28963759
- MOL File:
- 3877-86-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-07-16 07:06:08
| Melting point | 151.5°C |
|---|---|
| Boiling point | 521.47°C (rough estimate) |
| Density | 1.0814 (rough estimate) |
| refractive index | 1.5820 (estimate) |
| storage temp. | 4°C, protect from light |
| solubility | Soluble in ethanol and methan |
| form | powder |
| pka | 12.66±0.29(Predicted) |
| color | White |
| InChIKey | SRPHMISUTWFFKJ-VZBBWSTBNA-N |
| SMILES | [C@@]12(C)C[C@@H](O)[C@]([H])([C@](O)(C)C(=O)/C=C/C(O)(C)C)[C@@]1(C)CC(=O)[C@@]1(C)[C@]3([H])C[C@@H](C(=O)C(C)(C)C3=CCC21)O |&1:0,3,5,7,18,23,25,28,r| |
| LogP | 1.480 (est) |
| CAS DataBase Reference | 3877-86-9 |
| FDA UNII | 5I62H4ORC7 |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H300 | |||||||||
| Precautionary statements | P301+P310+P330 | |||||||||
| Hazard Codes | Xi | |||||||||
| WGK Germany | WGK 2 | |||||||||
| HS Code | 29144000 | |||||||||
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 very toxic hazardous materials |
|||||||||
| Hazard Classifications | Acute Tox. 2 Oral | |||||||||
| Toxicity | LD50 oral in rat: 8200ug/kg | |||||||||
| NFPA 704 |
|
CUCURBITACIN D price More Price(32)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHL80254 | Cucurbitacin D phyproof? Reference Substance | 3877-86-9 | 10MG | $1070 | 2026-04-30 | Buy |
| Cayman Chemical | 36172 | Cucurbitacin D ≥98% | 3877-86-9 | 1mg | $181 | 2026-04-30 | Buy |
| Cayman Chemical | 36172 | Cucurbitacin D ≥98% | 3877-86-9 | 5mg | $808 | 2026-04-30 | Buy |
| Cayman Chemical | 36172 | Cucurbitacin D ≥98% | 3877-86-9 | 10mg | $986 | 2026-04-30 | Buy |
| Biosynth | FC73908 | Cucurbitacin D | 3877-86-9 | 1mg | $250 | 2026-06-04 | Buy |
CUCURBITACIN D Chemical Properties, Uses, Production
Uses
Cucurbitacin D acts as a potential potent anti-cancer agent in various cervical cancers through induction of apopotosis.
Definition
ChEBI: A cucurbitacin in which a lanostane skeleton is multi-substituted with hydroxy, methyl and oxo substituents, with unsaturation at positions 5 and 23.
in vivo
Cucurbitacin D (1 mg/kg, intratumoral injection, three times a week for four weeks) inhibits tumor proliferation in mice[3].
| Animal Model: | Xenograft cervical cancer cell model in nude mice[3] |
| Dosage: | 1 mg/kg; three times a week; four weeks |
| Administration: | Intratumoral injection |
| Result: | Reduced tumor volume and weight, and the expression of pAKT and pSTAT3 proteins was significantly reduced. |
IC 50
HSP90
CUCURBITACIN D Preparation Products And Raw materials
Global Suppliers ( 192)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Guangdong wengjiang Chemical Reagent Co., Ltd. | 0751-2815688 13927872512 | 3007421951@qq.com | China | 9996 | 58 |
| Huzhou ZhanShu Biotechnology Co.,Ltd | 0572-8889530 18167260939 | zsubio@163.com | China | 412 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4765 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Winherb Medical Technology Co., Ltd. | 17301719108 13341702378 | winherb@126.com | China | 1245 | 58 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3984 | 66 |
| TargetMol Chemicals Inc. | 021-021-33632979 15002134094 | marketing@targetmol.com | China | 7993 | 58 |
| Cheng Du Pufeide Biotechnology Co., Ltd. | 028-82610909 13388174823 | scglp@glp-china.com | China | 1064 | 58 |
| Shanghai BeiZhuo Biotech Co., Ltd. | 021-61119791,13386096464 | bzswkf@foxmail.com | China | 3916 | 50 |
View Latest Price from CUCURBITACIN D manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-15 | Cucurbitacin D
3877-86-9
|
$68.00-413.00 | 99.10% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-08-14 | CUCURBITACIN D
3877-86-9
|
$1.00 | 1KG | 99% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2023-02-24 | Cucurbitacin D
3877-86-9
|
10mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- Cucurbitacin D
3877-86-9
- $68.00-413.00
- 99.10%
- TargetMol Chemicals Inc.
-
- CUCURBITACIN D
3877-86-9
- $1.00
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- Cucurbitacin D
3877-86-9
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
CUCURBITACIN D
ELATERICIN A
20,25-tetrahydroxy-ph
cucurbitacine(d)
elatericinea
CUCURBITACIN D WITH HPLC
(10α,23E)-2β,16α,20,25-Tetrahydroxy-9β-methyl-19-norlanosta-5,23-diene-3,11,22-trione
Cucurbit D
(9β,10α,23E)-2β,16α,20,25-Tetrahydroxy-9-methyl-19-norlanosta-5,23-diene-3,11,22-trione
17-[(3E)-1,5-Dihydroxy-1,5-dimethyl-2-oxohex-3-en-1-yl]-2,16-dihydroxy-4,4,9,14-tetramethylestr-5-ene-3,11-dione
19-Norlanosta-5,23-diene-3,11,22-trione, 2,16,20,25-tetrahydroxy-9-methyl-, (2β,9β,10α,16α,23E)-
CUCURBITACIN D(AS) 10mg
Cucurbitacin D-RM
3877-86-9
Inhibitor
