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AIDS058893

CAS No.
127882-73-9
Chemical Name:
AIDS058893
Synonyms
W-68;AIDS058893;(5R)-5,5aα,8aβ,9-Tetrahydro-9α-[4-nitrophenylamino]-5β-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one;(5R)-5β-(4-Hydroxy-3,5-dimethoxyphenyl)-9α-(4-nitrophenylamino)-5,5aα,6,8,8aβ,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6-one;(5R)-5,8,8aβ,9-Tetrahydro-5β-(4-hydroxy-3,5-dimethoxyphenyl)-9α-[(4-nitrophenyl)amino]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6(5aαH)-one;(5R,5aR,8aS,9S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-((4-nitrophenyl)amino)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one;Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[(4-nitrophenyl)amino]-, (5R,5aR,8aS,9S)-;(5R)-5β-(3,5-Dimethoxy-4-hydroxyphenyl)-7α-(hydroxymethyl)-8α-(4-nitrophenylamino)-5,6,7,8-tetrahydronaphtho[2,3-d]-1,3-dioxole-6β-carboxylic acid 6,7-lactone
CBNumber:
CB11244712
Molecular Formula:
C27H24N2O9
Molecular Weight:
520.49
MDL Number:
MOL File:
127882-73-9.mol
MSDS File:
SDS
Last updated:2026-05-11 19:39:08

AIDS058893 Properties

Melting point 206-207 °C(Solv: ethyl acetate (141-78-6))
Boiling point 751.5±60.0 °C(Predicted)
Density 1.459±0.06 g/cm3(Predicted)
pka 9.94±0.40(Predicted)
FDA UNII 0I81858VSZ

AIDS058893 Chemical Properties, Uses, Production

Uses

GL-331 is a potent anti-cancer agent. GL-331 has demonstrated more efficacious anti-cancer activity in both the in vitro and in vivo lymphoma systems[1].

References

[1] You Y. Podophyllotoxin derivatives: current synthetic approaches for new anticancer agents. Curr Pharm Des. 2005;11(13):1695-717. DOI:10.2174/1381612053764724
[2] Huang TS, et al. A novel podophyllotoxin-derived compound GL331 is more potent than its congener VP-16 in killing refractory cancer cells. Pharm Res. 1999 Jul;16(7):997-1002. DOI:10.1023/a:1018971313256

AIDS058893 Preparation Products And Raw materials

Raw materials

Preparation Products

AIDS058893 Suppliers

Global Suppliers ( 5)
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shandong Ziyi Pharmaceutical Co., Ltd. 17860786593 1181917242@qq.com China 9911 58
TargetMol Chemicals Inc. 13564774135 marketing@targetmol.com United States 19950 58

View Latest Price from AIDS058893 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
GL-331 pictures 2026-05-11 GL-331
127882-73-9
$1520.00-2500.00 10g TargetMol Chemicals Inc.
  • GL-331 pictures
  • GL-331
    127882-73-9
  • $1520.00-2500.00
  • TargetMol Chemicals Inc.
AIDS058893 (5R)-5,5aα,8aβ,9-Tetrahydro-9α-[4-nitrophenylamino]-5β-(4-hydroxy-3,5-dimethoxyphenyl)furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(8H)-one (5R)-5,8,8aβ,9-Tetrahydro-5β-(4-hydroxy-3,5-dimethoxyphenyl)-9α-[(4-nitrophenyl)amino]furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6(5aαH)-one (5R)-5β-(3,5-Dimethoxy-4-hydroxyphenyl)-7α-(hydroxymethyl)-8α-(4-nitrophenylamino)-5,6,7,8-tetrahydronaphtho[2,3-d]-1,3-dioxole-6β-carboxylic acid 6,7-lactone (5R)-5β-(4-Hydroxy-3,5-dimethoxyphenyl)-9α-(4-nitrophenylamino)-5,5aα,6,8,8aβ,9-hexahydrofuro[3',4':6,7]naphtho[2,3-d]-1,3-dioxole-6-one W-68 Furo[3',4':6,7]naphtho[2,3-d]-1,3-dioxol-6(5aH)-one, 5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-[(4-nitrophenyl)amino]-, (5R,5aR,8aS,9S)- (5R,5aR,8aS,9S)-5-(4-hydroxy-3,5-dimethoxyphenyl)-9-((4-nitrophenyl)amino)-5,8,8a,9-tetrahydrofuro[3',4':6,7]naphtho[2,3-d][1,3]dioxol-6(5aH)-one 127882-73-9