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ChemicalBook >> CAS DataBase List >>2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Structure
2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol structure
CAS No.
5521-39-1
Chemical Name:
2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol
Synonyms
AKOS BB1150;VITAS-BB TBB005536;OTAVA-BB 7020694390;2-(4-(4-Aminophenyl);1-Piperazineethanol, 4-(4-aminophenyl)-;4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline;2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol;4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline 97%
CBNumber:
CB11262901
Molecular Formula:
C12H19N3O
Molecular Weight:
221.3
MDL Number:
MFCD00702247
MOL File:
5521-39-1.mol
MSDS File:
SDS
Last updated:2026-05-27 23:05:42
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2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Properties

storage temp. Keep in dark place,Inert atmosphere,Room temperature
Appearance Brown to black Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P
HazardClass  IRRITANT
HS Code  2933599590

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR13814 4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline 97% 5521-39-1 100mg $30 2026-06-04 Buy
Apolloscientific OR13814 4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline 97% 5521-39-1 5g $559 2026-06-04 Buy
Activate Scientific AS100551 4-(4-Aminophenyl)-1-piperazineethanol 97% 5521-39-1 1g $191 2026-06-04 Buy
Activate Scientific AS100551 4-(4-Aminophenyl)-1-piperazineethanol 97% 5521-39-1 5g $737 2026-06-04 Buy
Matrix Scientific 303820 2-(4-(4-Aminophenyl)piperazin-1-yl)ethanol 5521-39-1 250.00mg $38 2026-05-19 Buy
Product number Packaging Price Buy
OR13814 100mg $30 Buy
OR13814 5g $559 Buy
AS100551 1g $191 Buy
AS100551 5g $737 Buy
303820 250.00mg $38 Buy

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Chemical Properties, Uses, Production

Synthesis

2-[4-(4-NITROPHENYL)PIPERAZINO]-1-ETHANOL

5521-38-0

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol

5521-39-1

2-[4-(4-nitrophenyl)piperazin-1-yl]ethanol (3.6 g, 14.3 mmol) was used as a starting material and dissolved in methanol (40 mL). To this solution was added palladium/carbon catalyst (700 mg) and the reaction mixture was stirred at 0 °C overnight. After completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated to afford the target product 2-[4-(4-aminophenyl)piperazin-1-yl]ethanol (2.8 g, 88% yield) as a yellow solid.

References

[1] Patent: WO2015/27222, 2015, A2. Location in patent: Paragraph 0323
[2] Patent: WO2012/59932, 2012, A1. Location in patent: Page/Page column 113
[3] Journal of Medicinal Chemistry, 2005, vol. 48, # 7, p. 2371 - 2387
[4] Patent: US2004/87575, 2004, A1
[5] Patent: US2003/13708, 2003, A1

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Preparation Products And Raw materials

Raw materials

2-[4-(4-Nitrophenyl)piperazino]-1-ethanol Methanol Activated carbon Palladium

Preparation Products

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Suppliers

Global Suppliers ( 39)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
ShangHai KenEn Chemical Technology Co., Ltd. 13120367189;18621755571 mychess007@163.com China 1994 55
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Shanghai GaoDao Pharmaceutical Co., Ltd. 021-15001867143 15001867143 1095570358@qq.com China 915 55
ShangHai Wisacheam Pharmaceutical Co., Ltd. 13817485796 tim@wisacheampharm.com China 3698 58
Wuhan Chemwish Technology Co.， Ltd 027-67849912 sales@chemwish.com China 9144 60
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Wuhan Chemwish Technology Co., Ltd 56
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
ShangHai KenEn Chemical Technology Co., Ltd. 55
Cool Pharm, Ltd 58
Shanghai GaoDao Pharmaceutical Co., Ltd. 55
ShangHai Wisacheam Pharmaceutical Co., Ltd. 58
Wuhan Chemwish Technology Co.， Ltd 60
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol Spectrum

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol(5521-39-1)1HNMR

5521-39-1 (2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol) Related Search:

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol 2-[4-(4-Nitrophenyl)piperazino]-1-ethanol 2-[4-(2-Chloro-4-nitrophenyl)piperazin-1-yl]ethanol 2-[4-(2-Fluoro-4-nitrophenyl)piperazin-1-yl]ethanol 2-[4-[2-(Methylsulfonyl)-4-nitrophenyl]piperazin-1-yl]ethanol
2-[4-(4-Amino-2-chloro-phenyl)-piperazin-1-yl]-ethanol 2-[4-(4-Nitrophenyl)piperazino]ethyl 3-chlorobenzenecarboxylate eperezolid 2-[4-(4-Amino-phenyl)-piperazin-1-yl]-ethanol dihydrochloride 1,1,1-Trifluoro-3-[4-(4-nitrophenyl)piperazino]-2-propanol
2-[4-(4-Nitrophenyl)piperazino]ethyl N-phenylcarbamate 2-[4-(4-Nitrophenyl)piperazino]ethyl N-[3-(trifluoromethyl)phenyl]carbamate 2-[4-(4-Nitrophenyl)piperazino]ethyl 4-fluorobenzenecarboxylate 4-{2-[4-(5-Nitroquinolin-8-yl)piperazin-1-yl]ethoxy}-1,2,5-oxadiazol-3-amine 2-(4-(3-[(2-Furylmethyl)amino]-4-nitrophenyl)piperazin-1-yl)ethanol
2-[4-(2,4-Dinitrophenyl)piperazin-1-yl]ethanol 1-[4-(4-Nitrophenyl)piperazino]-3-phenoxy-2-propanol 4,5-Dihydro-5-((4-(4-(dimethylamino)phenyl)-1-piperazinyl)methyl)-2-ox azolamine

1of4

2-[4-(4-Aminophenyl)piperazin-1-yl]ethan-1-ol 4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline 2-(4-(4-Aminophenyl) AKOS BB1150 OTAVA-BB 7020694390 VITAS-BB TBB005536 4-[4-(2-Hydroxyethyl)piperazin-1-yl]aniline 97% 1-Piperazineethanol, 4-(4-aminophenyl)- 5521-39-1