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ChemicalBook >> CAS DataBase List >>4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Structure
4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE structure
CAS No.
4316-98-7
Chemical Name:
4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE
Synonyms
6-Chloropyrimidine-4,5-diamine;100063;NSC 36907;4-ChloropyriMidine-5,6-diaMine;4,5-DiaMino-6-chloropyriMidine;6-Chloro-4,5-diaminopyrimidine;6-Chloro-4,5-pyrimidinediamine;5 6-DIAMINO-4-CHLOROPYRIMIDINE;4-CHLORO-5,6-DIAMINOPYRIMIDINE;4,5-Pyrimidinediamine, 6-chloro-
CBNumber:
CB1131244
Molecular Formula:
C4H5ClN4
Molecular Weight:
144.56
MDL Number:
MFCD00023270
MOL File:
4316-98-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:07:17
Product description Number Pack Size Price
6-Chloropyrimidine-4,5-diamine >98.0%(GC)(T) C3433 1g $69
4,5-Diamino-6-chloropyrimidine TRC-D416275-250MG 250mg $109
4,5-Diamino-6-chloropyrimidine TRC-D416275-2.5G 2.5g $981
6-CHLORO-4,5-DIAMINOPYRIMIDINE 97% 57676 1G $38
6-CHLORO-4,5-DIAMINOPYRIMIDINE 97% 57676 5G $95
More product size
Request For Quotation

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Properties

Melting point 252 °C (decomp)
Boiling point 336.7±37.0 °C(Predicted)
Density 1.565
Flash point 157℃
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
solubility DMSO (Sparingly), Methanol (Slightly)
form powder to crystal
pka 2.39±0.10(Predicted)
color White to Amber to Dark green
λmax 305nm(lit.)
Stability Hygroscopic
InChI InChI=1S/C4H5ClN4/c5-3-2(6)4(7)9-1-8-3/h1H,6H2,(H2,7,8,9)
InChIKey VNSFICAUILKARD-UHFFFAOYSA-N
SMILES C1=NC(Cl)=C(N)C(N)=N1
CAS DataBase Reference 4316-98-7
EPA Substance Registry System 4,5-Pyrimidinediamine, 6-chloro- (4316-98-7)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36
TSCA  TSCA listed
HS Code  29335990
NFPA 704
0
2 0

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE price More Price(59)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical C3433 6-Chloropyrimidine-4,5-diamine >98.0%(GC)(T) 4316-98-7 1g $69 2026-04-30 Buy
TRC TRC-D416275-250MG 4,5-Diamino-6-chloropyrimidine 4316-98-7 250mg $109 2026-06-03 Buy
TRC TRC-D416275-2.5G 4,5-Diamino-6-chloropyrimidine 4316-98-7 2.5g $981 2026-06-03 Buy
AstaTech 57676 6-CHLORO-4,5-DIAMINOPYRIMIDINE 97% 4316-98-7 1G $38 2026-04-30 Buy
AstaTech 57676 6-CHLORO-4,5-DIAMINOPYRIMIDINE 97% 4316-98-7 5G $95 2026-04-30 Buy
Product number Packaging Price Buy
C3433 1g $69 Buy
TRC-D416275-250MG 250mg $109 Buy
TRC-D416275-2.5G 2.5g $981 Buy
57676 1G $38 Buy
57676 5G $95 Buy

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Chemical Properties,Uses,Production

Chemical Properties

Light yellow solid

Uses

4-Amino-6-chloropyrimidin-5-ylamine is a chlorinated diaminopyrimidine used in the preparation of various bioactive choloropurine derivatives.

Synthesis

5-Amino-4,6-dichloropyrimidine

5413-85-4

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE

4316-98-7

Step 1: 4,6-Dichloropyrimidin-5-amine (1.64 g, 10 mmol) was suspended in 5 mL of concentrated hydrochloric acid. The suspension was transferred to a sealed tube, ammonia solution was added and the reaction was stirred at 100 °C overnight. Upon completion of the reaction, the solid product was collected by filtration and dried under vacuum to afford the target compound 6-chloropyrimidine-4,5-diamine as a yellow solid (1.2 g, 83% yield).LC-MS analysis showed m/z 145 ([M+H]+).

References

[1] Patent: WO2006/46023, 2006, A1. Location in patent: Page/Page column 115-116
[2] Patent: WO2008/75110, 2008, A1. Location in patent: Page/Page column 116
[3] Patent: WO2007/125315, 2007, A2. Location in patent: Page/Page column 115
[4] Patent: WO2007/125325, 2007, A1. Location in patent: Page/Page column 92-93
[5] Organic Process Research and Development, 2011, vol. 15, # 4, p. 841 - 854

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Preparation Products And Raw materials

Raw materials

Ammonium hydroxide 4,6-Dihydroxypyrimidine N,N-Diisopropylethylamine Nickel Trifluoroacetic acid
Phosphorus oxitrichloride 4,5-Diamino-6-hydroxypyrimidine 5-Amino-4,6-dichloropyrimidine

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Preparation Products

6,7-dimethyl-1H-pteridin-4-one 4-CHLORO-PTERIDINE

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Suppliers

Global( 160)Suppliers
Supplier Tel Email Country ProdList Advantage
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29766 58
CONIER CHEM AND PHARMA LIMITED 		sales@conier.com China 49906 58
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-173 9270 1263 1057@dideu.com China 3961 58
Fuxin Pharmaceutical 		+86-021-021-50872116 contact@fuxinpharm.com China 9976 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +86-189 4982 3763 sales@tnjchem.com China 34526 58
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14301 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +8619957148339 market18@leapchem.com China 24569 58
Henan Allgreen Chemical Co.,LTD 		+86-37155567971 +86-13633837469 info@allgreenchem.com China 5990 58
HANGZHOU LEAP CHEM CO., LTD. 		+86-571-87711850 +86-15355479329 market18@leapchem.com China 43303 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+86-18621343501 product@acmec-e.com China 33301 58
Supplier Advantage
career henan chemical co 		58
CONIER CHEM AND PHARMA LIMITED 		58
Shaanxi Dideu Medichem Co. Ltd 		58
Fuxin Pharmaceutical 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58
Win-Win chemical CO., Limited 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Henan Allgreen Chemical Co.,LTD 		58
HANGZHOU LEAP CHEM CO., LTD. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58

View Lastest Price from 4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE pictures 2025-04-02 4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE
4316-98-7
 1000kg 0.99 20 tons Jiangsu Liyang Kunlun Biological Technology Co., Ltd.
4-Amino-6-chloropyrimidin-5-ylamine pictures 2020-05-17 4-Amino-6-chloropyrimidin-5-ylamine
4316-98-7
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE pictures 2019-07-06 4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE
4316-98-7
 $8.00 1kg 99% 10tons Career Henan Chemical Co

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Spectrum

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE(4316-98-7)1HNMR

4316-98-7(4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE)Related Search:

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4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE 4-CHLORO-5,6-DIAMINOPYRIMIDINE 5 6-DIAMINO-4-CHLOROPYRIMIDINE 4-Amino-6-chloropyrimidin-5-ylamine ,97% 6-Chloro-4,5-pyrimidinediamine 6-Chloro-4,5-diaminopyrimidine 4,5-Pyrimidinediamine, 6-chloro- (9CI) N-(1-phenylpropan-2-yl)-4,5-dihydrooxazol-2-amine 100063 4,5-DiaMino-6-chloropyriMidine 4-ChloropyriMidine-5,6-diaMine NSC 36907 4,5-Pyrimidinediamine, 6-chloro- 6-Chloropyrimidine-4,5-diamine 4316-98-7 Heterocycle-Pyrimidine series Amines Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals PYRIMIDINE