4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Suppliers list

Company Name:	Jiangsu Liyang Kunlun Biological Technology Co., Ltd.
Tel:	+86-13813530041
Email:	z13813530041@126.com
Products Intro:	Product Name:4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE CAS:4316-98-7 Purity:0.99 Package:200kg

Company Name:	ATK CHEMICAL COMPANY LIMITED
Tel:	+undefined-21-51877795
Email:	ivan@atkchemical.com
Products Intro:	CAS:4316-98-7 Purity:98% Package:10MG;50MG;100MG,1G,5G,10G

Company Name:	career henan chemical co
Tel:	+86-0371-86658258 +8613203830695
Email:	sales@coreychem.com
Products Intro:	Product Name:4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE CAS:4316-98-7 Purity:99% Package:1kg;8USD

Company Name:	Accela ChemBio Inc.
Tel:	+1-858-6993322
Email:	info@accelachem.com
Products Intro:	Product Name:6-Chloro-4,5-pyrimidinediamine CAS:4316-98-7 Purity:>97% Package:0.25g;1g;5g;10g;25g;100g

Company Name:	Alchem Pharmtech,Inc.
Tel:	8485655694
Email:	sales@alchempharmtech.com
Products Intro:	Product Name:6-Chloro-4,5-diaminopyrimidine CAS:4316-98-7 Purity:97+% Package:1g;10g;100g;;1kg Remarks:Z-02161

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE manufacturers

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Basic information

Product Name:	4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE
Synonyms:	4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE;4-CHLORO-5,6-DIAMINOPYRIMIDINE;5 6-DIAMINO-4-CHLOROPYRIMIDINE;4-Amino-6-chloropyrimidin-5-ylamine ,97%;6-Chloro-4,5-pyrimidinediamine;6-Chloro-4,5-diaminopyrimidine;4,5-Pyrimidinediamine, 6-chloro- (9CI);N-(1-phenylpropan-2-yl)-4,5-dihydrooxazol-2-amine
CAS:	4316-98-7
MF:	C4H5ClN4
MW:	144.56
EINECS:	224-341-1
Product Categories:	Heterocycle-Pyrimidine series;Amines;Aromatics;Heterocycles;Intermediates & Fine Chemicals;Pharmaceuticals;PYRIMIDINE
Mol File:	4316-98-7.mol

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Chemical Properties

Melting point	252 °C (decomp)
Boiling point	336.7±37.0 °C(Predicted)
density	1.565
Fp	157℃
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
solubility	DMSO (Sparingly), Methanol (Slightly)
pka	2.39±0.10(Predicted)
form	powder to crystal
color	White to Amber to Dark green
λmax	305nm(lit.)
Stability:	Hygroscopic
InChI	InChI=1S/C4H5ClN4/c5-3-2(6)4(7)9-1-8-3/h1H,6H2,(H2,7,8,9)
InChIKey	VNSFICAUILKARD-UHFFFAOYSA-N
SMILES	C1=NC(Cl)=C(N)C(N)=N1
CAS DataBase Reference	4316-98-7
EPA Substance Registry System	4,5-Pyrimidinediamine, 6-chloro- (4316-98-7)

Safety Information

MSDS Information

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Usage And Synthesis

Chemical Properties	Light yellow solid
Uses	4-Amino-6-chloropyrimidin-5-ylamine is a chlorinated diaminopyrimidine used in the preparation of various bioactive choloropurine derivatives.
Synthesis	5413-85-4 4316-98-7 Step 1: 4,6-Dichloropyrimidin-5-amine (1.64 g, 10 mmol) was suspended in 5 mL of concentrated hydrochloric acid. The suspension was transferred to a sealed tube, ammonia solution was added and the reaction was stirred at 100 °C overnight. Upon completion of the reaction, the solid product was collected by filtration and dried under vacuum to afford the target compound 6-chloropyrimidine-4,5-diamine as a yellow solid (1.2 g, 83% yield).LC-MS analysis showed m/z 145 ([M+H]+).
References	[1] Patent: WO2006/46023, 2006, A1. Location in patent: Page/Page column 115-116 [2] Patent: WO2008/75110, 2008, A1. Location in patent: Page/Page column 116 [3] Patent: WO2007/125315, 2007, A2. Location in patent: Page/Page column 115 [4] Patent: WO2007/125325, 2007, A1. Location in patent: Page/Page column 92-93 [5] Organic Process Research and Development, 2011, vol. 15, # 4, p. 841 - 854

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE Preparation Products And Raw materials

Raw materials	Phosphorus oxitrichloride-->Ammonium hydroxide-->Trifluoroacetic acid-->Nickel-->N,N-Diisopropylethylamine-->4,6-Dihydroxypyrimidine-->4,5-Diamino-6-hydroxypyrimidine-->5-Amino-4,6-dichloropyrimidine
Preparation Products	6,7-dimethyl-1H-pteridin-4-one-->4-CHLORO-PTERIDINE

Tag:4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE(4316-98-7) Related Product Information

4-AMINO-6-CHLOROPYRIMIDIN-5-YLAMINE 4-CHLORO-6-HYDRAZINO-PYRIMIDIN-5-YLAMINE 6-CHLORO-5-NITROPYRIMIDIN-4-AMINE 4-Chloro-2,6-diaminopyrimidine 2,6-Diamino-4-chloropyrimidine 1-oxide 4,5-Diaminopyrimidine IFLAB-BB F2124-0139 IFLAB-BB F2124-0138 6-CHLORO-5-NITROPYRIMIDINE-2,4-DIAMINE 4-CHLORO-6-MORPHOLIN-4-YL-PYRIMIDIN-5-YLAMINE 6-CHLORO-N4,N4-DIMETHYL-PYRIMIDINE-4,5-DIAMINE IFLAB-BB F2124-0125 4-CHLORO-6-(4-METHYL-1-PIPERAZINYL)-5-NITROPYRIMIDINE N4-METHYL-6-CHLORO-5-NITROPYRIMIDIN-4-AMINE 4-CHLORO-6-PIPERIDIN-1-YL-PYRIMIDIN-5-YLAMINE N4-benzyl-6-chloropyrimidine-4,5-diamine 4-CHLORO-5-NITRO-6-(1-PYRROLIDINYL)PYRIMIDINE N-benzyl-6-chloro-5-nitro-4-pyrimidinamine