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Dihydroresveratrol

CAS No.
58436-28-5
Chemical Name:
Dihydroresveratrol
Synonyms
5-(4-Hydroxyphenethyl)benzene-1,3-diol;5-[2-(4-Hydroxyphenyl)ethyl]benzene-1,3-diol;Dihydroresveratol;Dihydroresveratrol;a, b-Dihydroresveratrol;Dihydroveratryl alcohol;3,4',5-Trihydroxybibenzyl;3,5,4'-Trihydroxybibenzyl;3,3',5-trihydroxybibenzyl;Disulfide,bis(8-bromophenyl)
CBNumber:
CB11470201
Molecular Formula:
C14H14O3
Molecular Weight:
230.26
MDL Number:
MFCD25973128
MOL File:
58436-28-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

Dihydroresveratrol Properties

Melting point 155-157°C
Boiling point 430.3±14.0 °C(Predicted)
Density 1.291±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility Soluble in DMSO (up to 40 mg/ml) or in Ethanol (up to 30 mg/ml).
pka 9.51±0.10(Predicted)
form solid
color Off-white
Stability Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 1 month.
Cosmetics Ingredients Functions ANTIOXIDANT
SKIN CONDITIONING - HUMECTANT
SKIN PROTECTING
InChI InChI=1S/C14H14O3/c15-12-5-3-10(4-6-12)1-2-11-7-13(16)9-14(17)8-11/h3-9,15-17H,1-2H2
InChIKey HITJFUSPLYBJPE-UHFFFAOYSA-N
SMILES C1(O)=CC(CCC2=CC=C(O)C=C2)=CC(O)=C1
FDA UNII CBY43AY0TT
UNSPSC Code 12352205
NACRES NA.77

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Dihydroresveratrol price More Price(47)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich SMB00945 Dihydroresveratrol ≥95% (HPLC) 58436-28-5 10 mg $126 2026-04-30 Buy
Sigma-Aldrich SMB00945 Dihydroresveratrol ≥95% (HPLC) 58436-28-5 25 mg $315 2026-04-30 Buy
Sigma-Aldrich SMB00945 Dihydroresveratrol ≥95% (HPLC) 58436-28-5 100 mg $540 2026-04-30 Buy
Cayman Chemical 19651 Dihydroresveratrol ≥98% 58436-28-5 5mg $63 2026-04-30 Buy
Cayman Chemical 19651 Dihydroresveratrol ≥98% 58436-28-5 10mg $118 2026-04-30 Buy
Product number Packaging Price Buy
SMB00945 10 mg $126 Buy
SMB00945 25 mg $315 Buy
SMB00945 100 mg $540 Buy
19651 5mg $63 Buy
19651 10mg $118 Buy

Dihydroresveratrol Chemical Properties, Uses, Production

Description

Dihydroresveratrol (58436-28-5) is a metabolite of resveratrol produced by gut microbiota.1-3Glucoronide conjugates are found in human urine after oral intake of resveratrol-containing dietary supplements.4Dihydroresveratrol glucoside is a potent melanogenesis inhibitor in B16F0 melanoma cells.5Inactive analog of resveratrol in induction of premature senescence.6

Uses

Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. Dihydroresveratrol and dihydroresveratrol monosulfate are detectable in urine. The physiological effects of dihydroresveratrol have not been investigated.

Uses

Dihydroresveratrol is a natural phytoestrogen.

Definition

ChEBI: Dihydroresveratrol is a stilbenol that is 1,1'-ethane-1,2-diyldibenzene with hydroxy groups at positions 1, 3 and 4'. It has a role as a xenobiotic metabolite and a plant metabolite.

References

[1] CARINA M. JUNG. Interaction of dietary resveratrol with animal-associated bacteria[J]. Fems Microbiology Letters, 2009, 297 2: 266-273. DOI:10.1111/j.1574-6968.2009.01691.x
[2] LISA M BODE. In vivo and in vitro metabolism of trans-resveratrol by human gut microbiota123[J]. American Journal of Clinical Nutrition, 2013, 97 2: Pages 295-309. DOI:10.3945/ajcn.112.049379
[3] VERONIKA JAROSOVA. Metabolism of Stilbenoids by Human Faecal Microbiota.[J]. Molecules, 2019, 24 6. DOI:10.3390/molecules24061155
[4] YULIA RADKO  Lars P C  Kathrine B Christensen. Semi-preparative isolation of dihydroresveratrol-3-O-β-d-glucuronide and four resveratrol conjugates from human urine after oral intake of a resveratrol-containing dietary supplement[J]. Journal of Chromatography B, 2013, 930: Pages 54-61. DOI:10.1016/j.jchromb.2013.05.002
[5] CHISATO OODE . Synthesis of dihydroresveratrol glycosides and evaluation of their activity against melanogenesis in B16F0 melanoma cells[J]. European Journal of Medicinal Chemistry, 2014, 87: Pages 862-867. DOI:10.1016/j.ejmech.2014.09.092
[6] RICHARD G A FARAGHER. Resveratrol, but not dihydroresveratrol, induces premature senescence in primary human fibroblasts.[J]. AGE, 2011, 33 4: 555-564. DOI:10.1007/s11357-010-9201-5

501-36-0
58436-28-5
Synthesis of Dihydroresveratrol from Resveratrol

Dihydroresveratrol Preparation Products And Raw materials

Raw materials

Preparation Products

Global Suppliers ( 147)
Supplier Tel Email Country ProdList Advantage
Zhengzhou Lingzhiyue Technology Co., LTD +86-0371-55074660 Lingzhiyue@aliyun.com China 4734 58
Zhuo Ruining (Shanghai) Technology Co., Ltd 18163338995 18163338995 2605578685@qq.com China 472 58
Chembest Research Laboratories Limited 021-20908456 sales@BioChemBest.com China 5996 61
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16306 64
BioBioPha Co., Ltd. 0871-65217109 y.liu@mail.biobiopha.com China 5641 65
ShangHai YuanYe Biotechnology Co., Ltd. 15026964105 shyysw007@163.com China 4998 60
Chengdu HappySyn Pharmaceutical Technology Co., Ltd. 85114309 18982182443 yangli@happysyn.com China 2297 55
Chengdu Biopurify Phytochemicals Ltd. +86-028-82633397 18982077548 cwb1@biopurify.cn China 2376 60
Shanghai Winherb Medical Technology Co., Ltd. 17301719108 13341702378 winherb@126.com China 1245 58

View Latest Price from Dihydroresveratrol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Dihydroresveratrol pictures 2026-07-27 Dihydroresveratrol
58436-28-5
$52.00-155.00 99.88% 10g TargetMol Chemicals Inc.
Dihydroresveratrol pictures 2025-06-04 Dihydroresveratrol
58436-28-5
10g 98%+ 100kgs per Month Shanghai Qyubiotech Co., Ltd.
Dihydroresveratrol pictures 2023-07-10 Dihydroresveratrol
58436-28-5
$73.55 1g 98% 1kg Jiangsu Boquan Biotechnology Co., Ltd.

Dihydroresveratrol Spectrum

Dihydroresveratrol 3,4',5-Trihydroxybibenzyl 4-[2-(3,5-Dihydroxyphenyl)ethyl]phenol Dihydroresveratol α,β-Dihydrostilbene-3,4',5-triol 5-[2-(4-hydroxyphenyl)ethyl]-1,3-benzenediol 3,5,4'-Trihydroxybibenzyl a, b-Dihydroresveratrol 3,3',5-trihydroxybibenzyl 1,3-Benzenediol, 5-[2-(4-hydroxyphenyl)ethyl]- Resveratrol Impurity 12(Dihydro Resveratrol) Disulfide,bis(8-bromophenyl) alpha,beta-Dihydroresveratrol Dihydroresveratrol, 10 mM in DMSO 5-[2-(4-Hydroxyphenyl)ethyl]benzene-1,3-diol 5-(4-Hydroxyphenethyl)benzene-1,3-diol Dihydroveratryl alcohol 58436-28-5 Phenols