3,4',5-TRIMETHOXY-TRANS-STILBENE
- CAS No.
- 22255-22-7
- Chemical Name:
- 3,4',5-TRIMETHOXY-TRANS-STILBENE
- Synonyms
- E-Resveratrol TriMethyl Ether;RP201772;RP 201772;RP-201772;TriMethoxystibene;Trimethoxystilbene;TRISMETHOXY RESVERATROL;Tri-O-methylresveratrol;Resveratrol three ether;Trimethoxy-trans-stilbene
- CBNumber:
- CB0446671
- Molecular Formula:
- C17H18O3
- Molecular Weight:
- 270.32
- MDL Number:
- MFCD02093500
- MOL File:
- 22255-22-7.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 3,4',5-Trimethoxy-trans-stilbene >98.0%(GC) | T1829 | 5g | $299 |
| trans-trismethoxy Resveratrol ≥98% | 10188 | 50mg | $41 |
| trans-trismethoxy Resveratrol ≥98% | 10188 | 100mg | $72 |
| trans-trismethoxy Resveratrol ≥98% | 10188 | 250mg | $148 |
| trans-trismethoxy Resveratrol ≥98% | 10188 | 500mg | $274 |
| More product size | |||
| Melting point | 57°C |
|---|---|
| Boiling point | 423.8±35.0 °C(Predicted) |
| Density | 1.104±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: ≥34mg/mL |
| form | powder to crystal |
| color | white to tan |
| InChI | InChI=1S/C17H18O3/c1-18-15-8-6-13(7-9-15)4-5-14-10-16(19-2)12-17(11-14)20-3/h4-12H,1-3H3/b5-4+ |
| InChIKey | GDHNBPHYVRHYCC-SNAWJCMRSA-N |
| SMILES | C1(OC)=CC(/C=C/C2=CC=C(OC)C=C2)=CC(OC)=C1 |
| CAS DataBase Reference | 22255-22-7 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H315-H318-H335-H410 | |||||||||
| Precautionary statements | P261-P264-P273-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi,N | |||||||||
| Risk Statements | 36/37/38-50/53-41-37/38 | |||||||||
| Safety Statements | 26-36/37/39-61-60-39 | |||||||||
| RIDADR | UN 3077 9 / PGIII | |||||||||
| HS Code | 2909.30.6000 | |||||||||
| NFPA 704 |
|
3,4',5-TRIMETHOXY-TRANS-STILBENE price More Price(56)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | T1829 | 3,4',5-Trimethoxy-trans-stilbene >98.0%(GC) | 22255-22-7 | 5g | $299 | 2026-04-30 | Buy |
| Cayman Chemical | 10188 | trans-trismethoxy Resveratrol ≥98% | 22255-22-7 | 50mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 10188 | trans-trismethoxy Resveratrol ≥98% | 22255-22-7 | 100mg | $72 | 2026-04-30 | Buy |
| Cayman Chemical | 10188 | trans-trismethoxy Resveratrol ≥98% | 22255-22-7 | 250mg | $148 | 2026-04-30 | Buy |
| Cayman Chemical | 10188 | trans-trismethoxy Resveratrol ≥98% | 22255-22-7 | 500mg | $274 | 2026-04-30 | Buy |
3,4',5-TRIMETHOXY-TRANS-STILBENE Chemical Properties,Uses,Production
Description
trans-trismethoxy Resveratrol is a polyketide synthase-derived stilbene originally isolated from Virola cuspidata that has diverse biological activities. It is cytotoxic to several cancer cell lines, including PC3, KB, HT-29, SW480, and HL-60 cells (IC50s =3.6, 10.2, 16.1, 54, and 2.5 μM, respectively). trans-trismethoxy Resveratrol (15 μM) inhibits TNF-α-induced activation of NF-κB in HEK293T cells in a reporter assay. It inhibits angiogenesis in zebrafish embryos when used at a concentration of 0.1 μM.
Chemical Properties
Pale Yellow Oil
Uses
A resveratrol analog with a variety of pharmacology action, including anti-cancer properties, anti-allergic activity, estrogenic activity, antiangiogenic activity, and vascular-targeting activity against microtubule-destabilization
Uses
A resveratrol analog with a variety of pharmacology action, including inst microtubule-destabilization
Uses
Phenolic compounds, particularly flavonoids, from plant sources have long been observed to have antioxidant activity with potential benefits for human health. Resveratrol is a potent phenolic antioxidant found in grapes and red wine that also has antiproliferative and anti-inflammatory activity. When the three phenolic hydroxyl groups of resveratrol are converted to methyl ethers, the inhibition of cell growth and pro-apoptotic activities of resveratrol are enhanced.
References
[1] MICHAEL B. AUSTIN Joseph P N. The Chalcone Synthase Superfamily of Type III Polyketide Synthases[J]. ChemInform, 2003, 34 17. DOI: 10.1002/chin.200317284
[2] FAHAD S ALDAWSARI Carlos A V M. 3,4’,5-trans-Trimethoxystilbene; a natural analogue of resveratrol with enhanced anticancer potency.[J]. Investigational New Drugs, 2015, 33 3: 775-786. DOI: 10.1007/s10637-015-0222-x
[3] JUSTIN J. HEYNEKAMP. Substituted trans-Stilbenes, Including Analogues of the Natural Product Resveratrol, Inhibit the Human Tumor Necrosis Factor Alpha-Induced Activation of Transcription Factor Nuclear Factor KappaB[J]. Journal of Medicinal Chemistry, 2006, 49 24: 7182-7189. DOI: 10.1021/jm060630x
[4] MIRELLA BELLERI. Antiangiogenic and vascular-targeting activity of the microtubule-destabilizing trans-resveratrol derivative 3,5,4’-trimethoxystilbene.[J]. Molecular Pharmacology, 2005, 67 5: 1451-1459. DOI: 10.1124/mol.104.009043
3,4',5-TRIMETHOXY-TRANS-STILBENE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +8615350571055 | Sibel@chuanghaibio.com | China | 8738 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21585 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29812 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 | sales@biopurify.com | China | 4616 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 | sale02@cqherb.com | CHINA | 376 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49979 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 | marketing@targetmol.com | United States | 32466 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23541 | 58 |
View Lastest Price from 3,4',5-TRIMETHOXY-TRANS-STILBENE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-04-20 | trans-Trimethoxyresveratrol
22255-22-7
|
$30.00 | 99.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-03-20 | 3,4',5-TRIMETHOXY-TRANS-STILBENE
22255-22-7
|
$10.00 | 1KG | 99% | 10 mt | Hebei Chuanghai Biotechnology Co., Ltd | |
 |
2023-02-24 | 3,4',5-Trimethoxy-trans-stilbene
22255-22-7
|
5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. |
-
- trans-Trimethoxyresveratrol
22255-22-7
- $30.00
- 99.98%
- TargetMol Chemicals Inc.
-
- 3,4',5-TRIMETHOXY-TRANS-STILBENE
22255-22-7
- $10.00
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-
- 3,4',5-Trimethoxy-trans-stilbene
22255-22-7
- $0.00
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
