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1-Isopropyl-4-piperidone

1-Isopropyl-4-piperidone Structure
1-Isopropyl-4-piperidone structure
CAS No.
5355-68-0
Chemical Name:
1-Isopropyl-4-piperidone
Synonyms
TIMTEC-BB SBB005846;isopropyl-4-piperidone;N-Isopropyl-4-piperidon;N-Isopropyl-4-piperidone;1-ISOPROPYL-4-PIPERIDONE;4-Piperidone, 1-isopropyl-;1-Isopropyl-4-piperidinone;N-Isopropyl-4-piperidinone;1-ISOPROPYL-PIPERIDIN-4-ONE;1-Isopropylpiperidine-4-one
CBNumber:
CB1166819
Molecular Formula:
C8H15NO
Molecular Weight:
141.21
MDL Number:
MFCD00038035
MOL File:
5355-68-0.mol
MSDS File:
SDS
Last updated:2025-07-24 18:12:19
Product description Number Pack Size Price
1-ISOPROPYL-4-PIPERIDONE AldrichCPR S563617 1 unit $185
1-ISOPROPYL-4-PIPERIDONE Aldrich S563617 250mg $179
1-Isopropyl-4-piperidone >97.0%(T) I0566 5g $30
1-Isopropyl-4-piperidone >97.0%(T) I0566 25g $81
1-Isopropyl-4-piperidone I779043 50mg $45
More product size
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1-Isopropyl-4-piperidone Properties

Melting point 105-105.5 °C
Boiling point 100-101 °C (27 mmHg)
Density 0.95
refractive index 1.465-1.467
Flash point 100-101°C/27mm
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 8.18±0.20(Predicted)
form clear liquid
color Colorless to Brown
BRN 107857
InChI InChI=1S/C8H15NO/c1-7(2)9-5-3-8(10)4-6-9/h7H,3-6H2,1-2H3
InChIKey CCDBCHAQIXKJCG-UHFFFAOYSA-N
SMILES N1(C(C)C)CCC(=O)CC1
CAS DataBase Reference 5355-68-0(CAS DataBase Reference)
NIST Chemistry Reference N-isopropyl-4-piperidone(5355-68-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  C,Xi
Risk Statements  34-36/37/38
Safety Statements  45-36/37/39-26-36-37
HS Code  29333990
NFPA 704
0
3 0

1-Isopropyl-4-piperidone price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S563617 1-ISOPROPYL-4-PIPERIDONE AldrichCPR 5355-68-0 1 unit $185 2025-07-31 Buy
Sigma-Aldrich S563617 1-ISOPROPYL-4-PIPERIDONE Aldrich 5355-68-0 250mg $179 2024-03-01 Buy
TCI Chemical I0566 1-Isopropyl-4-piperidone >97.0%(T) 5355-68-0 5g $30 2025-07-31 Buy
TCI Chemical I0566 1-Isopropyl-4-piperidone >97.0%(T) 5355-68-0 25g $81 2025-07-31 Buy
TRC I779043 1-Isopropyl-4-piperidone 5355-68-0 50mg $45 2021-12-16 Buy
Product number Packaging Price Buy
S563617 1 unit $185 Buy
S563617 250mg $179 Buy
I0566 5g $30 Buy
I0566 25g $81 Buy
I779043 50mg $45 Buy

1-Isopropyl-4-piperidone Chemical Properties,Uses,Production

Chemical Properties

CLEAR YELLOW TO BROWN LIQUID

Uses

Used as a pharmaceutical intermediate.

Synthesis

Preparation of 1-Isopropyl-4-piperidone: Potassium carbonate (4.2 g, 31.1 mmol) was added into a solution of isopropylamine (2.1 mL, 3.3 mmol) in ethanol (10 mL) and the resulting mixture was heated at 75 °C. A solution of 1,1-dimethyl-4-oxopiperidinium iodide (4.0 g, 15.5 mmol) in water (5 mL) was added over a period of 30 minutes. The reaction mixture was stirred 1 hour at 75 °C, and then 12 hours at room temperature. The reaction mixture was concentrated under reduced pressure. The residue was taken up with water (25 mL) and extracted with dichloromethane (25 mL). The organic layer was dried (Na2SO4) and concentrated under vacuum. a colourless oil (1.5 g, 69 %). 1H NMR (DMSO-d6, 400 MHz): δ 2.89-2.83 (m, 1 H), 2.67 (t, J=5.9 Hz, 4H), 2.29 (t, J=5.9 Hz, 4H), 0.98 (d, J=6.5 Hz, 6H). LCMS (Method C): Mass found (M+ 142.2), Rt (min): 0.63, Area (%): 99.4 (Max. Chrom.).
Preparation of 1-Isopropyl-4-piperidone

References

[1] Patent: EP2508526, 2012, A1. Location in patent: Page/Page column 45
[2] Patent: WO2012/130915, 2012, A1. Location in patent: Page/Page column 55-56

1-Isopropyl-4-piperidone Preparation Products And Raw materials

Raw materials

6-Benzylaminopurine Isopropylamine 4-Piperidinone PIPERIDINIUM, 1,1-DIMETHYL-4-OXO-, IODIDE 2-Iodopropane
Water Potassium carbonate Ethanol

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Preparation Products

4-(4-(Chlorophenyl)imino)-1-isopropyl piperidine Lorcainide N-(4-chlorophenyl)-1-isopropylpiperidin-4-amine 4-Piperidinethiol,1-(1-methylethyl)-(9CI) 4-Piperidinamine,N-methyl-1-(1-methylethyl)-(9CI)

1-Isopropyl-4-piperidone Suppliers

Global( 201)Suppliers
Supplier Tel Email Country ProdList Advantage
Anhui Yiao New Material Technology Co., Ltd 		+86-18033737140 +86-17354101231 sales1@hbganmiao.com China 227 58
Hebei Ganmiao New material Technology Co., LTD 		+86-17332992504 sales8@hbganmiao.com China 300 58
Beijing Cooperate Pharmaceutical Co.,Ltd 		010-60279497 sales01@cooperate-pharm.com CHINA 1803 55
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29830 58
Changzhou Ditong Chemical Co.,Ltd 		+86-0519-88298848 info@edengenechem.com China 2176 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49977 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
Hubei Ipure Biology Co., Ltd 		+8613367258412 ada@ipurechemical.com China 10236 58
Hefei TNJ Chemical Industry Co.,Ltd. 		+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Supplier Advantage
Anhui Yiao New Material Technology Co., Ltd 		58
Hebei Ganmiao New material Technology Co., LTD 		58
Beijing Cooperate Pharmaceutical Co.,Ltd 		55
career henan chemical co 		58
Changzhou Ditong Chemical Co.,Ltd 		58
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
Hubei Ipure Biology Co., Ltd 		58
Hefei TNJ Chemical Industry Co.,Ltd. 		58

View Lastest Price from 1-Isopropyl-4-piperidone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Isopropyl-4-piperidone pictures 2025-06-20 1-Isopropyl-4-piperidone
5355-68-0
 US $20.00-10.00 / kg 1kg 99% 200tons Hebei Yanxi Chemical Co., Ltd.
1-Isopropyl-4-piperidone pictures 2025-06-20 1-Isopropyl-4-piperidone
5355-68-0
 US $20.00-10.00 / kg 1kg 99% 200tons Hebei Yanxi Chemical Co., Ltd.
1-Isopropyl-4-piperidone pictures 2025-04-04 1-Isopropyl-4-piperidone
5355-68-0
 US $0.00-0.00 / kg 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

1-Isopropyl-4-piperidone Spectrum

1-Isopropyl-4-piperidone(5355-68-0)MS1-Isopropyl-4-piperidone(5355-68-0)1HNMR1-Isopropyl-4-piperidone(5355-68-0)13CNMR1-Isopropyl-4-piperidone(5355-68-0)IR1

5355-68-0(1-Isopropyl-4-piperidone)Related Search:

1-Methyl-4-piperidone N-Methyl-2-pyrrolidone 4-Piperidinone N,N-Diisopropylethylamine 1-Isobutyl-4-piperidone
Methyl 2-hydroxyethyl cellulose Triacetonediamine Isoproterenol 3-Methyl-2-butanone ISOPROPYLTRICHLOROSILANE
2,2'-Thiobispropane 2-Butanone oxime ISOPROPYL LAURATE Cyclopropyl methyl ketone 2,2,6,6-Tetramethyl-4-piperidinol
Isopropyl alcohol 2-Butanone 1-Phenethyl-4-piperidone

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1-ISOPROPYL-4-PIPERIDONE 1-ISOPROPYL-PIPERIDIN-4-ONE TIMTEC-BB SBB005846 1-Isopropyl-4-piperidinone 4-Piperidinone, 1-(1-methylethyl)- 4-Piperidinone,1-(1-methylethyl)- 4-Piperidone, 1-isopropyl- isopropyl-4-piperidone N-Isopropyl-4-piperidon N-Isopropyl-4-piperidone 1-(1-Methylethyl)-4-piperidinone 1-Isopropylpiperidine-4-one 1-(1'-Methylethyl)-4-piperidone,99% 1-Isopropylpiperidin-4-one 98% 1-(1''-METHYLETHYL)-4-PIPERIDONE 99% 1-Isopropyl-4-piperidone> 1-(1'-Methylethyl)-4-piperidone N-Isopropyl-4-piperidinone 5355-68-0 56355-68-0 AMINE Piperidine Heterocyclic Compounds