Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Isopropyl-4-piperidone

1-Isopropyl-4-piperidone

1-Isopropyl-4-piperidone Structure
1-Isopropyl-4-piperidone structure
CAS No.
5355-68-0
Chemical Name:
1-Isopropyl-4-piperidone
Synonyms
1-(1'-Methylethyl)-4-piperidone;TIMTEC-BB SBB005846;isopropyl-4-piperidone;N-Isopropyl-4-piperidon;N-Isopropyl-4-piperidone;1-ISOPROPYL-4-PIPERIDONE;4-Piperidone, 1-isopropyl-;1-Isopropyl-4-piperidinone;N-Isopropyl-4-piperidinone;1-ISOPROPYL-PIPERIDIN-4-ONE
CBNumber:
CB1166819
Molecular Formula:
C8H15NO
Molecular Weight:
141.21
MDL Number:
MFCD00038035
MOL File:
5355-68-0.mol
MSDS File:
SDS
Last updated:2026-05-27 23:12:20
Request For Quotation

1-Isopropyl-4-piperidone Properties

Melting point 105-105.5 °C
Boiling point 100-101 °C (27 mmHg)
Density 0.95
refractive index 1.465-1.467
Flash point 100-101°C/27mm
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 8.18±0.20(Predicted)
form clear liquid
color Colorless to Brown
BRN 107857
InChI InChI=1S/C8H15NO/c1-7(2)9-5-3-8(10)4-6-9/h7H,3-6H2,1-2H3
InChIKey CCDBCHAQIXKJCG-UHFFFAOYSA-N
SMILES N1(C(C)C)CCC(=O)CC1
CAS DataBase Reference 5355-68-0(CAS DataBase Reference)
NIST Chemistry Reference N-isopropyl-4-piperidone(5355-68-0)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  C,Xi
Risk Statements  34-36/37/38
Safety Statements  45-36/37/39-26-36-37
HS Code  29333990
NFPA 704
0
3 0

1-Isopropyl-4-piperidone price More Price(34)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S563617 1-ISOPROPYL-4-PIPERIDONE AldrichCPR 5355-68-0 1 unit $197 2026-04-30 Buy
Sigma-Aldrich S563617 1-ISOPROPYL-4-PIPERIDONE Aldrich 5355-68-0 250mg $179 2024-03-01 Buy
TCI Chemical I0566 1-Isopropyl-4-piperidone >97.0%(T) 5355-68-0 5g $31 2026-04-30 Buy
TCI Chemical I0566 1-Isopropyl-4-piperidone >97.0%(T) 5355-68-0 25g $84 2026-04-30 Buy
Apolloscientific OR9064 1-Isopropylpiperidin-4-one >98% 5355-68-0 5g $21 2026-06-04 Buy
Product number Packaging Price Buy
S563617 1 unit $197 Buy
S563617 250mg $179 Buy
I0566 5g $31 Buy
I0566 25g $84 Buy
OR9064 5g $21 Buy

1-Isopropyl-4-piperidone Chemical Properties, Uses, Production

Chemical Properties

CLEAR YELLOW TO BROWN LIQUID

Uses

Used as a pharmaceutical intermediate.

Synthesis

Preparation of 1-Isopropyl-4-piperidone: Potassium carbonate (4.2 g, 31.1 mmol) was added into a solution of isopropylamine (2.1 mL, 3.3 mmol) in ethanol (10 mL) and the resulting mixture was heated at 75 °C. A solution of 1,1-dimethyl-4-oxopiperidinium iodide (4.0 g, 15.5 mmol) in water (5 mL) was added over a period of 30 minutes. The reaction mixture was stirred 1 hour at 75 °C, and then 12 hours at room temperature. The reaction mixture was concentrated under reduced pressure. The residue was taken up with water (25 mL) and extracted with dichloromethane (25 mL). The organic layer was dried (Na2SO4) and concentrated under vacuum. a colourless oil (1.5 g, 69 %). 1H NMR (DMSO-d6, 400 MHz): δ 2.89-2.83 (m, 1 H), 2.67 (t, J=5.9 Hz, 4H), 2.29 (t, J=5.9 Hz, 4H), 0.98 (d, J=6.5 Hz, 6H). LCMS (Method C): Mass found (M+ 142.2), Rt (min): 0.63, Area (%): 99.4 (Max. Chrom.).
Preparation of 1-Isopropyl-4-piperidone

References

[1] Patent: EP2508526, 2012, A1. Location in patent: Page/Page column 45
[2] Patent: WO2012/130915, 2012, A1. Location in patent: Page/Page column 55-56

1-Isopropyl-4-piperidone Preparation Products And Raw materials

Raw materials

6-Benzylaminopurine Isopropylamine 4-Piperidinone Piperidinium, 1,1-dimethyl-4-oxo-, iodide 2-Iodopropane
Water Potassium carbonate Ethanol

1of2

Preparation Products

4-(4-(Chlorophenyl)imino)-1-isopropyl piperidine Lorcainide N-(4-chlorophenyl)-1-isopropylpiperidin-4-amine 4-Piperidinethiol,1-(1-methylethyl)-(9CI) 4-Piperidinamine,N-methyl-1-(1-methylethyl)-(9CI)

1-Isopropyl-4-piperidone Suppliers

Global Suppliers ( 205)
Supplier Tel Email Country ProdList Advantage
Shanghai Qiao Chemical Science Co., Ltd 021-58892003 info@qiaochem.com China 6065 65
Shanghai Hobor Chemical Co., Ltd 13918007836 sales@hoborchem.com China 434 60
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
TCI (Shanghai) Development Co., Ltd. 021-67121386 Sales-CN@TCIchemicals.com China 24512 81
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
JinYan Chemicals(ShangHai) Co.,Ltd. 13817811078 sales@jingyan-chemical.com China 9963 60
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Supplier Advantage
Shanghai Qiao Chemical Science Co., Ltd 65
Shanghai Hobor Chemical Co., Ltd 60
J & K SCIENTIFIC LTD. 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 62
Alfa Aesar 84
TCI (Shanghai) Development Co., Ltd. 81
Energy Chemical 61
Capot Chemical Co., Ltd 66
JinYan Chemicals(ShangHai) Co.,Ltd. 60
Jia Xing Isenchem Co.,Ltd 66

View Latest Price from 1-Isopropyl-4-piperidone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Isopropyl-4-piperidone pictures 2025-06-20 1-Isopropyl-4-piperidone
5355-68-0
 $10.00-20.00 1kg 99% 200tons Hebei Yanxi Chemical Co., Ltd.
1-Isopropyl-4-piperidone pictures 2025-06-20 1-Isopropyl-4-piperidone
5355-68-0
 $10.00-20.00 1kg 99% 200tons Hebei Yanxi Chemical Co., Ltd.
1-Isopropyl-4-piperidone pictures 2025-04-04 1-Isopropyl-4-piperidone
5355-68-0
 1kg 98% 1Ton Henan Aochuang Chemical Co.,Ltd.

1-Isopropyl-4-piperidone Spectrum

1-Isopropyl-4-piperidone(5355-68-0)MS1-Isopropyl-4-piperidone(5355-68-0)1HNMR1-Isopropyl-4-piperidone(5355-68-0)13CNMR1-Isopropyl-4-piperidone(5355-68-0)IR1

5355-68-0 (1-Isopropyl-4-piperidone) Related Search:

1-Methyl-4-piperidone N-Methyl-2-pyrrolidone 4-Piperidinone N,N-Diisopropylethylamine 1-Isobutyl-4-piperidone
Methyl 2-hydroxyethyl cellulose Triacetonediamine Isoproterenol 3-Methyl-2-butanone 2,2'-Thiobispropane
2-Butanone oxime Cyclopropyl methyl ketone 2,2,6,6-Tetramethyl-4-piperidinol Isopropyl alcohol Isopropyl laurate
Isopropyltrichlorosilane 2-Butanone 1-Phenethyl-4-piperidone

1of4

1-ISOPROPYL-4-PIPERIDONE 1-ISOPROPYL-PIPERIDIN-4-ONE TIMTEC-BB SBB005846 1-Isopropyl-4-piperidinone 4-Piperidinone, 1-(1-methylethyl)- 4-Piperidinone,1-(1-methylethyl)- 4-Piperidone, 1-isopropyl- isopropyl-4-piperidone N-Isopropyl-4-piperidon N-Isopropyl-4-piperidone 1-(1-Methylethyl)-4-piperidinone 1-Isopropylpiperidine-4-one 1-(1'-Methylethyl)-4-piperidone,99% 1-Isopropylpiperidin-4-one 98% 1-(1''-METHYLETHYL)-4-PIPERIDONE 99% 1-Isopropyl-4-piperidone> N-Isopropyl-4-piperidinone 1-(1'-Methylethyl)-4-piperidone 5355-68-0 56355-68-0 AMINE Piperidine Heterocyclic Compounds