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1-Amino-4-methylpiperazine

1-Amino-4-methylpiperazine structure

CAS No.: 6928-85-4

Chemical Name:: 1-Amino-4-methylpiperazine

Synonyms: AMPRZ;1A4MP;1-Amino-4-Methyl;TIMTEC-BB SBB004299;AMINOMETHYLPIPERAZINE;LABOTEST-BB LT00005082;1-piperazinylmethanamine;1-METHYL-4-AMINOPIERAZINE;1-AMINO-4-METHYLPIERAZINE;4-Methyl-1-piperazinamine

CBNumber:: CB1177970

Molecular Formula:: C5H13N3

Molecular Weight:: 115.18

MDL Number:: MFCD00006154

MOL File:: 6928-85-4.mol

MSDS File:: SDS

Last updated:2026-01-13 11:13:51

Product description	Number	Pack Size	Price
1-Amino-4-methylpiperazine 97%	255688	25g	$70.9
1-Amino-4-methylpiperazine >98.0%(GC)(T)	A1192	25mL	$69
1-Amino-4-methylpiperazine >98.0%(GC)(T)	A1192	500mL	$1028
1-Amino-4-methylpiperazine(>90%)	A613435	100g	$110
1-Amino-4-methylpiperazine 98%	JK200248	100g	$148
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1-Amino-4-methylpiperazine Properties

Boiling point	172-175 °C (lit.)
Density	0.957 g/mL at 25 °C (lit.)
vapor pressure	1.29hPa at 25℃
refractive index	1.4835-1.4855
Flash point	62 °C
storage temp.	Keep in dark place,Inert atmosphere,Room temperature
solubility	water: soluble
form	Viscous Solution
pka	7+-.0.42(Predicted)
color	Clear
Water Solubility	miscible
Sensitive	Air & Light Sensitive
BRN	103334
InChI	1S/C5H13N3/c1-7-2-4-8(6)5-3-7/h2-6H2,1H3
InChIKey	RJWLLQWLBMJCFD-UHFFFAOYSA-N
SMILES	CN1CCN(N)CC1
LogP	-1.61 at 25℃
CAS DataBase Reference	6928-85-4(CAS DataBase Reference)
FDA UNII	J5GBT1LFT2
NIST Chemistry Reference	1-Amino-4-methylpiperazine(6928-85-4)
UNSPSC Code	12352100
NACRES	NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P261-P264-P271-P280-P302+P352-P305+P351+P338

target organs

Respiratory system

PPE

Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter

Hazard Codes

Xi,Xn

Risk Statements

36/37/38-20/21/22

Safety Statements

24/25-36-26

RIDADR

2733

WGK Germany

HazardClass

PackingGroup

III

HS Code

29335995

Storage Class

10 - Combustible liquids

Hazard Classifications

Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

NFPA 704

	2
2		1

1-Amino-4-methylpiperazine price More Price(30)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	255688	1-Amino-4-methylpiperazine 97%	6928-85-4	25g	$70.9	2026-03-19	Buy
TCI Chemical	A1192	1-Amino-4-methylpiperazine >98.0%(GC)(T)	6928-85-4	25mL	$69	2026-03-19	Buy
TCI Chemical	A1192	1-Amino-4-methylpiperazine >98.0%(GC)(T)	6928-85-4	500mL	$1028	2026-03-19	Buy
TRC	A613435	1-Amino-4-methylpiperazine(>90%)	6928-85-4	100g	$110	2021-12-16	Buy
Frontier Specialty Chemicals	JK200248	1-Amino-4-methylpiperazine 98%	6928-85-4	100g	$148	2021-12-16	Buy

Product number	Packaging	Price	Buy
255688	25g	$70.9	Buy
A1192	25mL	$69	Buy
A1192	500mL	$1028	Buy
A613435	100g	$110	Buy
JK200248	100g	$148	Buy

1-Amino-4-methylpiperazine Chemical Properties,Uses,Production

Chemical Properties

clear colorless to light yellow liquid

Uses

1-Amino-4-methylpiperazine has been used:
in synthesis of pyrazolo-pyrazine, -pyridine derivatives and 2-[(4-methylpiperazin-1-yl)iminomethyl]phenol
as a solvating and stabilizing agent in the preparation of uniform Ag nanoparticles (<10nm)
synthesis of N-(4-Fluorobenzylidene)-4-methylpiperazin1-amine
synthesis of 4-Methyl-N-(3,4,5-trimethoxybenzylidene) piperazin-1-amine
synthesis of N-(3,4-Dichlorobenzylidene)-4- methylpiperazin-1-amine
synthesis of N-(4-(Diethylamino)benzylidene)-4- methylpiperazin-1-amine
synthesis of N-(2,5-Dimethoxybenzylidene)-4- methylpiperazin-1-amine
synthesis of 4-Methyl-N-((5-nitrofuran-2- yl)methylene)piperazin-1-amine

Application

1-Amino-4-methylpiperazine, a derivative of piperazine, is used widely as an intermediate in the synthesis of pharmaceutical agents. It is an important intermediate for Rifampicin. Rifampicin , known as rifampin, is an antibiotic used to treat a several kinds of bacterial infections such as tuberculosis, leprosy and Legionnare's disease.

Preparation

1-Amino-4-methylpiperazine is obtained from piperazine hexahydrate through the steps of methylation, hydrolysis, nitrosation and reduction.
1-Amino-4-methylpiperazine is synthesized by chlorination of methyl(diethanol)amine (I) and subsequent cyclization of the di(chloroethyl)amine (II) obtained in aqueous hydrazine.

Flammability and Explosibility

Not classified

1-Amino-4-methylpiperazine synthesis

Synthesis of 1-Amino-4-methylpiperazine from 1-methyl-4-nitrosopiperazine

1-Amino-4-methylpiperazine Preparation Products And Raw materials

Raw materials

ZINC PIPERAZINE HEXAHYDRATE 1-Methylpiperazine Water 1-Piperazinecarbaldehyde

Preparation Products

1-Amino-4-methylpiperazine Suppliers

Global( 347)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Capot Chemical Co.,Ltd.	+86-（0）57185586718; +8613336195806	sales@capot.com	China	29640	60
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21592	55
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29822	58
Shanghai Worldyang Chemical Co.,Ltd.	+86-021-56795779 +8613651600618	sales@worldyachem.com	China	967	58
Changzhou Ditong Chemical Co.,Ltd	+86-0519-88298848	info@edengenechem.com	China	2176	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
Shenzhen Excellent Biotech Co., Ltd.	13480692018	ramyan@ex-biotech.com	CHINA	954	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49977	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29794	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Shanghai Worldyang Chemical Co.,Ltd.	58
Changzhou Ditong Chemical Co.,Ltd	58
Alchem Pharmtech,Inc.	58
Shenzhen Excellent Biotech Co., Ltd.	58
CONIER CHEM AND PHARMA LIMITED	58
career henan chemical co	58

View Lastest Price from 1-Amino-4-methylpiperazine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-12-01	1-Amino-4-methylpiperazine 6928-85-4	US $0.00 / kg	1kg	99%	10000KGS	Shaanxi Dideu New Materials Co. Ltd
2025-09-25	4-Methyl-1-piperazinamine 6928-85-4	US $10.00-3.00 / kg	1kg	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2025-04-04	1-Amino-4-methylpiperazine 6928-85-4	US $0.00-0.00 / KG	1KG	98%	1ton	Henan Aochuang Chemical Co.,Ltd.

1-Amino-4-methylpiperazine
6928-85-4
US $0.00 / kg
99%
Shaanxi Dideu New Materials Co. Ltd

4-Methyl-1-piperazinamine
6928-85-4
US $10.00-3.00 / kg
99%
Henan Fengda Chemical Co., Ltd

1-Amino-4-methylpiperazine
6928-85-4
US $0.00-0.00 / KG
98%
Henan Aochuang Chemical Co.,Ltd.

1-Amino-4-methylpiperazine Spectrum

1-Amino-4-methylpiperazine(6928-85-4)MS 1-Amino-4-methylpiperazine(6928-85-4)¹HNMR 1-Amino-4-methylpiperazine(6928-85-4)¹³CNMR 1-Amino-4-methylpiperazine(6928-85-4)IR1 1-Amino-4-methylpiperazine(6928-85-4)Raman

6928-85-4(1-Amino-4-methylpiperazine)Related Search:

BUTYLAMINE HYDROCHLORIDE 1-AMINOHEPTADECANE 1-AMINONONADECANE Rifampicin 4-[(2-METHOXYETHYL)AMINO]-1-METHYLPIPERAZINE

1-AMINO-4-METHYLPIPERAZINE DIHYDROCHLORIDE MONOHYDRATE

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LABOTEST-BB LT00005082 1-METHYL-4-AMINOPIERAZINE 1-METHYL-4-AMINOPIPERAZINE 1-AMINO-4-METHYLPIERAZINE 1-AMINO-4-METHYLPIPERAZINE 4-AMINO-1-METHYLPIPERAZINE 4-methylpiperazin-1-ylamine AMPRZ TIMTEC-BB SBB004299 N-METHYL-N-AMINOPIPERAZINE 1-Piperazinamine, 4-methyl- 1-AMino-4-Methylpiperazine, 99% 25GR 1-Amino-4-methylpiperazine 97% Amino methyl piperazine Alias 4-Methyl-1-piperazinamine 4-methylpiperazin-1-amine AMINOMETHYLPIPERAZINE 1-Amino-4-Methyl 1-Amino-4-methylpiperazine ,98% 1-Methylpiperazine-4-amine 4-Methyl-1-aminopiperazine 1-Amino-4-methylpiperazine,99% 1-METHYL-4-AMINOPIPERAZINE(1-AMINO-4-METHYLPIPERAZINE) 1-piperazinylmethanamine 1-Amino-4-methylpiperazine > 1-Amino-4-methylpiperazine ISO 9001：2015 REACH 1-Amino-4-methylpiperazine (>90%) 6928-85-4 1-Amino-4-methylpiperazine 1-Amino 4-Methyl Piperazine (AMP) 1A4MP 6928-85-4 6298-85-4 C5H13N3 C5H13N2 Piperazines Heterocyclic Building Blocks Building Blocks Building Blocks Heterocyclic Building Blocks Piperazines Piperaizine Piperazine derivates