Isobutyrophenone
- CAS No.
- 611-70-1
- Chemical Name:
- Isobutyrophenone
- Synonyms
- ISOPROPYL PHENYL KETONE;2-Methylpropiophenone;isobutyrophenon;PHENYL ISOPROPYL KETONE;1-Propanone, 2-methyl-1-phenyl-;ISOBUTROPHENONE;sobutyrophenone;ISOBUTYROPHENONE;lsobutyrophenone;ISOBUTYRYLBENZENE
- CBNumber:
- CB1180914
- Molecular Formula:
- C10H12O
- Molecular Weight:
- 148.2
- MDL Number:
- MFCD00008917
- MOL File:
- 611-70-1.mol
- MSDS File:
- SDS
| Melting point | 1 °C |
|---|---|
| Boiling point | 217 °C (lit.) |
| Density | 0.988 g/mL at 25 °C (lit.) |
| vapor pressure | 1 mm Hg ( 50 °C) |
| refractive index |
n |
| Flash point | 184 °F |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Oil |
| color | Colourless |
| Water Solubility | immiscible |
| BRN | 774499 |
| Henry's Law Constant | 5.7×10-1 mol/(m3Pa) at 25℃, Zhang et al. (2010) |
| InChI | 1S/C10H12O/c1-8(2)10(11)9-6-4-3-5-7-9/h3-8H,1-2H3 |
| InChIKey | BSMGLVDZZMBWQB-UHFFFAOYSA-N |
| SMILES | CC(C)C(=O)c1ccccc1 |
| LogP | 2.73 |
| CAS DataBase Reference | 611-70-1(CAS DataBase Reference) |
| FDA UNII | 8L53972NTZ |
| NIST Chemistry Reference | Isopropyl phenyl ketone(611-70-1) |
| EPA Substance Registry System | 1-Propanone, 2-methyl-1-phenyl- (611-70-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P501 | |||||||||
| PPE | Eyeshields, Gloves, type ABEK (EN14387) respirator filter | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| TSCA | TSCA listed | |||||||||
| HS Code | 29143900 | |||||||||
| Storage Class | 10 - Combustible liquids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
Isobutyrophenone price More Price(44)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 130362 | Isobutyrophenone 97% | 611-70-1 | 25g | $51.3 | 2026-04-30 | Buy |
| Sigma-Aldrich | 130362 | Isobutyrophenone 97% | 611-70-1 | 100g | $103 | 2026-04-30 | Buy |
| TCI Chemical | I0113 | Isobutyrophenone >98.0%(GC) | 611-70-1 | 25mL | $40 | 2026-04-30 | Buy |
| TCI Chemical | I0113 | Isobutyrophenone >98.0%(GC) | 611-70-1 | 500mL | $219 | 2026-04-30 | Buy |
| ChemScene | CS-W016333 | 2-Methyl-1-phenylpropan-1-one ≥98% | 611-70-1 | 10g | $11 | 2026-06-04 | Buy |
Isobutyrophenone Chemical Properties,Uses,Production
Chemical Properties
clear colorless to very slightly yellow liquid
Uses
Isobutyrophenone is used as an internal standard in the determination of hydroxyzine hydrochloride and benzyl alcohol in injection solutions. It is also used in the preparation of alpha-hydroxyisobutyrophenone. Isobutyrophenone is employed as photosensitizer intermediate. It can react with bromoacetic acid ethyl ester to get 3-hydroxy-4-methyl-3-phenyl-valeric acid ethyl ester.
Preparation
Isobutyrophenone synthesis: Benzene underwent a Friedel–Crafts acylation with isobutyryl chloride to synthesize isobutyrophenone. The reaction was performed using excess benzene as a replacement for a typical solvent and heat to reflux (88 °C) for a period of 3 hours. Any unreacted benzene was recovered after the reaction during the distillation process. A 66 % yield of isobutyrophenone was obtained from the solar synthesis, compared to a 44 % yield from an in-lab, electrical heating analysis.
Synthesis Reference(s)
Journal of the American Chemical Society, 71, p. 1061, 1949 DOI: 10.1021/ja01171a084
The Journal of Organic Chemistry, 32, p. 404, 1967 DOI: 10.1021/jo01288a032
Tetrahedron Letters, 14, p. 2491, 1973
Flammability and Explosibility
Non flammable
Isobutyrophenone Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| Beijing Ouhe Technology Co., Ltd | 13552068683 13522913783 | 2355560935@qq.com | China | 11777 | 60 |
| Adamas Reagent, Ltd. | 400-6009262 15618770481 | yhx@titansci.com | China | 14098 | 59 |
| Shanghai Harvest Chemical Industrial Co., Ltd. | 15721252604 17321035817 | sales@harvest-chem.com | China | 2829 | 64 |
| Shanghai Hanhong Scientific Co.,Ltd. | 021-54306202 13764082696 | info@hanhongsci.com | China | 42917 | 64 |
View Lastest Price from Isobutyrophenone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-05-23 | Isobutyrophenone
611-70-1
|
$45.00-99.00 | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co Ltd | |
 |
2021-08-12 | Isobutyrophenone
611-70-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd | ||
 |
2020-01-13 | Isobutyrophenone
611-70-1
|
$1.00 | 1g | 99% | 10000KGS | Career Henan Chemical Co |
-
- Isobutyrophenone
611-70-1
- $45.00-99.00
- 99%
- Hebei Zhuanglai Chemical Trading Co Ltd
-
- Isobutyrophenone
611-70-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- Isobutyrophenone
611-70-1
- $1.00
- 99%
- Career Henan Chemical Co
