ChemicalBook >> CAS DataBase List >>8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt

8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt

CAS No.
510774-50-2
Chemical Name:
8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt
Synonyms
8-CPT-2'-O-ME CAMP NA;CAMP, 8-CPT-2'-O-ME, NA;-O-methyladenosine3’8CPT-2ME-CAMP, SODIUM SALT;-cyclicMonophosphateSodiumSalt;8-(4-Chlorophenylthio)-2’8-PCPT-2''-O-ME-CAMP SODIUM SALT;8-[(4-Chlorophenyl)thio]-2'-O-methyladenosine cyclic 3',5'-(hydrogen phosphate);8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt;8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt
CBNumber:
CB1194975
Molecular Formula:
C17H17ClN5O6PS
Molecular Weight:
485.84
MDL Number:
MFCD04974491
MOL File:
Mol file
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:01

8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt Properties

Boiling point 748.9±70.0 °C(Predicted)
Density 1.95±0.1 g/cm3(Predicted)
storage temp. Desiccate at -20°C
solubility water: 10 mg/mL
form White to off-white crystalline powder.
pka 0.92±0.60(Predicted)
Water Solubility water: 10mg/mL
UNSPSC Code 12352208

SAFETY

Risk and Safety Statements

WGK Germany  WGK 1
Storage Class 11 - Combustible Solids

8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 295627 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt Asreported 510774-50-2 1mg $496 2026-06-03 Buy
Usbiological 295627 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt Asreported 510774-50-2 2mg $672 2026-06-03 Buy
Usbiological 295627 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt Asreported 510774-50-2 5mg $1133 2026-06-03 Buy
Usbiological 295627 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt Asreported 510774-50-2 10mg $1798 2026-06-03 Buy
Usbiological 295627 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt Asreported 510774-50-2 25mg $3319 2026-06-03 Buy
Product number Packaging Price Buy
295627 1mg $496 Buy
295627 2mg $672 Buy
295627 5mg $1133 Buy
295627 10mg $1798 Buy
295627 25mg $3319 Buy

8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt Chemical Properties, Uses, Production

Uses

8-(4-Chlorophenylthio)-2''-O-methyladenosine 3'',5''-cyclic Monophosphate sodium salt is an activator of the Epac cAMP receptor. It can be used in biological study of interaction between TCL1 and Epac1 in activation of Akt kinases in plasma membranes and nuclei of 8-CPT-2-O-Me-cAMP-stimulated macrophages

Biological Activity

Selective activator of Epac, the cAMP-sensitive guanine nucleotide-exchange factor for Rap1 and Rap2. Activates Epac1 (EC 50 = 2.2 mM), but not PKA (EC 50 > 10 mM). Stimulates Epac-mediated Ca 2+ -mediated Ca 2+ release in pancreatic b-cells in vitro .

in vivo

8-CPT-2'-O-Me-cAMP (2.05μM; 1 μL; intravitreal injection) inhibits development of choroidal neovascular lesions in a laser-injury model[1].

Animal Model:Wild type (WT) C57/Bl6 mice (choroidal neovascularization (CNV) model) [1]
Dosage:2.05μM; 1 μL
Administration:Intravitreal injection
Result:Induced a slight increase in F-actin localization to the cell periphery, and reorganized cell junctions to a more linear shape, dose-dependent decreased in CNV volume, increased Rap1 activity in isolated RPE/choroids.

8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt Suppliers

Global Suppliers ( 27)
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9799 58
NewCan Biotech Limited +86-571-86912261 19975279805 sales@newcanbio.com China 9984 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44871 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Shanghai meikai technology co., ltd 021-68689288 15300790979 info@mkbio.com.cn China 9988 58
Hangzhou MolCore BioPharmatech Co.,Ltd. +86-057181025280; +8617767106207 sales@molcore.com China 49709 58
ADENOSINE 3',5'-CYCLIC MONOPHOSPHATE, 8-(4-CHLOROPHENYLTHIO)-2'-O-METHYL-, SODIUM SALT 8-PCPT-2''-O-ME-CAMP SODIUM SALT 8CPT-2ME-CAMP, SODIUM SALT 8-CPT-2'-O-ME CAMP NA CAMP, 8-CPT-2'-O-ME, NA 8-[(4-Chlorophenyl)thio]-2'-O-methyladenosine cyclic 3',5'-(hydrogen phosphate) Adenosine, 8-[(4-chlorophenyl)thio]-2'-O-methyl-, cyclic 3',5'-(hydrogen phosphate) 8-(4-Chlorophenylthio)-2&rsquo -cyclicMonophosphateSodiumSalt -O-methyladenosine3&rsquo 8-(4-Chlorophenylthio)-2'-O-methyladenosine 3',5'-cyclic monophosphate sodium salt 8-(4-Chlorophenylthio)-2',O-methyladenosine 3',5'-cyclic monophosphate sodium salt 510774-50-2 C17H16ClN5O6PSNa C17H17ClN5O6PS