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ChemicalBook >> CAS DataBase List >>(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt Structure
(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt structure
CAS No.
130464-84-5
Chemical Name:
(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt
Synonyms
BB94 sodiuM salt;BB-94 sodiuM salt;BB 94 sodiuM salt;Batimastat sodium salt;BB-94 SODIUM SALT; BB 94 SODIUM SALT; BB94 SODIUM SALT;(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt
CBNumber:
CB12128705
Molecular Formula:
C23H32N3NaO4S2
Molecular Weight:
501.64
MDL Number:
MFCD13194883
MOL File:
130464-84-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41
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(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt Properties

storage temp. Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
solubility Soluble in DMSO

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 474073 Batimastat sodium 130464-84-5 100mg $2442 2026-06-03 Buy
Biosynth FB148802 Batimastat sodium 130464-84-5 10mg $275.9 2026-06-04 Buy
Biosynth FB148802 Batimastat sodium 130464-84-5 50mg $967.5 2026-06-04 Buy
ChemScene CS-1656 Batimastat sodium salt 99.04% 130464-84-5 5mg $238 2026-06-04 Buy
ChemScene CS-1656 Batimastat sodium salt 99.04% 130464-84-5 10mg $317 2026-06-04 Buy
Product number Packaging Price Buy
474073 100mg $2442 Buy
FB148802 10mg $275.9 Buy
FB148802 50mg $967.5 Buy
CS-1656 5mg $238 Buy
CS-1656 10mg $317 Buy

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt Chemical Properties, Uses, Production

Uses

Batimastat sodium salt is a potent broad spectrum MMP inhibitor with IC50 of 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7 and MMP-3, respectively.

in vivo

Intraperitoneal administration of Batimastat (BB-94) effectively blocks growth of human ovarian carcinoma xenografts and murine melanoma metastasis and delays the growth of primary tumors in an orthotopic model of human breast cancer without cytotoxicity and without affecting mRNA levels[2]. Batimastat (BB-94) is a synthetic matrix metalloproteinase inhibitor that has shown antineoplastic and antiangiogenic activity in various tumor models. Treatment with Batimastat (60 mg/kg i.p. every other day, for a total of eight injections) concomitantly with Cisplatin (4 mg/kg i.v., every 7 days for a total of three injections) completely prevents growth and spread of both xenografts, and all animals are alive and healthy on day 200[4]. Kaplan-Meier analysis of survival (at 48 h) shows that animals treated with Batimastat (BB-94) have increased survival (95.2%) in comparison with controls (75%), and differences are almost statistically significant (p=0.064)[5]. Matrix density is analyzed in saline- or Batimastat (40 mg/kg)-pretreated animals 4 h after E2 administration, the time point at which collagen density is observed to be at its lowest after hormone treatment[6].

References

[1] Yin Z, et al. Increased MMPs expression and decreased contraction in the rat myometrium during pregnancy and in response to prolonged stretch and sex hormones. Am J Physiol Endocrinol Metab. 2012 Jul 1;303(1):E55-70. DOI:10.1152/ajpendo.00553.2011
[2] Botos I, et al. Batimastat, a potent matrix mealloproteinase inhibitor, exhibits an unexpected mode of binding. Proc Natl Acad Sci U S A. 1996 Apr 2;93(7):2749-54. DOI:10.1073/pnas.93.7.2749
[3] Hansen HP, et al. Inhibition of metalloproteinases enhances the internalization of anti-CD30 antibody Ki-3 and the cytotoxic activity of Ki-3 immunotoxin. Int J Cancer. 2002 Mar 10;98(2):210-5. DOI:10.1002/ijc.10182
[4] Giavazzi R, et al. Batimastat, a synthetic inhibitor of matrix metalloproteinases, potentiates the antitumor activity of cisplatin in ovarian carcinoma xenografts. Clin Cancer Res. 1998 Apr;4(4):985-92. PMID:9563894
[5] Ricci S, et al. Inhibition of matrix metalloproteinases attenuates brain damage in experimental meningococcal meningitis. BMC Infect Dis. 2014 Dec 31;14:726. DOI:10.1186/s12879-014-0726-6
[6] Russo LA, et al. Regulated expression of matrix metalloproteinases, inflammatory mediators, and endometrial matrix remodeling by 17beta-estradiol in the immature rat uterus. Reprod Biol Endocrinol. 2009 Nov 4;7:124. DOI:10.1186/1477-7827-7-124

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt Preparation Products And Raw materials

Raw materials

Preparation Products

(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt Suppliers

Global Suppliers ( 26)
Supplier Tel Email Country ProdList Advantage
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
AdooQ BioScience, LLC +1 (866) 930-6790 info@adooq.com United States 2774 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 028-81700200 18116577057 3003855609@qq.com China 7717 56
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2374 58
SPIRO PHARMA eric_feng1954@126.com China 9239 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Amadis Chemical Company Limited 571-89925085 sales@amadischem.com China 131885 58
Musechem +1-800-259-7612 info@musechem.com United States 4648 60
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Supplier Advantage
MedChemexpress LLC 58
AdooQ BioScience, LLC 58
Sichuan Wei Keqi Biological Technology Co., Ltd. 56
LETOPHARM LIMITED 58
SPIRO PHARMA 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Amadis Chemical Company Limited 58
Musechem 60
BOC Sciences 58
TargetMol Chemicals Inc. 58

View Latest Price from (2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Batimastat sodium salt pictures 2026-07-27 Batimastat sodium salt
130464-84-5
 $1520.00 10g TargetMol Chemicals Inc.
Batimastat sodium salt pictures 2026-07-27 Batimastat sodium salt
130464-84-5
 $1520.00 10g TargetMol Chemicals Inc.
Batimastat sodium salt pictures 2025-08-22 Batimastat sodium salt
130464-84-5
 $1520.00 10g TargetMol Chemicals Inc.

130464-84-5 ((2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt) Related Search:

8-Amino-1-naphthol-3,6-disulfonic acid monosodium salt monohydrate Sodium hydroxide Sodium benzoate Sodium acetate Diisobutylcarbinol
Sodium chloride Sodium bicarbonate Diclofenac sodium Sodium chlorite Diisobutylaluminium hydride
Sodium sulfate Tris(hydroxymethyl)aminomethane Chlorophosphonazo III 4-Methyl-2-pentanone 3,4'-Diaminodiphenylmethane
8-Chloroadenosine-3',5'-cyclic monophosphorothioate, RP-isomer sodium salt 2-chloro-6-fluoro-benzoate (2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt

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(2S,3R)-N-Hydroxy-N'-[(2S)-1-methylamino-1-oxo-3-phenylpropan-2-yl]-3-(2-methylpropyl)-2-(thiophen-2-ylsulfanylmethyl)butanediamide sodium salt Batimastat sodium salt BB 94 sodiuM salt BB94 sodiuM salt BB-94 sodiuM salt BB-94 SODIUM SALT; BB 94 SODIUM SALT; BB94 SODIUM SALT 130464-84-5 C23H30N3NaO4S2