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4-Hydroxymethyl-1H-indazole

4-Hydroxymethyl-1H-indazole Structure
4-Hydroxymethyl-1H-indazole structure
CAS No.
709608-85-5
Chemical Name:
4-Hydroxymethyl-1H-indazole
Synonyms
(1H-Indazol-4-yl);1H-INDAZOLE-4-METHANOL;(1H-indazol-4-yl)methanol;4-Hydroxymethyl-1H-indazole
CBNumber:
CB12129287
Molecular Formula:
C8H8N2O
Molecular Weight:
148.16
MDL Number:
MFCD11052642
MOL File:
709608-85-5.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:14:43
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4-Hydroxymethyl-1H-indazole Properties

Boiling point 380.3±17.0 °C(Predicted)
Density 1.360±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
form solid
pka 13.92±0.40(Predicted)
color Grey to beige to brown
CAS DataBase Reference 709608-85-5

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338
HS Code  2933998090

4-Hydroxymethyl-1H-indazole price More Price(46)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 280075 4-(Hydroxymethyl)-1H-indazole Asreported 709608-85-5 50mg $340 2026-06-03 Buy
Usbiological 280075 4-(Hydroxymethyl)-1H-indazole Asreported 709608-85-5 100mg $466 2026-06-03 Buy
Usbiological 280075 4-(Hydroxymethyl)-1H-indazole Asreported 709608-85-5 250mg $566 2026-06-03 Buy
Usbiological 280075 4-(Hydroxymethyl)-1H-indazole Asreported 709608-85-5 500mg $871 2026-06-03 Buy
Usbiological 280075 4-(Hydroxymethyl)-1H-indazole Asreported 709608-85-5 1g $1184 2026-06-03 Buy
Product number Packaging Price Buy
280075 50mg $340 Buy
280075 100mg $466 Buy
280075 250mg $566 Buy
280075 500mg $871 Buy
280075 1g $1184 Buy

4-Hydroxymethyl-1H-indazole Chemical Properties, Uses, Production

Synthesis

Methyl 1H-indazole-4-carboxylate

192945-49-6

4-Hydroxymethyl-1H-indazole

709608-85-5

General procedure for the synthesis of 4-(hydroxymethyl)-1H-indazole from methyl indazole-4-carboxylate: synthesis of (1H-indazol-4-yl)-methanol (18b): the ester obtained above (40 mg, 0.23 mmol) was dissolved in 1 mL of tetrahydrofuran (THF) and the solution was cooled to 0°C. A THF solution (1.0 M, 2.3 mL, 2.3 mmol) of diisobutylaluminum hydride (DIBAL) was added slowly and dropwise. The addition of DIBAL was continued until the feedstock was completely consumed. Upon completion of the reaction, the reaction was quenched with saturated sodium potassium tartrate solution and gradually warmed to room temperature. The reaction mixture was extracted using ethyl acetate. The organic phases were combined and dried with anhydrous magnesium sulfate (MgSO4). Subsequently, the solvent was removed by reduced pressure distillation and the residue was purified by column chromatography (75% ethyl acetate/hexane). The final target product (20 mg, 60% yield) was obtained as a white solid. Mass spectrometry (electrospray ionization) analysis showed that the theoretical value of M + H = 149.1 and the measured value = 149.1.

References

[1] Patent: WO2007/51062, 2007, A2. Location in patent: Page/Page column 126-127

4-Hydroxymethyl-1H-indazole Preparation Products And Raw materials

Raw materials

Methyl 1H-indazole-4-carboxylate Diisobutylaluminium hydride Water Potassium sodium tartrate Tetrahydrofuran

Preparation Products

4-Hydroxymethyl-1H-indazole Suppliers

Global Suppliers ( 75)
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Energy Chemical 400-0056266 sales8178@energy-chemical.com China 44850 61
ZEROSCHEM.CO.,LTD. 10-61256048 13810278579; sales@zeroschem.com China 1401 59
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Sphinx Scientific Laboratory (Tianjin) Co., Ltd. 022-66211289-843 13672102692 contact@sphinxpharm.com China 361 62
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Nanjing Norris-Pharm Technology Co., Ltd 13901585132 sales@norris-pharm.com China 8869 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nantong MYBio-pharm. Co., Ltd. 0513-85921823 18662920231 sales@ntminyanmedical.com China 4565 58
Shanghai Balmxy Pharmaceutical Co., Ltd 021-24206007 13764915196 sales@balmxy.com China 6959 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
Energy Chemical 61
ZEROSCHEM.CO.,LTD. 59
Chemsky（shanghai）International Co.,Ltd. 50
Sphinx Scientific Laboratory (Tianjin) Co., Ltd. 62
T&W GROUP 58
Nanjing Norris-Pharm Technology Co., Ltd 55
Bide Pharmatech Ltd. 60
Nantong MYBio-pharm. Co., Ltd. 58
Shanghai Balmxy Pharmaceutical Co., Ltd 55

View Latest Price from 4-Hydroxymethyl-1H-indazole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Hydroxymethyl-1H-indazole pictures 2019-12-31 4-Hydroxymethyl-1H-indazole
709608-85-5
 $1.00 1KG 99% 1000KG Career Henan Chemical Co

4-Hydroxymethyl-1H-indazole Spectrum

4-Hydroxymethyl-1H-indazole(709608-85-5)1HNMR4-Hydroxymethyl-1H-indazole(709608-85-5)FT-IR

709608-85-5 (4-Hydroxymethyl-1H-indazole) Related Search:

1H-Indazole-4-carboxylic acid Methyl 3-formyl-4-indazolecarboxylate 6-Iodo-4-indazolecarboxylic acid methyl ester Ethyl 1H-indazole-4-carboxylate 3-Formyl-4-indazolecarboxylic acid
6-Bromo-4-methoxycarbonyl-1H-indazole-3-carboxylic acid 3-Iodo-4-(1H)indazole carboxylic acid methyl ester 6-Bromo-(1H)indazole-4-carboxylic acid 6-Bromo-4-indazolecarboxylic acid methyl ester 6-Nitro-4-indazolecarboxylic acid methyl ester
6-Amino-4-indazolecarboxylic acid methyl ester 1H-Indazole-3,4-dicarboxylic acid 4-methyl ester 3 Aldehyde, 4-methyl ester, 6-bromoindazole Methyl-3-bromoindazole-4-carboxylate 4-(1H)INDAZOLE CARBOXYLIC ACID METHYL ESTER
6-Bromo-3-hydroxy-4-indazolecarboxylic acid methyl ester 6-Bromo-3-cyano-4-indazolecarboxylic acid methyl ester 6-Chloro-4-indazolecarboxylic acid methyl ester

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4-Hydroxymethyl-1H-indazole 1H-INDAZOLE-4-METHANOL (1H-indazol-4-yl)methanol (1H-Indazol-4-yl) 709608-85-5 Building Blocks Indazole