ChemicalBook >> CAS DataBase List >>(S)-3-Chloro-1-phenyl-1-propanol

(S)-3-Chloro-1-phenyl-1-propanol

CAS No.
100306-34-1
Chemical Name:
(S)-3-Chloro-1-phenyl-1-propanol
Synonyms
Dapoxetine Impurity 37;3-CHLORO-1-PHENYL-1-PROPANOL;S(-)-3-CHLORO-1-PHENYLPROPANOL;a-(2-Chloroethyl)benzenemethanol;α-(2-Chloroethyl)benzenemethanol;(1S)-3-Chloro-1-phenylpropan-1-ol;2-(102-Chlorobenzoyl)benzoic&acid;ALPHA-(2-CHLOROETHYL)-BENZYL ALCOHOL;(S)-(-)-3-CHLORO-1-PHENYL-1-PROPANOL;(aS)-α-(2-Chloroethyl)benzenemethanol
CBNumber:
CB1222267
Molecular Formula:
C9H11ClO
Molecular Weight:
170.64
MDL Number:
MFCD00013309
MOL File:
100306-34-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:14:55
Product description Number Pack Size Price
(S)-(?)-3-Chloro-1-phenyl-1-propanol 98% 324612 1g $104
(S)-(?)-3-Chloro-1-phenyl-1-propanol 98% 324612 5g $150
(S)-(-)-3-Chloro-1-phenyl-1-propanol >98.0%(GC) C2424 1g $84
(S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) TRC-C379595-500MG 500mg $68
(S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) TRC-C379595-2G 2g $186
More product size

(S)-3-Chloro-1-phenyl-1-propanol Properties

Melting point 58-60 °C (lit.)
Boiling point 296 °C
Density 1.149
Flash point 132 °C
storage temp. Inert atmosphere,Room Temperature
solubility Chloroform (Sparingly), Methanol (Slightly)
form Solid
pka 13.92±0.20(Predicted)
color White to Off-White
optical activity [α]19/D 25°, c = 1 in chloroform
InChI InChI=1S/C9H11ClO/c10-7-6-9(11)8-4-2-1-3-5-8/h1-5,9,11H,6-7H2/t9-/m0/s1
InChIKey JZFUHAGLMZWKTF-VIFPVBQESA-N
SMILES C1C=C([C@@H](O)CCCl)C=CC=1
CAS DataBase Reference 100306-34-1(CAS DataBase Reference)
UNSPSC Code 12352101
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38-38-37-36
Safety Statements  26-37/39-39-37
WGK Germany  3
HS Code  29062990
NFPA 704
1
2 0

(S)-3-Chloro-1-phenyl-1-propanol price More Price(67)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 324612 (S)-(?)-3-Chloro-1-phenyl-1-propanol 98% 100306-34-1 1g $104 2023-01-07 Buy
Sigma-Aldrich 324612 (S)-(?)-3-Chloro-1-phenyl-1-propanol 98% 100306-34-1 5g $150 2023-01-07 Buy
TCI Chemical C2424 (S)-(-)-3-Chloro-1-phenyl-1-propanol >98.0%(GC) 100306-34-1 1g $84 2026-04-30 Buy
TRC TRC-C379595-500MG (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) 100306-34-1 500mg $68 2026-06-03 Buy
TRC TRC-C379595-2G (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) 100306-34-1 2g $186 2026-06-03 Buy
Product number Packaging Price Buy
324612 1g $104 Buy
324612 5g $150 Buy
C2424 1g $84 Buy
TRC-C379595-500MG 500mg $68 Buy
TRC-C379595-2G 2g $186 Buy

(S)-3-Chloro-1-phenyl-1-propanol Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powde

Uses

(S)-(-)-3-Chloro-1-phenyl-1-propanol (cas# 100306-34-1) is a compound useful in organic synthesis.

Synthesis

3-Chloropropiophenone

936-59-4

(S)-3-Chloro-1-phenyl-1-propanol

100306-34-1

The general procedure for the synthesis of (S)-(-)-3-chloro-1-phenyl-1-propanol from 3-chloropropiophenone was as follows: 3.36 g (40.0 mmol) of potassium formate (HCOOK) was used as a hydrogen source under argon protection, 2.609 mg (4.0 μmol) of Cp*IrCl[(S,S)-MsDPEN] was used as a catalyst, and 1.349 g (8.0 mmol) β-chloropropiophenone in a 20 mL Schlenk tube. 2 mL of water and 2 mL of toluene were added to the reaction system and the resulting mixture was stirred at 50 °C for 24 hours. Upon completion of the reaction, the organic phase was washed three times with 3 mL of water, followed by distillation under reduced pressure to remove toluene to give optically active (S)-(-)-3-chloro-1-phenyl-1-propanol. The optical purity of the product was confirmed by GC analysis to be 85% ee in 94% yield.

References

[1] Patent: US2009/62573, 2009, A1. Location in patent: Page/Page column 7; 14
[2] Organic and Biomolecular Chemistry, 2014, vol. 12, # 6, p. 1009 - 1017
[3] Patent: KR2015/116956, 2015, A. Location in patent: Paragraph 0176-0179
[4] Patent: KR2016/44117, 2016, A. Location in patent: Paragraph 0063-0066
[5] Organic and Biomolecular Chemistry, 2011, vol. 9, # 10, p. 3854 - 3862

(S)-3-Chloro-1-phenyl-1-propanol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 243)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Chuanghai Biotechnology Co., Ltd
+86-15350571055 Sibel@chuanghaibio.com China 8737 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29626 60
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29766 58
Zhejiang ZETian Fine Chemicals Co. LTD
18957127338 stella@zetchem.com China 2993 58
Jinan Carbotang Biotech Co.,Ltd.
+8615866703830 figo.gao@foxmail.com China 8491 58
HaBo Hong Kong Co., Limited.
+86-25-18512596065 info@habotech.com CHINA 931 58
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14320 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63645 58
CONIER CHEM AND PHARMA LIMITED
sales@conier.com China 49906 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9631 58

View Lastest Price from (S)-3-Chloro-1-phenyl-1-propanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-3-Chloro-1-phenyl-1-propanol pictures 2026-03-20 (S)-3-Chloro-1-phenyl-1-propanol
100306-34-1
1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd
Dapoxetine Impurity 77 pictures 2026-03-12 Dapoxetine Impurity 77
100306-34-1
10mg 0.98 5g ShenZhen H&D Pharmaceutical Technology Co., LTD
(S)-3-Chloro-1-phenyl-1-propanol pictures 2021-08-12 (S)-3-Chloro-1-phenyl-1-propanol
100306-34-1
$10.00-15.00 1KG 99%+ HPLC Zhuozhou Wenxi import and Export Co., Ltd
(S)-(-)-3-CHLORO-1-PHENYL-1-PROPANOL ALPHA-(2-CHLOROETHYL)-BENZYL ALCOHOL 3-CHLORO-1-PHENYL-1-PROPANOL (S)-(-)-3-CHLORO-1-PHENYL-1-PROPANOL, 98 % (99% EE/GLC) S(-)-3-CHLORO-1-PHENYLPROPANOL (S)-()-α-(2-Chloroethyl)benzyl alcohol (aS)-a-(2-Chloroethyl)benzenemethanol a-(2-Chloroethyl)benzenemethanol (aS)-α-(2-Chloroethyl)benzenemethanol α-(2-Chloroethyl)benzenemethanol α-(2-Chloroethyl)benzyl alcohol, (S)-(-)-α-(2-Chloroethyl)benzyl alcohol, (S)-(-)-3-Chloro-1-phenylpropanol (S)-(-)-3-Chloro-1-phenyl-1-propanol, 98+% (αS)-α-(2-Chloroethyl)benzeneMethanol (S)-(-)-alpha-(2-Chloroethyl)benzyl Alcohol (1S)-3-Chloro-1-phenylpropan-1-ol BenzeneMethanol, α-(2-chloroethyl)-, (αS)- Benzenemethanol, |á-(2-chloroethyl)-, (|áS)- (S)-(-)-3-Chloro-1-phenyl-1-propanol, 98+% white to yellow solid Dapoxetine Impurity 37 (1S)-3-Chloro-1-phenylpropan-1-ol 95+% (S)-(-)-3-Chloro-1-phenyl-1-propanol > 2-(102-Chlorobenzoyl)benzoic&acid (S)-(?)-3-Chloro-1-phenyl-1-propanol (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) 100306-34-1 C9H11ClO Alcohols Organic Building Blocks Chiral Building Blocks Asymmetric Synthesis Aromatics Compounds Aromatics Chiral Reagents Heterocyclic Compounds chiral