(S)-3-Chloro-1-phenyl-1-propanol
- CAS No.
- 100306-34-1
- Chemical Name:
- (S)-3-Chloro-1-phenyl-1-propanol
- Synonyms
- Dapoxetine Impurity 37;3-CHLORO-1-PHENYL-1-PROPANOL;S(-)-3-CHLORO-1-PHENYLPROPANOL;a-(2-Chloroethyl)benzenemethanol;α-(2-Chloroethyl)benzenemethanol;(1S)-3-Chloro-1-phenylpropan-1-ol;2-(102-Chlorobenzoyl)benzoic&acid;ALPHA-(2-CHLOROETHYL)-BENZYL ALCOHOL;(S)-(-)-3-CHLORO-1-PHENYL-1-PROPANOL;(aS)-α-(2-Chloroethyl)benzenemethanol
- CBNumber:
- CB1222267
- Molecular Formula:
- C9H11ClO
- Molecular Weight:
- 170.64
- MDL Number:
- MFCD00013309
- MOL File:
- 100306-34-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| (S)-(?)-3-Chloro-1-phenyl-1-propanol 98% | 324612 | 1g | $104 |
| (S)-(?)-3-Chloro-1-phenyl-1-propanol 98% | 324612 | 5g | $150 |
| (S)-(-)-3-Chloro-1-phenyl-1-propanol >98.0%(GC) | C2424 | 1g | $84 |
| (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) | TRC-C379595-500MG | 500mg | $68 |
| (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) | TRC-C379595-2G | 2g | $186 |
| More product size | |||
| Melting point | 58-60 °C (lit.) |
|---|---|
| Boiling point | 296 °C |
| Density | 1.149 |
| Flash point | 132 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Chloroform (Sparingly), Methanol (Slightly) |
| form | Solid |
| pka | 13.92±0.20(Predicted) |
| color | White to Off-White |
| optical activity | [α]19/D 25°, c = 1 in chloroform |
| InChI | InChI=1S/C9H11ClO/c10-7-6-9(11)8-4-2-1-3-5-8/h1-5,9,11H,6-7H2/t9-/m0/s1 |
| InChIKey | JZFUHAGLMZWKTF-VIFPVBQESA-N |
| SMILES | C1C=C([C@@H](O)CCCl)C=CC=1 |
| CAS DataBase Reference | 100306-34-1(CAS DataBase Reference) |
| UNSPSC Code | 12352101 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) | ![]() GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38-38-37-36 | |||||||||
| Safety Statements | 26-37/39-39-37 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29062990 | |||||||||
| NFPA 704 |
|
(S)-3-Chloro-1-phenyl-1-propanol price More Price(67)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 324612 | (S)-(?)-3-Chloro-1-phenyl-1-propanol 98% | 100306-34-1 | 1g | $104 | 2023-01-07 | Buy |
| Sigma-Aldrich | 324612 | (S)-(?)-3-Chloro-1-phenyl-1-propanol 98% | 100306-34-1 | 5g | $150 | 2023-01-07 | Buy |
| TCI Chemical | C2424 | (S)-(-)-3-Chloro-1-phenyl-1-propanol >98.0%(GC) | 100306-34-1 | 1g | $84 | 2026-04-30 | Buy |
| TRC | TRC-C379595-500MG | (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) | 100306-34-1 | 500mg | $68 | 2026-06-03 | Buy |
| TRC | TRC-C379595-2G | (S)-(-)-3-Chloro-1-phenyl-1-propanol (>90%) | 100306-34-1 | 2g | $186 | 2026-06-03 | Buy |
(S)-3-Chloro-1-phenyl-1-propanol Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powde
Uses
(S)-(-)-3-Chloro-1-phenyl-1-propanol (cas# 100306-34-1) is a compound useful in organic synthesis.
Synthesis
936-59-4
100306-34-1
The general procedure for the synthesis of (S)-(-)-3-chloro-1-phenyl-1-propanol from 3-chloropropiophenone was as follows: 3.36 g (40.0 mmol) of potassium formate (HCOOK) was used as a hydrogen source under argon protection, 2.609 mg (4.0 μmol) of Cp*IrCl[(S,S)-MsDPEN] was used as a catalyst, and 1.349 g (8.0 mmol) β-chloropropiophenone in a 20 mL Schlenk tube. 2 mL of water and 2 mL of toluene were added to the reaction system and the resulting mixture was stirred at 50 °C for 24 hours. Upon completion of the reaction, the organic phase was washed three times with 3 mL of water, followed by distillation under reduced pressure to remove toluene to give optically active (S)-(-)-3-chloro-1-phenyl-1-propanol. The optical purity of the product was confirmed by GC analysis to be 85% ee in 94% yield.
References
[1] Patent: US2009/62573, 2009, A1. Location in patent: Page/Page column 7; 14
[2] Organic and Biomolecular Chemistry, 2014, vol. 12, # 6, p. 1009 - 1017
[3] Patent: KR2015/116956, 2015, A. Location in patent: Paragraph 0176-0179
[4] Patent: KR2016/44117, 2016, A. Location in patent: Paragraph 0063-0066
[5] Organic and Biomolecular Chemistry, 2011, vol. 9, # 10, p. 3854 - 3862
(S)-3-Chloro-1-phenyl-1-propanol Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Chuanghai Biotechnology Co., Ltd | +86-15350571055 | Sibel@chuanghaibio.com | China | 8737 | 58 |
| Capot Chemical Co.,Ltd. | +86-(0)57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2993 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8491 | 58 |
| HaBo Hong Kong Co., Limited. | +86-25-18512596065 | info@habotech.com | CHINA | 931 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14320 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9631 | 58 |
View Lastest Price from (S)-3-Chloro-1-phenyl-1-propanol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
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2026-03-20 | (S)-3-Chloro-1-phenyl-1-propanol
100306-34-1
|
1KG | 99% | 20 mt | Hebei Chuanghai Biotechnology Co., Ltd | ||
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2026-03-12 | Dapoxetine Impurity 77
100306-34-1
|
10mg | 0.98 | 5g | ShenZhen H&D Pharmaceutical Technology Co., LTD | ||
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2021-08-12 | (S)-3-Chloro-1-phenyl-1-propanol
100306-34-1
|
$10.00-15.00 | 1KG | 99%+ HPLC | Zhuozhou Wenxi import and Export Co., Ltd |
-

- (S)-3-Chloro-1-phenyl-1-propanol
100306-34-1
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
-

- Dapoxetine Impurity 77
100306-34-1
- 0.98
- ShenZhen H&D Pharmaceutical Technology Co., LTD
-

- (S)-3-Chloro-1-phenyl-1-propanol
100306-34-1
- $10.00-15.00
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd





