TIPLIMOTIDE
- CAS No.
- 178823-49-9
- Chemical Name:
- TIPLIMOTIDE
- Synonyms
- TIPLIMOTIDE;L-Proline, D-alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl-
- CBNumber:
- CB12451287
- Molecular Formula:
- C87H142N24O21
- Molecular Weight:
- 1860.21
- MDL Number:
- MFCD09837784
- MOL File:
- 178823-49-9.mol
- TDS File:
- TDS
| Density | 1.42±0.1 g/cm3(Predicted) |
|---|---|
| pka | 3.39±0.20(Predicted) |
| FDA UNII | 6VN101530Y |
TIPLIMOTIDE price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| aablocks | AA0026BG | L-Proline, D-alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl- ≥95% | 178823-49-9 | 1mg | $184 | 2026-05-28 | Buy |
| aablocks | AA0026BG | L-Proline, D-alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl- ≥95% | 178823-49-9 | 5mg | $436 | 2026-05-28 | Buy |
| aablocks | AA0026BG | L-Proline, D-alanyl-L-lysyl-L-prolyl-L-valyl-L-valyl-L-histidyl-L-leucyl-L-phenylalanyl-L-alanyl-L-asparaginyl-L-isoleucyl-L-valyl-L-threonyl-L-prolyl-L-arginyl-L-threonyl- ≥95% | 178823-49-9 | 10mg | $602 | 2026-05-28 | Buy |
| American Custom Chemicals Corporation | API0019434 | TIPLIMOTIDE 95.00% | 178823-49-9 | 5MG | $497.74 | 2021-12-16 | Buy |
TIPLIMOTIDE Chemical Properties, Uses, Production
Uses
Tiplimotide (NBI-5788) is an altered peptide ligand (APL) designed from an immunodominant region (83-99) of the neuroantigen myelin basic protein (MBP). Tiplimotide can selectively reduce the production of inflammatory cytokines by pathogenic T-cells. Tiplimotide can be used for the research of multiple sclerosis (MS)[1][2].
References
[1] P D Crowe, et al. NBI-5788, an altered MBP83-99 peptide, induces a T-helper 2-like immune response in multiple sclerosis patients. Ann Neurol. 2000 Nov;48(5):758-65. PMID:11079539
[2] Maria Katsara, et al. A double mutation of MBP(83-99) peptide induces IL-4 responses and antagonizes IFN-gamma responses. J Neuroimmunol. 2008 Aug 30;200(1-2):77-89. DOI:10.1016/j.jneuroim.2008.06.013
TIPLIMOTIDE Preparation Products And Raw materials
Raw materials
Preparation Products
TIPLIMOTIDE Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12323 | 58 |
| Hangzhou Peptidego Biotech Co.,Ltd. | 0571-87213919 15967184799 | Eric@peptidego.com | China | 7872 | 58 |
| Hangzhou Sinoda Pharmaceutical Technology Co. LTD | 0571-87213919 17306812703 | 3007955328@qq.com | China | 7446 | 58 |
| Shanghai HongTide Biotechnology Co.,Ltd. | 15318089928 | alex@hanhonggroup.com | China | 4604 | 58 |
| Nanjing Typeptide Biotechnology Co.,Ltd. | 19961912513; 19941518170 | sales@typeptide.com | China | 4449 | 58 |
| YantaiBio | 13758194781; 13758194781 | 764619768@qq.com | China | 1773 | 58 |
| Fuan Bio | 15002819872 | 2845971812@qq.com | China | 2103 | 58 |
| ANHUI BYERSEN BIOTECH CO. LTD | +8617355064950 | amy@byersenchemical.com | China | 10000 | 58 |
