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1-cyclopropylnaphthalene

1-cyclopropylnaphthalene Structure
1-cyclopropylnaphthalene structure
CAS No.
25033-19-6
Chemical Name:
1-cyclopropylnaphthalene
Synonyms
1-Naphthylcyclopropane;1-cyclopropylnapthalene;1-cyclopropylnaphthalene;Thiophene,2-(5-bromoethyl)-;Naphthalene, 1-cyclopropyl-
CBNumber:
CB12499836
Molecular Formula:
C13H12
Molecular Weight:
168.23
MDL Number:
MFCD00760297
MOL File:
25033-19-6.mol
MSDS File:
SDS
Last updated:2026-05-27 23:15:52
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1-cyclopropylnaphthalene Properties

Boiling point 152-154 °C(Press: 18 Torr)
Density 1.110
storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  Environment (GHS09)
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P391-P501
REACH Registrations Inactive

1-cyclopropylnaphthalene price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Activate Scientific AS90234 1-Cyclopropylnaphthalene 97% 25033-19-6 1g $56 2026-06-04 Buy
Activate Scientific AS90234 1-Cyclopropylnaphthalene 97% 25033-19-6 5g $160 2026-06-04 Buy
Activate Scientific AS90234 1-Cyclopropylnaphthalene 97% 25033-19-6 25g $463 2026-06-04 Buy
Matrix Scientific 223975 1-Cyclopropylnaphthalene 25033-19-6 5.00g $286 2026-05-18 Buy
Matrix Scientific 223975 1-Cyclopropylnaphthalene 25033-19-6 10.00g $1000 2026-05-18 Buy
Product number Packaging Price Buy
AS90234 1g $56 Buy
AS90234 5g $160 Buy
AS90234 25g $463 Buy
223975 5.00g $286 Buy
223975 10.00g $1000 Buy

1-cyclopropylnaphthalene Chemical Properties, Uses, Production

Uses

1-Cyclopropylnaphthalene can be a starting material in the synthesis of 3-hydroxy-3-naphthyl-propyl nitrate. 1-Cyclopropylnaphthalene is a derivative of Naphthalene (N345600). Naphthalene is an abundant polycyclic aromatic hydrocarbon that is persistent, bioaccumulative, toxic and found in tobacco smoke and urban air.

Synthesis

1-Bromonaphthalene

90-11-9

Cyclopropylmagnesium bromide

23719-80-4

1-cyclopropylnaphthalene

25033-19-6

General procedure for the synthesis of 1-cyclopropylnaphthalene from 1-bromonaphthalene and cyclopropylmagnesium bromide: Cyclopropylmagnesium bromide (150 mL, 0.5 M in tetrahydrofuran) was added slowly and dropwise to a solution of tetrahydrofuran (10 mL) containing 1-bromonaphthalene (10 g, 50 mmol) and [1,3-bis(diphenylphosphino)propane]nickel(II) dichloride at 0 °C. The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was extracted by adding ethyl acetate and aqueous ammonium chloride solution to the residue. The organic layer was separated, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Finally, the residue was purified by silica gel column chromatography to afford 1-cyclopropylnaphthalene (6.4 g, 76% yield).

References

[1] Patent: WO2009/70740, 2009, A2. Location in patent: Page/Page column 89
[2] Patent: WO2006/26356, 2006, A2. Location in patent: Page/Page column 20
[3] Patent: WO2011/85009, 2011, A2. Location in patent: Page/Page column 36
[4] Patent: WO2014/8295, 2014, A1. Location in patent: Paragraph 0345-0348

1-cyclopropylnaphthalene Preparation Products And Raw materials

Raw materials

3-(Dimethylamino)-1-(naphthalen-1-yl)propan-1-one hydrochloride 1-Bromonaphthalene Cyclopropylmagnesium bromide Cyclopropylboronic acid Ammonium chloride

Preparation Products

4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione RDEA-594 sodiuM Naphthalene, 1-cyclopropyl-4-isothiocyanato-

1-cyclopropylnaphthalene Suppliers

Global Suppliers ( 162)
Supplier Tel Email Country ProdList Advantage
Jia Xing Isenchem Co.,Ltd 0573-85285100 18627885956 isenchem@163.com China 9389 66
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16305 64
Jiangsu Vcare PharmaTech Co., Ltd. 025-58741518 13327700685 sales@vcarepharmatech.com China 281 61
Shanghai Sphchem Co., Ltd. 021-56491756 13512199871 2819742715@qq.com China 3994 55
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
AstaTech (Chengdu) Pharma. Co., Ltd. 15928766785 15928766785 wupengcheng@astatech.cn China 1997 55
Chem-Stone Co.,Ltd. 020-82185713,82185709 13418171485 sales@chem-stone.com China 743 56
Supplier Advantage
Jia Xing Isenchem Co.,Ltd 66
Adamas Reagent, Ltd. 59
Nanjing Chemlin Chemical Co., Ltd 64
Jiangsu Vcare PharmaTech Co., Ltd. 61
Shanghai Sphchem Co., Ltd. 55
BOC Sciences 65
T&W GROUP 58
Shanghai Topbiochem Technology Co., Ltd 58
AstaTech (Chengdu) Pharma. Co., Ltd. 55
Chem-Stone Co.,Ltd. 56

View Latest Price from 1-cyclopropylnaphthalene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-cyclopropylnaphthalene pictures 2026-03-20 1-cyclopropylnaphthalene
25033-19-6
 $10.00 1KG 99% 10 mt Hebei Chuanghai Biotechnology Co., Ltd
1-cyclopropylnaphthalene pictures 2025-06-27 1-cyclopropylnaphthalene
25033-19-6
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
1-cyclopropylnaphthalene pictures 2023-05-04 1-cyclopropylnaphthalene
25033-19-6
 $40.00-48.00 1公斤 99.% 200 tons Guangzhou Sunton Biotechnology Co., Ltd.

25033-19-6 (1-cyclopropylnaphthalene) Related Search:

1-cyclopropyl-7-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid Lesinurad Impurity 4 Lesinurad Impurity 10 Lesinurad Impurity J 4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione
Naphthalene, 1-cyclopropyl-4-isothiocyanato- Lesinurad Impurity 23 Lesinurad Impurity 5 Sodium Salt 3-bromo-4-(4-cyclopropylnaphthalen-1-yl)-1H-1,2,4-triazole-5(4H)-thione N-(4-Cyclopropyl-1-naphthalenyl)-2-formylhydrazinecarbothioamide
lesinurad int RDEA 594 Lesinurad Impurity 38 Lesinurad Impurity 32 (Mixture of Isomers) Lesinurad Impurity H
Lesinurad Impurity 24 Lesinurad Impurity N Lesinurad Impurity 27

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1-cyclopropylnaphthalene 1-cyclopropylnapthalene 1-Naphthylcyclopropane Naphthalene, 1-cyclopropyl- Thiophene,2-(5-bromoethyl)- 25033-19-6 Naphthalene series strong recommend Lesinurad (RDEA-594)