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1-cyclopropylnaphthalene

CAS No.
25033-19-6
Chemical Name:
1-cyclopropylnaphthalene
Synonyms
1-Naphthylcyclopropane;1-cyclopropylnapthalene;1-cyclopropylnaphthalene;Thiophene,2-(5-bromoethyl)-;Naphthalene, 1-cyclopropyl-
CBNumber:
CB12499836
Molecular Formula:
C13H12
Molecular Weight:
168.23
MDL Number:
MFCD00760297
MOL File:
25033-19-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:45

1-cyclopropylnaphthalene Properties

Boiling point 152-154 °C(Press: 18 Torr)
Density 1.110
storage temp. Sealed in dry,Room Temperature

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Warning
Hazard statements  H410
Precautionary statements  P273-P391-P501

1-cyclopropylnaphthalene price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C987380 1-Cyclopropylnaphthalene 25033-19-6 250mg $165 2021-12-16 Buy
AK Scientific 6248BB 1-Cyclopropylnaphthalene 25033-19-6 25g $463 2021-12-16 Buy
American Custom Chemicals Corporation CHM1011432 1-CYCLOPROPYLNAPHTHALENE 95.00% 25033-19-6 5MG $500.43 2021-12-16 Buy
Ambeed A150264 1-Cyclopropylnaphthalene 97% 25033-19-6 100g $885 2021-12-16 Buy
Alichem 25033196 1-Cyclopropylnaphthalene 25033-19-6 25g $488.79 2021-12-16 Buy
Product number Packaging Price Buy
C987380 250mg $165 Buy
6248BB 25g $463 Buy
CHM1011432 5MG $500.43 Buy
A150264 100g $885 Buy
25033196 25g $488.79 Buy

1-cyclopropylnaphthalene Chemical Properties,Uses,Production

Uses

1-Cyclopropylnaphthalene can be a starting material in the synthesis of 3-hydroxy-3-naphthyl-propyl nitrate. 1-Cyclopropylnaphthalene is a derivative of Naphthalene (N345600). Naphthalene is an abundant polycyclic aromatic hydrocarbon that is persistent, bioaccumulative, toxic and found in tobacco smoke and urban air.

Synthesis

1-Bromonaphthalene

90-11-9

Cyclopropylmagnesium bromide

23719-80-4

1-cyclopropylnaphthalene

25033-19-6

General procedure for the synthesis of 1-cyclopropylnaphthalene from 1-bromonaphthalene and cyclopropylmagnesium bromide: Cyclopropylmagnesium bromide (150 mL, 0.5 M in tetrahydrofuran) was added slowly and dropwise to a solution of tetrahydrofuran (10 mL) containing 1-bromonaphthalene (10 g, 50 mmol) and [1,3-bis(diphenylphosphino)propane]nickel(II) dichloride at 0 °C. The reaction mixture was stirred at room temperature for 16 hours. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. The residue was extracted by adding ethyl acetate and aqueous ammonium chloride solution to the residue. The organic layer was separated, dried with anhydrous sodium sulfate, filtered and concentrated under reduced pressure. Finally, the residue was purified by silica gel column chromatography to afford 1-cyclopropylnaphthalene (6.4 g, 76% yield).

References

[1] Patent: WO2009/70740, 2009, A2. Location in patent: Page/Page column 89
[2] Patent: WO2006/26356, 2006, A2. Location in patent: Page/Page column 20
[3] Patent: WO2011/85009, 2011, A2. Location in patent: Page/Page column 36
[4] Patent: WO2014/8295, 2014, A1. Location in patent: Paragraph 0345-0348

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View Lastest Price from 1-cyclopropylnaphthalene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Cyclopropylnaphthalene pictures 2025-08-14 1-Cyclopropylnaphthalene
25033-19-6
US $100.00 / kg 1kg 99% 1000tons Hebei Mujin Biotechnology Co.,Ltd
1-cyclopropylnaphthalene pictures 2025-08-14 1-cyclopropylnaphthalene
25033-19-6
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mujin Biotechnology Co.,Ltd
1-cyclopropylnaphthalene pictures 2025-06-27 1-cyclopropylnaphthalene
25033-19-6
US $0.00-0.00 / KG 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
1-cyclopropylnaphthalene 1-cyclopropylnapthalene 1-Naphthylcyclopropane Naphthalene, 1-cyclopropyl- Thiophene,2-(5-bromoethyl)- 25033-19-6 Naphthalene series strong recommend Lesinurad (RDEA-594)