ChemicalBook >> CAS DataBase List >>2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide structure

CAS No.: 474960-44-6

Chemical Name:: 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide

Synonyms: CS-1139;SB 657510;SB 657510,SB657510;SB-657510, 10 mM in DMSO;(R)-2-Bromo-N-(4-chloro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)-4,5-dimethoxybenzenesulfonamide;2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide;2-bromo-N-[4-chloro-3-[(3R)-1-methylpyrrolidin-3-yl]oxy-phenyl]-4,5-dimethoxy-benzenesulfonamide;BenzenesulfonaMide, 2-broMo-N-[4-chloro-3-[[(3R)-1-Methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-diMethoxy-

CBNumber:: CB12518915

Molecular Formula:: C19H22BrClN2O5S

Molecular Weight:: 505.81

MDL Number:: MFCD16618389

MOL File:: 474960-44-6.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-05-27 23:16:04

Product description	Number	Pack Size	Price
SB 657510 ≥98% (HPLC)	S7326	5mg	$171
SB 657510 ≥98% (HPLC)	S7326	25mg	$678
SB-657510 ≥95%	42321	5mg	$160
SB-657510 ≥95%	42321	10mg	$304
SB-657510 ≥95%	42321	50mg	$798

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2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Properties

Boiling point	585.0±60.0 °C(Predicted)
Density	1.512±0.06 g/cm3(Predicted)
storage temp.	Store at RT
solubility	DMSO: ≥30mg/mL
pka	6.60±0.10(Predicted)
form	powder
color	white to off-white
InChI	1S/C19H22BrClN2O5S/c1-23-7-6-13(11-23)28-16-8-12(4-5-15(16)21)22-29(24,25)19-10-18(27-3)17(26-2)9-14(19)20/h4-5,8-10,13,22H,6-7,11H2,1-3H3/t13-/m1/s1
InChIKey	KQCZCINJGIRLCD-CYBMUJFWSA-N
SMILES	COc1cc(Br)c(cc1OC)S(=O)(=O)Nc2ccc(Cl)c(O[C@@H]3CCN(C)C3)c2
UNSPSC Code	12352200
NACRES	NA.77

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H315-H319-H335
Precautionary statements	P261-P305+P351+P338
target organs	Respiratory system
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
WGK Germany	3
Storage Class	11 - Combustible Solids
Hazard Classifications	Eye Irrit. 2 Skin Irrit. 2 STOT SE 3

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide price More Price(39)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S7326	SB 657510 ≥98% (HPLC)	474960-44-6	5mg	$171	2026-04-30	Buy
Sigma-Aldrich	S7326	SB 657510 ≥98% (HPLC)	474960-44-6	25mg	$678	2026-04-30	Buy
Cayman Chemical	42321	SB-657510 ≥95%	474960-44-6	5mg	$160	2026-04-30	Buy
Cayman Chemical	42321	SB-657510 ≥95%	474960-44-6	10mg	$304	2026-04-30	Buy
Cayman Chemical	42321	SB-657510 ≥95%	474960-44-6	50mg	$798	2026-04-30	Buy

Product number	Packaging	Price	Buy
S7326	5mg	$171	Buy
S7326	25mg	$678	Buy
42321	5mg	$160	Buy
42321	10mg	$304	Buy
42321	50mg	$798	Buy

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Chemical Properties,Uses,Production

Uses

SB 657510 is a selective GPR14 (urotensin-II (UT) receptor) antagonist.

Biological Activity

SB 657510 slows development of diabetes-associated atherosclerosis in mouse model of diabetes.1 ', 'SB-657510 is a selective urotensin-II (UT) receptor antagonist. Human urotensin-II (hU-II) is proposed to play a significant role in cardiorenal and metabolic disease states, including heart failure, atherosclerosis, hypertension.

in vivo

SB-657510 inhibits the progression of high-fat diet induced atherosclerosis and diabetes-associated atherosclerosis^[1].
Levels of phosphorylated ERK are significantly attenuated in the aorta of SB-657510-treated (30 mg/kg/day) diabetic mice (Male Apoe KO mice)^[3].

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Preparation Products And Raw materials

Raw materials

Preparation Products

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Suppliers

Global( 51)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354; +1-00000000000	marketing@targetmol.com	United States	32431	58
Career Henan Chemica Co	+86-0371-86658258 +86-13203830695	laboratory@coreychem.com	China	30203	58
TargetMol Chemicals Inc.	+1-781-999-5354;	support@targetmol.com	United States	38999	58
Aladdin Scientific		tp@aladdinsci.com	United States	54746	58
Amadis Chemical Company Limited	571-89925085	sales@amadischem.com	China	131885	58
Nanjing Chemlin Chemical Co., Ltd	025-83697070 13770331960	info@chemlin.com.cn	China	16305	64
Shanghai YuanYe Biotechnology Co., Ltd.	15026964105	2881489226@qq.com	China	89667	60
Shanghai Chaolan Chemical Technology Center	QQ：65489617 13301690235	Sales@ATKchemical.com	China	9695	58
BOC Sciences	--	info@bocsci.com	USA	0	65
Shanghai Dongyang Biotechnology Co., Ltd.	0512-13601744364 13601744364	chemsharker@126.com	China	1158	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Career Henan Chemica Co	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Amadis Chemical Company Limited	58
Nanjing Chemlin Chemical Co., Ltd	64
Shanghai YuanYe Biotechnology Co., Ltd.	60
Shanghai Chaolan Chemical Technology Center	58
BOC Sciences	65
Shanghai Dongyang Biotechnology Co., Ltd.	58

View Lastest Price from 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2026-05-11	SB-657510 474960-44-6	$45.00-197.00		98.06%	10g	TargetMol Chemicals Inc.
	2026-04-22	SB-657510 474960-44-6	$45.00-197.00		98.06%	10g	TargetMol Chemicals Inc.

SB-657510
474960-44-6
$45.00-197.00
98.06%
TargetMol Chemicals Inc.

SB-657510
474960-44-6
$45.00-197.00
98.06%
TargetMol Chemicals Inc.

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide Spectrum

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide(474960-44-6)¹HNMR

474960-44-6(2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide)Related Search:

N-[2-(Dimethylamino)ethyl]-N-[[4′-[[(2-phenylethyl)amino]methyl][1,1′-biphenyl]-4-yl]methyl]-cyclopentanepropanamide dihydrochloride 6-[2-tert-Butyl-5-(6-methyl-pyridin-2-yl)-1H-imidazol-4-yl]-quinoxaline 2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride 2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide 9,12-Octadecadienoic acid, 12-nitro-, (9Z,12E)-

norastemizole

1of2

2-Bromo-N-[4-chloro-3-[[(3R)-1-methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-dimethoxybenzenesulfonamide CS-1139 SB 657510 BenzenesulfonaMide, 2-broMo-N-[4-chloro-3-[[(3R)-1-Methyl-3-pyrrolidinyl]oxy]phenyl]-4,5-diMethoxy- 2-bromo-N-[4-chloro-3-[(3R)-1-methylpyrrolidin-3-yl]oxy-phenyl]-4,5-dimethoxy-benzenesulfonamide SB 657510,SB657510 (R)-2-Bromo-N-(4-chloro-3-((1-methylpyrrolidin-3-yl)oxy)phenyl)-4,5-dimethoxybenzenesulfonamide SB-657510, 10 mM in DMSO 474960-44-6 C19H22BrClN2O5S C19H22BrCIN2O5S