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ChemicalBook >> CAS DataBase List >>5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Structure
5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester structure
CAS No.
474330-54-6
Chemical Name:
5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester
Synonyms
Methyl 5-aMino-2-broMo-4-Methylbenzoate;5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester;methyl 5-amino-2-bromo-4-methylbenzoate hydrochloride;Benzoic acid, 5-aMino-2-broMo-4-Methyl-, Methyl ester
CBNumber:
CB12609963
Molecular Formula:
C9H10BrNO2
Molecular Weight:
244.09
MDL Number:
MOL File:
474330-54-6.mol
MSDS File:
SDS
Last updated:2026-05-27 23:28:21
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5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Properties

Boiling point 328.4±37.0 °C(Predicted)
Density 1.506±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2–8 °C
pka 2.60±0.10(Predicted)
Appearance Light brown to gray Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P280-P305+P351+P338

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester price More Price(29)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth ZTA33054 methyl 5-amino-2-bromo-4-methylbenzoate 474330-54-6 5g $295 2026-06-05 Buy
Synthonix M49799 Methyl 5-amino-2-bromo-4-methylbenzoate 97% 474330-54-6 250mg $29 2026-05-06 Buy
Synthonix M49799 Methyl 5-amino-2-bromo-4-methylbenzoate 97% 474330-54-6 1g $35 2026-05-06 Buy
Synthonix M49799 Methyl 5-amino-2-bromo-4-methylbenzoate 97% 474330-54-6 5g $160 2026-05-06 Buy
Synthonix M49799 Methyl 5-amino-2-bromo-4-methylbenzoate 97% 474330-54-6 10g $310 2026-05-06 Buy
Product number Packaging Price Buy
ZTA33054 5g $295 Buy
M49799 250mg $29 Buy
M49799 1g $35 Buy
M49799 5g $160 Buy
M49799 10g $310 Buy

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Chemical Properties, Uses, Production

Synthesis

Methanol

67-56-1

5-amino-2-bromo-4-methylbenzoic acid

745048-63-9

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester

474330-54-6

General procedure for the synthesis of methyl 5-amino-2-bromo-4-methylbenzoate from methanol and 5-amino-2-bromo-4-methylbenzoic acid: 5-amino-2-bromo-4-methylbenzoic acid (39.90 g, 0.17 mol) was suspended in methanol (500 mL). The suspension was cooled to 0 to 5 °C and thionyl chloride (40 mL, 0.54 mol) was added slowly and dropwise. The reaction mixture was heated to reflux for 6 hours. Upon completion of the reaction, the solution was concentrated under reduced pressure and the residue was diluted with ice water (500 g). The pH was adjusted to 7.5 with saturated aqueous sodium bicarbonate and subsequently extracted with ethyl acetate (3 x 200 mL). The organic phases were combined, washed with saturated saline (3 x 200 mL), dried over anhydrous magnesium sulfate, filtered and concentrated to dryness under reduced pressure to afford methyl 5-amino-2-bromo-4-methylbenzoate as a white solid (40.35 g, 95% yield).

References

[1] Patent: US2007/275907, 2007, A1. Location in patent: Page/Page column 19
[2] Patent: US2008/242596, 2008, A1. Location in patent: Page/Page column 15
[3] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 19, p. 5632 - 5635
[4] Bioorganic and Medicinal Chemistry Letters, 2009, vol. 19, # 24, p. 6877 - 6881
[5] ChemMedChem, 2010, vol. 5, # 6, p. 827 - 831

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester synthesis

18595-18-1
474330-54-6
Synthesis of 5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester from Methyl 3-amino-4-methylbenzoate

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Preparation Products And Raw materials

Raw materials

Methyl 3-amino-4-methylbenzoate 3-Amino-4-methylbenzoic acid 5-amino-2-bromo-4-methylbenzoic acid Methanol

Preparation Products

1H-Indazole-6-carboxylic acid, 5-broMo-, Methyl ester

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Suppliers

Global Suppliers ( 72)
Supplier Tel Email Country ProdList Advantage
Accela ChemBio Co.,Ltd. 021-50795510 4000665055 marketing@accelachem.com China 10972 64
Shanghai Topbiochem Technology Co., Ltd 021-58170097 info@topbiochem.com China 9509 58
SuZhou ShiYa Biopharmaceuticals, Inc. 86(512)5235 8471 17715136450 sales@shiyabiopharm.com China 4167 58
Shanghai MOF Chemical Tech Limited 13661494087 18964793018 sales@mof-chemicals.com China 292 55
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Nantong MYBio-pharm. Co., Ltd. 0513-85921823 18662920231 sales@ntminyanmedical.com China 4565 58
Shanghai Na Qian Chemical Technology Co. Ltd. 13598610367 13598610367 2841375912@qq.com China 3751 52
Cool Pharm, Ltd 021-60455363 18019463053 sales@coolpharm.com China 8455 58
Shanghai Boyners Pharm-Tech Co., Ltd. 13817873692 mkt@boynerspharm.com China 1707 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Supplier Advantage
Accela ChemBio Co.,Ltd. 64
Shanghai Topbiochem Technology Co., Ltd 58
SuZhou ShiYa Biopharmaceuticals, Inc. 58
Shanghai MOF Chemical Tech Limited 55
Bide Pharmatech Ltd. 60
Nantong MYBio-pharm. Co., Ltd. 58
Shanghai Na Qian Chemical Technology Co. Ltd. 52
Cool Pharm, Ltd 58
Shanghai Boyners Pharm-Tech Co., Ltd. 55
Shanghai YuanYe Biotechnology Co., Ltd. 60

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Spectrum

5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester(474330-54-6)1HNMR

474330-54-6 (5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester) Related Search:

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5-aMino-2-broMo-4-Methylbenzoic acid Methyl ester Methyl 5-aMino-2-broMo-4-Methylbenzoate Benzoic acid, 5-aMino-2-broMo-4-Methyl-, Methyl ester methyl 5-amino-2-bromo-4-methylbenzoate hydrochloride 474330-54-6