ChemicalBook >> CAS DataBase List >>3-Amino-4-methylbenzoic acid
3-Amino-4-methylbenzoic acid
- CAS No.
- 2458-12-0
- Chemical Name:
- 3-Amino-4-methylbenzoic acid
- Synonyms
- Nilotinib Related compound C;H-(3)ATL(4)-OH;Compound Fr14428;H-(3)ABZ(4-ME)-OH;Nilotinib USP RC C;RARECHEM AL BO 1039;3-Amino-4-methylbenz;3-Amino-p-toluylsure;3-AMINO-4-TOLUIC ACID;3-AMINO-P-TOLUIC ACID
- CBNumber:
- CB0736589
- Molecular Formula:
- C8H9NO2
- Molecular Weight:
- 151.16
- MDL Number:
- MFCD00007742
- MOL File:
- 2458-12-0.mol
- MSDS File:
- SDS
- TDS File:
- TDS
Last updated:2026-05-27 22:50:50
| Melting point | 164-168 °C (lit.) |
|---|---|
| Boiling point | 273.17°C (rough estimate) |
| Density | 1.2023 (rough estimate) |
| refractive index | 1.5810 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| pka | 4.61±0.10(Predicted) |
| form | Crystalline Powder |
| color | Pink to grayish |
| Water Solubility | Very soluble in water. |
| BRN | 2082449 |
| Stability | Hygroscopic |
| Major Application | peptide synthesis |
| InChI | 1S/C8H9NO2/c1-5-2-3-6(8(10)11)4-7(5)9/h2-4H,9H2,1H3,(H,10,11) |
| InChIKey | XKFIFYROMAAUDL-UHFFFAOYSA-N |
| SMILES | Cc1ccc(cc1N)C(O)=O |
| CAS DataBase Reference | 2458-12-0(CAS DataBase Reference) |
| FDA UNII | BU165505VM |
| NIST Chemistry Reference | 3-Amino-4-methylbenzoic acid(2458-12-0) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Gloves | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29224995 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
3-Amino-4-methylbenzoic acid price More Price(69)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0002108 | Nilotinib impurity C European Pharmacopoeia (EP) Reference Standard | 2458-12-0 | 20 mg | $171 | 2026-04-30 | Buy |
| Sigma-Aldrich | PHR2835 | Nilotinib Related compound C | 2458-12-0 | 50MG | $493 | 2026-04-30 | Buy |
| Sigma-Aldrich | A62809 | 3-Amino-4-methylbenzoic acid 99% | 2458-12-0 | 50g | $141 | 2026-04-30 | Buy |
| Sigma-Aldrich | 1463457 | Nilotinib Related Compound C | 2458-12-0 | 25MG | $1210 | 2026-04-30 | Buy |
| Sigma-Aldrich | Y0002108 | Nilotinib impurity C European Pharmacopoeia (EP) Reference Standard | 2458-12-0 | Y0002108 | $157 | 2024-03-01 | Buy |
3-Amino-4-methylbenzoic acid Chemical Properties, Uses, Production
Uses
3-Amino-4-methylbenzoic acid is used as a starting material to synthesize cyclopropamitosene compounds, which have potential antitumour activity. 3-Amino-4-methylbenzoic acid also has some partial herbicidal activity.
Chemical Properties
white to light yellow crystal powder
Uses
3-Amino-4-methylbenzoic acid, is a raw material used in synthesis. It is also used as an organic intermediate, Pharmaceutical intermediate.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
0.5 g of 3-nitro-4-methyl-benzoic acid (2.76 mmol, 1.0 eq.) was dissolved in 30 mL of methanol, 5% Pd/C was added and stirred vigorously for 3 hr. under hydrogen atmosphere. The catalyst was then filtered through a short silica gel column with ethyl acetate and the organic phase was concentrated in vacuum. 400 mg of 3-amino-4-methylbenzoic acid (2.65 mmol, 96%) was obtained as a pale yellow solid.
3-Amino-4-methylbenzoic acid Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global Suppliers ( 439)
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Changzhou Baokang Pharmaceutical & Chemical Co.,Ltd. | 0519-88787018 15261192718 | sales@baokangchem.com | China | 91 | 60 |
| Arizest(Shanghai)Pharmatech Co.,Ltd | 60753300-53010 13671599112 | geshi.zhuang@acebright.com | China | 97 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| future industrial shanghai co., ltd | 400-0066400 13621662912 | sales@jonln.com | China | 1989 | 65 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| TAIYUAN RHF CO.,LTD. | +86 351 7031519 | sales@RHFChem.com | China | 2334 | 56 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Beijing dtftchem Technology Co., Ltd. | 010-60275820 13031183356 | elainezt@sina.com | China | 1386 | 62 |
View Latest Price from 3-Amino-4-methylbenzoic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 3-Amino-4-methylbenzoic acid
2458-12-0
|
$97.67 | 25Kg/Drum | 99.00%HPLC | 9tons/month | Asia Chem I and E (Jiangsu) Co Ltd | |
 |
2026-09-16 | 3-Amino-4-methylbenzoic acid
2458-12-0
|
$75.00-100.00 | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | |
 |
2026-06-30 | 3-Amino-4-methylbenzoic acid
2458-12-0
|
1KG | 99.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd |
-
- 3-Amino-4-methylbenzoic acid
2458-12-0
- $97.67
- 99.00%HPLC
- Asia Chem I and E (Jiangsu) Co Ltd
-
- 3-Amino-4-methylbenzoic acid
2458-12-0
- $75.00-100.00
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
-
- 3-Amino-4-methylbenzoic acid
2458-12-0
- 99.0%
- Shaanxi Dideu New Materials Co. Ltd
2458-12-0 (3-Amino-4-methylbenzoic acid) Related Search:
3-Aminobenzoic acid
o-Toluic acid
4-Dimethylaminobenzoic acid
4-Amino-3-methylbenzoic acid
3-[(Aminoiminomethyl)amino]-4-methylbenzoic acid ethyl ester mononitrate
1of4
H-(3)ABZ(4-ME)-OH
H-(3)ATL(4)-OH
3-AMINO-P-TOLUIC ACID
3-AMINO-4-TOLUIC ACID
3-AMINO-4-METHYLBENZOIC ACID
Benzoic acid, 3-amino-4-methyl-
3-Amino-4-methylbenzoic
3-AMINO-4-METHYLBENZOATE(3-AMINO-P-TOLUIC ACID)
3-AMino-4-Methylbenzoic acid, 95+%
RARECHEM AL BO 1039
Benzoic acid, 3-amino-4-methyl- (9CI)
3-AMINO-4-METHYLBENZOIC ACID / 3-AMINO-P-TOLUIC ACID
2-Toluidine-4-carboxylic acid
4-Methyl-3-aminobenzoic acid
3-Amino-4-Methyl benzoic acic
3-Amino-4-methylbenzoic acid,99%
3-Amino-4-methylbenz
3-Amino-p-toluic acid (COOH=1)
3-Amino-p-toluic acid, 5-Carboxy-2-methylaniline
Nilotinib EP Impurity C
Nilotinib Impurity 26
3-Amino-4-methylbenzoic Acid >
Nilotinib USP RC C
3-Amino-p-toluylsure
3-Amino-4-methylbenzoicaci
3-Amino-4-methylbenzoic acid 2458-12-0
Nilotinib Hydrochloride Monohydrate Impurity C
Compound Fr14428
Nilotinib Impurity 18(Nilotinib EP Impurity C)
Nilotinib Hydrochloride Monohydrate EP Impurity C
Nilotinib EP Impurity C (Nilotinib USP Related Compound C)
Nilotinib Related compound C
2458-12-0
2458-12-8
Peptide Synthesis
Specialty Synthesis
Unnatural Amino Acid Derivatives
AMINE
Aromatic Amino Acids
Benzoic acid
Organic acids
Aromatic Carboxylic Acids, Amides, Anilides, Anhydrides & Salts
CARBOXYLICACID
Chemical intermediate for Nilotinib
bc0001
