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2-Chloro-7-Methoxyquinoline

CAS No.
49609-15-6
Chemical Name:
2-Chloro-7-Methoxyquinoline
Synonyms
2-Chloro-7-Methoxyquinoline;QUINOLINE, 2-CHLORO-7-METHOXY-
CBNumber:
CB12618060
Molecular Formula:
C10H8ClNO
Molecular Weight:
193.63
MDL Number:
MFCD13192242
MOL File:
49609-15-6.mol
MSDS File:
SDS
Last updated:2025-07-24 18:13:53

2-Chloro-7-Methoxyquinoline Properties

Melting point 97-98 °C
Boiling point 145 °C(Press: 0.6 Torr)
Density 1.267±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 0.65±0.50(Predicted)
Appearance Off-white to light brown Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

2-Chloro-7-Methoxyquinoline price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C632238 2-Chloro-7-methoxyquinoline 49609-15-6 10mg $45 2021-12-16 Buy
TRC C632238 2-Chloro-7-methoxyquinoline 49609-15-6 50mg $130 2021-12-16 Buy
TRC C632238 2-Chloro-7-methoxyquinoline 49609-15-6 100mg $200 2021-12-16 Buy
AK Scientific 6723AB 2-Chloro-7-methoxyquinoline 49609-15-6 100mg $341 2021-12-16 Buy
American Custom Chemicals Corporation HCH0363643 2-CHLORO-7-METHOXYQUINOLINE 95.00% 49609-15-6 5MG $501.77 2021-12-16 Buy
Product number Packaging Price Buy
C632238 10mg $45 Buy
C632238 50mg $130 Buy
C632238 100mg $200 Buy
6723AB 100mg $341 Buy
HCH0363643 5MG $501.77 Buy

2-Chloro-7-Methoxyquinoline Chemical Properties,Uses,Production

Synthesis

7-METHOXY-1H-QUINOLIN-2-ONE

23981-26-2

2-Chloro-7-Methoxyquinoline

49609-15-6

General procedure: 300 mg (1.9 mmol) of 7-methoxyquinolin-2(1H)-one was dissolved in 1.1 mL of phosphorus oxychloride (POCl3, 12 mmol) and the reaction was heated to reflux for 3 hours. Upon completion of the reaction, the reaction mixture was slowly poured into ice water, neutralized to neutral with saturated sodium bicarbonate (NaHCO3) solution and subsequently extracted with ethyl acetate. After treatment, the target product 2-chloro-7-methoxyquinoline was obtained in 98% yield. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 8.01 (d, J = 8.5 Hz, 1H), 7.68 (d, J = 8.9 Hz, 1H), 7.35 (d, J = 2.4 Hz, 1H), 7.25 (d, J = 8.3 Hz, 1H), 7.20 (dd, J = 8.9, 2.5 Hz, 1H), and 3.93 (s, 3H).

References

[1] Patent: WO2016/130968, 2016, A1. Location in patent: Page/Page column 183-184
[2] Patent: WO2014/85284, 2014, A1. Location in patent: Paragraph 00222

23981-26-2
49609-15-6
Synthesis of 2-Chloro-7-Methoxyquinoline from 7-METHOXY-1H-QUINOLIN-2-ONE

2-Chloro-7-Methoxyquinoline Preparation Products And Raw materials

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 33024 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29804 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Dayang Chem (Hangzhou) Co.,Ltd.
+86-0571-88938639 +8617705817739 info@dycnchem.com China 52846 58
Suzhou Victorypharm Co.,Ltd.
+86-13916956214 sales@victory-pharm.com China 1299 58
LEAP CHEM CO., LTD.
+86-852-30606658 19957148339; market18@leapchem.com China 24727 58
PT CHEM GROUP LIMITED
+86-85511178; peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49983 58
SUZHOU SENFEIDA CHEMICAL CO.,LTD
+86-0512-83500002 +8618662433356 3899766280@qq.com China 26362 58

View Lastest Price from 2-Chloro-7-Methoxyquinoline manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2-Chloro-7-Methoxyquinoline pictures 2020-01-08 2-Chloro-7-Methoxyquinoline
49609-15-6
US $2.00 / KG 1KG 98% 100g , 1kg, 5kg , 50kg Career Henan Chemical Co
2-Chloro-7-Methoxyquinoline QUINOLINE, 2-CHLORO-7-METHOXY- 49609-15-6