DH 97
- CAS No.
- 343263-95-6
- Chemical Name:
- DH 97
- Synonyms
- DH 97;N-PENTANOYL-2-BENZYLTRYPTAMINE;N-[2-(2-benzyl-1H-indol-3-yl)ethyl]pentanamide;1-Pentanone,1-[3-(2-aminoethyl)-2-(phenylmethyl)-1H-indol-1-yl]-
- CBNumber:
- CB1270248
- Molecular Formula:
- C22H26N2O
- Molecular Weight:
- 334.46
- MDL Number:
- MFCD02262121
- MOL File:
- 343263-95-6.mol
- MSDS File:
- SDS
- TDS File:
- TDS
DH 97 price More Price(19)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 29522 | DH 97 ≥98% | 343263-95-6 | 1mg | $41 | 2026-04-30 | Buy |
| Cayman Chemical | 29522 | DH 97 ≥98% | 343263-95-6 | 5mg | $108 | 2026-04-30 | Buy |
| Cayman Chemical | 29522 | DH 97 ≥98% | 343263-95-6 | 10mg | $157 | 2026-04-30 | Buy |
| Cayman Chemical | 29522 | DH 97 ≥98% | 343263-95-6 | 25mg | $341 | 2026-04-30 | Buy |
| ChemScene | CS-0144498 | DH97-7 | 343263-95-6 | 1mg | $77 | 2026-06-04 | Buy |
DH 97 Chemical Properties, Uses, Production
Description
DH 97 is an antagonist of melatonin receptor 2 (MT2; Kis = 252 and 1,100 for human MT2 and MT1 receptors, respectively).
Uses
DH97 is a potent melatonin receptor 2 (MT2) antagonist with Ki values of 252 nM and 1100 nM for MT2 and MT1, respectively[1].
Definition
ChEBI: N-[2-[2-(phenylmethyl)-1H-indol-3-yl]ethyl]pentanamide is a member of indoles.
Biological Activity
A relatively potent MT 2 melatonin receptor antagonist (pK i value = 8.03), displaying 89- and 229-fold selectivity over MT 1 and GPR50 (melatonin-related orphan receptor) respectively.
IC 50
MT2: 252 nM (Ki); MT1: 1100 nM (Ki)
References
[1] O Nosjean, et al. Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2. Biochem Pharmacol. 2001 Jun 1;61(11):1369-79. DOI:10.1016/s0006-2952(01)00615-3
DH 97 Preparation Products And Raw materials
Raw materials
Preparation Products
DH 97 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11123 | 58 |
| TargetMol Chemicals Inc. | 4008200310 15002144251 | marketing@tsbiochem.com | China | 24951 | 58 |
| Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 5985 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 11963 | 58 |
