1(2H)-Phthalazinone
- CAS No.
- 119-39-1
- Chemical Name:
- 1(2H)-Phthalazinone
- Synonyms
- phthalazinone;Phthalazin-1(2H)-one;PHTHALAZONE;1-Phthalazinone;PTLZ;Pthalazone;1-phthalazinol;Phthalazone>1,2H-PHTHALAZONE;phthalazin-1-one
- CBNumber:
- CB1282098
- Molecular Formula:
- C8H6N2O
- Molecular Weight:
- 146.15
- MDL Number:
- MFCD00006892
- MOL File:
- 119-39-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 183-185 °C(lit.) |
|---|---|
| Boiling point | 337°C(lit.) |
| Density | 1.2312 (rough estimate) |
| refractive index | 1.4900 (estimate) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| pka | 12.29±0.20(Predicted) |
| form | Crystalline Powder |
| color | Off-white to pale yellow |
| BRN | 3654 |
| InChI | InChI=1S/C8H6N2O/c11-8-7-4-2-1-3-6(7)5-9-10-8/h1-5H,(H,10,11) |
| InChIKey | IJAPPYDYQCXOEF-UHFFFAOYSA-N |
| SMILES | C1(=O)C2=C(C=CC=C2)C=NN1 |
| CAS DataBase Reference | 119-39-1(CAS DataBase Reference) |
| FDA UNII | 463ZJB0EI2 |
| EPA Substance Registry System | 1(2H)-Phthalazinone (119-39-1) |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319 | |||||||||
| Precautionary statements | P501-P270-P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313-P301+P312+P330 | |||||||||
| PPE | dust mask type N95 (US), Eyeshields, Faceshields, Gloves | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22-68-36/37/38 | |||||||||
| Safety Statements | 22-24/25-36/37/39-26 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | TH9185000 | |||||||||
| TSCA | TSCA listed | |||||||||
| HazardClass | IRRITANT | |||||||||
| HS Code | 29339990 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| Hazard Classifications | Acute Tox. 4 Oral | |||||||||
| Hazardous Substances Data | 119-39-1(Hazardous Substances Data) | |||||||||
| Toxicity | mouse,LD50,intravenous,180mg/kg (180mg/kg),U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#00139, | |||||||||
| REACH Registrations | Active | |||||||||
| NFPA 704 |
|
1(2H)-Phthalazinone price More Price(42)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | P39001 | Phthalazone 99% | 119-39-1 | 5g | $58.2 | 2026-04-30 | Buy |
| Sigma-Aldrich | P39001 | Phthalazone 99% | 119-39-1 | 100g | $362 | 2023-06-20 | Buy |
| TCI Chemical | P1179 | Phthalazone >98.0%(GC) | 119-39-1 | 25g | $27 | 2026-04-30 | Buy |
| TCI Chemical | P1179 | Phthalazone >98.0%(GC) | 119-39-1 | 500g | $189 | 2026-04-30 | Buy |
| Usbiological | 286434 | 1(2H)-Phthalazinone Asreported | 119-39-1 | 25g | $347 | 2026-06-03 | Buy |
1(2H)-Phthalazinone Chemical Properties, Uses, Production
Chemical Properties
Off-white to pale yellow crystalline powder
Uses
Phthalazone is a remarkable scaffold in drug discovery. Also, functions as an oxidative metabolic pathway of lenvatinib mediated by aldehyde oxidase.
Definition
ChEBI: Phthalazin-1(2H)-one is a member of phthalazines.
General Description
Pale yellow crystals. Insoluble in water.
Air & Water Reactions
Insoluble in water.
Fire Hazard
Flash point data for 1(2H)-Phthalazinone are not available. 1(2H)-Phthalazinone is probably combustible.
Purification Methods
Phthalazone crystallises from H2O or EtOH and sublimes in vacuo. [Beilstein 24 H 142, 24 24 III/IV 400.]
1(2H)-Phthalazinone Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jiangsu Baiaoxinkang Pharmaceutical Technology Co. , Ltd. | 18015077019 18015077019 | jwang@bioscenepharma.com | China | 105 | 58 |
| NingBo Sialon Chem Co., Ltd. | 0574-28809768 18658497215 | sales@newsialon.com | China | 40 | 58 |
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Meryer (Shanghai) Chemical Technology Co., Ltd. | 4006356688 18621169109 | market03@meryer.com | China | 40202 | 62 |
| INTATRADE GmbH | +49 3493/605464 | sales@intatrade.de | Germany | 3563 | 66 |
| TCI (Shanghai) Development Co., Ltd. | 021-67121386 | Sales-CN@TCIchemicals.com | China | 24512 | 81 |
| Energy Chemical | 400-0056266 | sales8178@energy-chemical.com | China | 44850 | 61 |
| JinYan Chemicals(ShangHai) Co.,Ltd. | 13817811078 | sales@jingyan-chemical.com | China | 9963 | 60 |
| Jia Xing Isenchem Co.,Ltd | 0573-85285100 18627885956 | isenchem@163.com | China | 9389 | 66 |
| Shanghai Longsheng chemical Co.,Ltd. | 58099637 13585536065 | sales@shlschem.com | China | 9880 | 59 |
View Latest Price from 1(2H)-Phthalazinone manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-09-17 | 1(2H)-Phthalazinone
119-39-1
|
$5.00 | 1kg | ≥98% | 50mt/year | Jinan Finer Chemical Co., Ltd | |
 |
2026-06-30 | 1(2H)-Phthalazinone
119-39-1
|
1kg | 98% | 1000kg | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2025-07-25 | phthalazin-1(2H)-one
119-39-1
|
2mg | 99% HPLC | 20kg | Anko Intermational Trade Limited
|
-
- 1(2H)-Phthalazinone
119-39-1
- $5.00
- ≥98%
- Jinan Finer Chemical Co., Ltd
-
- 1(2H)-Phthalazinone
119-39-1
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- phthalazin-1(2H)-one
119-39-1
- $0.00
- 99% HPLC
- Anko Intermational Trade Limited
