Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1-Bromo-4-chloro-2-fluorobenzene

1-Bromo-4-chloro-2-fluorobenzene

1-Bromo-4-chloro-2-fluorobenzene Structure
1-Bromo-4-chloro-2-fluorobenzene structure
CAS No.
1996-29-8
Chemical Name:
1-Bromo-4-chloro-2-fluorobenzene
Synonyms
1-Bromo-4-chloro-2-f;2-Fluoro-4-chloro broMo;1-Bromo-4-chloro-2-fluorob;1-Bromo-4-chloro-2-fluorobe;2-fluoro-4-chlorobroMobezene;2-FLUORO-4-CHLOROBROMOBENZENE;2-BROMO-5-CHLOROFLUOROBENZENE;4-CHLORO-2-FLUORO BROMOBENZENE;3-fluoro-4-bromo-chlorobenzene;2-fluoro-4-chloro-fluorobenzene
CBNumber:
CB1298503
Molecular Formula:
C6H3BrClF
Molecular Weight:
209.44
MDL Number:
MFCD00079708
MOL File:
1996-29-8.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:25:33
Product description Number Pack Size Price
1-Bromo-4-chloro-2-fluorobenzene 98% 532703 25g $94.9
1-Bromo-4-chloro-2-fluorobenzene >98.0%(GC) B2724 5g $21
1-Bromo-4-chloro-2-fluorobenzene >98.0%(GC) B2724 25g $61
1-Bromo-4-chloro-2- fluorobenzene, min. 98% min.98% 09-0037 25g $36
1-Bromo-4-chloro-2- fluorobenzene, min. 98% min.98% 09-0037 100g $95
More product size
Request For Quotation

1-Bromo-4-chloro-2-fluorobenzene Properties

Boiling point 91-92 °C/20 mmHg (lit.)
Density 1.678 g/mL at 25 °C (lit.)
refractive index n20/D 1.556(lit.)
Flash point 198 °F
storage temp. Sealed in dry,Room Temperature
form Liquid
Specific Gravity 1.678
color Clear colorless to pale yellow
Water Solubility INSOLUBLE
BRN 2081083
InChI InChI=1S/C6H3BrClF/c7-5-2-1-4(8)3-6(5)9/h1-3H
InChIKey FPNVMCMDWZNTEU-UHFFFAOYSA-N
SMILES C1(Br)=CC=C(Cl)C=C1F
CAS DataBase Reference 1996-29-8(CAS DataBase Reference)
UNSPSC Code 12352100
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H227-H315-H319-H335
Precautionary statements  P210e-P261-P280a-P305+P351+P338-P405-P501a-P210-P264-P280-P302+P352+P332+P313+P362+P364-P403+P235-P501
PPE Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  37/39-26-24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29039990
Storage Class 10 - Combustible liquids
REACH Registrations Active
NFPA 704
0
2 0

1-Bromo-4-chloro-2-fluorobenzene price More Price(67)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 532703 1-Bromo-4-chloro-2-fluorobenzene 98% 1996-29-8 25g $94.9 2023-01-07 Buy
TCI Chemical B2724 1-Bromo-4-chloro-2-fluorobenzene >98.0%(GC) 1996-29-8 5g $21 2026-04-30 Buy
TCI Chemical B2724 1-Bromo-4-chloro-2-fluorobenzene >98.0%(GC) 1996-29-8 25g $61 2026-04-30 Buy
Strem Chemicals 09-0037 1-Bromo-4-chloro-2- fluorobenzene, min. 98% min.98% 1996-29-8 25g $36 2026-04-30 Buy
Strem Chemicals 09-0037 1-Bromo-4-chloro-2- fluorobenzene, min. 98% min.98% 1996-29-8 100g $95 2026-04-30 Buy
Product number Packaging Price Buy
532703 25g $94.9 Buy
B2724 5g $21 Buy
B2724 25g $61 Buy
09-0037 25g $36 Buy
09-0037 100g $95 Buy

1-Bromo-4-chloro-2-fluorobenzene Chemical Properties,Uses,Production

Chemical Properties

CLEAR COLORLESS TO PALE YELLOW LIQUID

Uses

A 2,4-dihalofluorobenzene derivative with antibacterial and antifungal activities.

Uses

1-Bromo-4-chloro-2-fluorobenzene may be used in the preparation of benzonorbornadiene derivative. It may also be used as a starting material in the multi-step synthesis of AZD3264, an IKK2 (inhibitor of nuclear factor κ-B kinase-2) inhibitor.

General Description

1-Bromo-4-chloro-2-fluorobenzene is a polyhalo substituted benzene. It undergoes Suzuki coupling with 2-cyanoarylboronic esters to form the corresponding biphenyls. These biphenyls are the precursors for synthesizing 6-substituted phenanthridines. The enthalpy of vaporization at boiling point (467.15K) of 1-bromo-4-chloro-2-fluorobenzene is 40.737kjoule/mol.

Pharmaceutical Applications

1-Bromo-4-chloro-2-fluorobenzene serves as a crucial building block for synthesizing brilanestrant, a selective estrogen receptor degrader used in the treatment of breast cancer. It controls the potency on the degradation of estrogen receptor 1 (ERα), demonstrating an effective concentration of 0.7 nM.

1-Bromo-4-chloro-2-fluorobenzene synthesis

57946-56-2
1996-29-8
Synthesis of 1-Bromo-4-chloro-2-fluorobenzene from 4-Chloro-2-fluoroaniline

1-Bromo-4-chloro-2-fluorobenzene Preparation Products And Raw materials

Raw materials

4-Chloro-2-fluoroaniline

Preparation Products

1-Boc-4-(4-chloro-2-fluorophenyl)piperazine 1-Pyrrolidinecarboxylic acid, 3-(2-bromo-5-chlorophenoxy)-, 1,1-dimethylethyl ester, (3S)- 4-Chloro-2-fluorophenylboronic acid

1-Bromo-4-chloro-2-fluorobenzene Suppliers

Global( 392)Suppliers
Supplier Tel Email Country ProdList Advantage
Suzhou Actchem Co., Ltd.
+8618762124502 actchem@qq.com China 27 58
Hebei Chuanghai Biotechnology Co., Ltd 		+8615350571055 Sibel@chuanghaibio.com China 8738 58
Hebei Chuanghai Biotechnology Co,.LTD 		+86-86-13131129325 +8613131129325 sales1@chuanghaibio.com China 5220 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 20120 58
Springchem New Material Technology Co.,Limited 		+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29640 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-2158073036 info@dakenam.com China 14026 58
Hi-Tech Chemistry Corp 		0519-86626038 yuhh@hitechem.com CHINA 810 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21585 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3009 60
Supplier Advantage
Suzhou Actchem Co., Ltd.
58
Hebei Chuanghai Biotechnology Co., Ltd 		58
Hebei Chuanghai Biotechnology Co,.LTD 		58
Henan Fengda Chemical Co., Ltd 		58
Springchem New Material Technology Co.,Limited 		57
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Hi-Tech Chemistry Corp 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60

View Lastest Price from 1-Bromo-4-chloro-2-fluorobenzene manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Bromo-4-chloro-2-fluorobenzene pictures 2026-07-09 1-Bromo-4-chloro-2-fluorobenzene
1996-29-8
 $1.00-100.00 1KG 99% Henan Fengda Chemical Co., Ltd
1-Bromo-4-chloro-2-fluorobenzene pictures 2026-05-28 1-Bromo-4-chloro-2-fluorobenzene
1996-29-8
 $10.00 1KG 99.% 10 ton Hebei Chuanghai Biotechnology Co,.LTD
1-Bromo-4-chloro-2-fluorobenzene pictures 2026-03-20 1-Bromo-4-chloro-2-fluorobenzene
1996-29-8
 1KG 99% 20 mt Hebei Chuanghai Biotechnology Co., Ltd

1-Bromo-4-chloro-2-fluorobenzene Spectrum

1-Bromo-4-chloro-2-fluorobenzene(1996-29-8)IR

1996-29-8(1-Bromo-4-chloro-2-fluorobenzene)Related Search:

BCDMH Chlorobromoisocyanurate 4-Bromofluorobenzene 5-CHLORO-2,3-DIBROMO-1-FLUOROBENZENE Difluorochloromethane
1-BROMO-4-CHLORO-2-FLUORO-5-METHOXY-BENZENE Bromochloromethane 1-BROMO-4-CHLORO-2,3,5,6-TETRAFLUOROBENZENE 4-Bromo-2-chloro-1-fluorobenzene 6-Bromo-3-chloro-2-fluorophenylboronic acid
2-BROMO-4-CHLORO-6-FLUOROANISOLE 1,2-DIFLUORO-4,5-DIMETHOXYBENZENE 4-Bromo-1-chloro-2-fluorobenzene 1-Bromo-2-chloro-4-fluorobenzene 5-Bromo-3-chloro-2-fluorophenylboronic acid
Bromine 2-Bromo-1-chloro-4-fluorobenzene 1-Bromo-3-chloro-5-fluorobenzene

1of4

1-Bromo-4-chloro-2-fluorobenzene 97% 4-CHLORO-2-FLUORO BROMOBENZENE 1-Bromo-4-chloro-2-fluorobenzene97% 2-BROMO-5-CHLORO-1-FLUOROBENZENE 2-BROMO-5-CHLOROFLUOROBENZENE 2-FLUORO-4-CHLOROBROMOBENZENE 1-BROMO-4-CHLORO-2-FLUOROBENZENE 2-tert-Butyl-4-(dicyanomethylene)-6-[2-(1,1,7,7-tetramethyljulolidin-9-yl)vinyl]-4H-pyran [This reagent can be used without further purification for display device research, etc.] 1-Bromo-4-chloro-2-f 4-Chloro-2-fluorobromobenzene 97% 2-Fluoro-4-chloro broMo 2-fluoro-4-chlorobroMobezene 2-fluoro-4-chloro-fluorobenzene 3-fluoro-4-bromo-chlorobenzene Benzene, 1-bromo-4-chloro-2-fluoro- 2-tert-Butyl-4-(dicyanomethylene)-6-[2-(1,1,7,7-tetramethyljulolidin-9-yl)vinyl]-4H-pyran [This re 1-Bromo-4-chloro-2-fluorobenzene > 1-Bromo-4-chloro-2-fluorob 1-Bromo-4-chloro-2-fluorobenzene ISO 9001：2015 REACH 1-Bromo-4-chloro-2-fluorobe 1996-29-8 20005207-00-6 BrC6H3ClF HALIDE Organic Building Blocks Halogenated Hydrocarbons Building Blocks Aryl C6 Fluorine series Building Blocks Chemical Synthesis Fluorinated Building Blocks Halogenated Hydrocarbons Organic Building Blocks Organic Fluorinated Building Blocks Other Fluorinated Organic Building Blocks Aryl Fluorinated Building Blocks Aryl Halogenated Hydrocarbons Bromine Compounds Chlorine Compounds Fluorine Compounds Aromatics Aromatic Halides (substituted) C6