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ChemicalBook >> CAS DataBase List >>1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Structure
1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid structure
CAS No.
1144504-35-7
Chemical Name:
1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid
Synonyms
PQCA;MSD-M1PAM;PQCA, 10 mM in DMSO;1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid;4H-Quinolizine-3-carboxylic acid, 1-[[4-cyano-4-(2-pyridinyl)-1-piperidinyl]methyl]-4-oxo-
CBNumber:
CB13100995
Molecular Formula:
C22H20N4O3
Molecular Weight:
388.42
MDL Number:
MFCD26403374
MOL File:
1144504-35-7.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-14 16:49:18
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1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Properties

Boiling point 708.5±60.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : 10 mg/mL (25.75 mM; ultrasonic and warming and heat to 80°C)
form Solid
pka 1.83±0.20(Predicted)
color White to yellow

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 41358 MSD-M1PAM ≥98% 1144504-35-7 500μg $57 2026-04-30 Buy
Cayman Chemical 41358 MSD-M1PAM ≥98% 1144504-35-7 1mg $102 2026-04-30 Buy
Biosynth UVB50435 PQCA 1144504-35-7 25mg $1382.75 2026-06-05 Buy
Biosynth UVB50435 PQCA 1144504-35-7 50mg $1923.5 2026-06-05 Buy
ChemScene CS-0065722 PQCA 99.96% 1144504-35-7 1mg $103 2026-06-04 Buy
Product number Packaging Price Buy
41358 500μg $57 Buy
41358 1mg $102 Buy
UVB50435 25mg $1382.75 Buy
UVB50435 50mg $1923.5 Buy
CS-0065722 1mg $103 Buy

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Chemical Properties, Uses, Production

Uses

PQCA is a highly selective and potent muscarinic M1 receptor positive allosteric modulator. PQCA is a novel M1 muscarinic potentiator that improves cognition without adverse effects compared to donepezil and xanomeline in rhesus monkey.

in vivo

PQCA (3-30 mg/kg; oral administration; single- or pair-housed male rhesus monkeys) treatment attenuates the scopolamine deficits in PAL and CPT tasks. Blockade of muscarinic signaling by scopolamine produces significant impairments in both tasks[1].

Animal Model:Ten single- or pair-housed male rhesus monkeys (6-10 years old; 5.2-10.5 kg) with scopolamine[1]
Dosage:3 mg/kg, 10 mg/kg, or 30 mg/kg
Administration:Oral administration
Result:Attenuated the scopolamine deficits in paired-associates learning (PAL) and the continuous-performance task (CPT).

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Suppliers

Global Suppliers ( 20)
Supplier Tel Email Country ProdList Advantage
BOC Sciences 1-631-485-4226; 16314854226 info@bocsci.com United States 9920 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 18149758185 18149758185 sales-cpd@caerulumpharma.com China 3493 58
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
ShangHai ChuanQian Chemcial Technique Centre 15869524721 3525679403@qq.com China 4565 58
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 5985 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Beijing Boorsen Biotechnology Co., Ltd 400-901-9800 18611424007 cis@bioss.com.cn China 9185 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 6206333 13167063860 anhua.mao@aladdin-e.com China 43586 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 29874 58
Supplier Advantage
BOC Sciences 65
ShangHai Caerulum Pharma Discovery Co., Ltd. 58
Shanghai YuanYe Biotechnology Co., Ltd. 60
TargetMol Chemicals Inc. 58
ShangHai ChuanQian Chemcial Technique Centre 58
Nantong QuanYi Biotechnology Co., Ltd 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Beijing Boorsen Biotechnology Co., Ltd 58
Shanghai Aladdin Biochemical Technology Co.,Ltd. 58
TargetMol Chemicals Inc. 58

View Latest Price from 1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PQCA pictures 2026-07-14 PQCA
1144504-35-7
 $47.00-202.00 99.88% 10g TargetMol Chemicals Inc.
PQCA pictures 2026-07-14 PQCA
1144504-35-7
 $47.00-202.00 99.88% 10g TargetMol Chemicals Inc.
  • PQCA pictures
  • PQCA
    1144504-35-7
  • $47.00-202.00
  • 99.88%
  • TargetMol Chemicals Inc.
  • PQCA pictures
  • PQCA
    1144504-35-7
  • $47.00-202.00
  • 99.88%
  • TargetMol Chemicals Inc.

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid Spectrum

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid(1144504-35-7)1HNMR

1144504-35-7 (1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid) Related Search:

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1of2

1-((4-cyano-4-(pyridin-2-yl)piperidin-1-yl)methyl)-4-oxo-4H-quinolizine-3-carboxylic acid PQCA 4H-Quinolizine-3-carboxylic acid, 1-[[4-cyano-4-(2-pyridinyl)-1-piperidinyl]methyl]-4-oxo- PQCA, 10 mM in DMSO MSD-M1PAM 1144504-35-7