2-FLUORONICOTINIC ACID METHYL ESTER
- CAS No.
- 446-26-4
- Chemical Name:
- 2-FLUORONICOTINIC ACID METHYL ESTER
- Synonyms
- methyl 2-fluoronicotinate;2-fluoronicotin methyl ester;2-FLUORONICOTINIC ACID METHYL ESTER;Methyl 2-fluoro-3-pyridinecarboxylate;Methyl 2-fluoropyridine-3-carboxylate;3-Pyridinecarboxylicacid, 2-fluoro-, methyl ester;2-FLUORONICOTINIC ACID METHYL ESTER ISO 9001：2015 REACH
- CBNumber:
- CB1327933
- Molecular Formula:
- C7H6FNO2
- Molecular Weight:
- 155.13
- MDL Number:
- MFCD03095072
- MOL File:
- 446-26-4.mol
- MSDS File:
- SDS
| Melting point | 22-26 °C |
|---|---|
| Boiling point | 75 °C/5 mmHg |
| Density | 1.243±0.06 g/cm3(Predicted) |
| Flash point | 110 °C |
| storage temp. | Inert atmosphere,Room Temperature |
| pka | -2.47±0.10(Predicted) |
| form | liquid |
| Appearance | Colorless to light yellow Liquid |
| InChIKey | PJNHJXKXBSOLBH-UHFFFAOYSA-N |
| CAS DataBase Reference | 446-26-4(CAS DataBase Reference) |
| UNSPSC Code | 12352100 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| WGK Germany | 3 |
| HS Code | 2933399990 |
2-FLUORONICOTINIC ACID METHYL ESTER price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 701904 | Methyl 2-fluoropyridine-3-carboxylate 97% | 446-26-4 | 1g | $163 | 2023-06-20 | Buy |
| TRC | M305530 | Methyl2-fluoronicotinate | 446-26-4 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | M305530 | Methyl2-fluoronicotinate | 446-26-4 | 1g | $75 | 2021-12-16 | Buy |
| Frontier Specialty Chemicals | F13032 | Methyl 2-fluoropyridine-3-carboxylate 98% | 446-26-4 | 25g | $140 | 2021-12-16 | Buy |
| Matrix Scientific | 072665 | 2-Fluoronicotinic acid methyl ester 95+% | 446-26-4 | 25g | $183 | 2021-12-16 | Buy |
2-FLUORONICOTINIC ACID METHYL ESTER Chemical Properties,Uses,Production
Synthesis
40134-18-7
446-26-4
GENERAL METHOD: To a solution of methyl 2-chloronicotinate (1.00 g, 6.76 mmol) in DMSO (33.8 mL) was added CsF (2.053 g, 13.51 mmol) at room temperature. The reaction mixture was stirred at 110 °C for 20 h in air. Upon completion of the reaction, the reaction mixture was quenched with ice water and extracted with EtOAc (3 × 20 mL). The organic layers were combined, washed sequentially with water and saturated brine, dried over anhydrous Na2SO4, filtered and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography (eluent: hexane/EtOAc gradient elution) to afford methyl 2-fluoronicotinate (0.639 g, 4.86 mmol, 71.9% yield) as a colorless oil. The synthesis of compounds 3B'-8B' was carried out with reference to the preparation steps of 2B'.
References
[1] Tetrahedron Letters, 2015, vol. 56, # 44, p. 6043 - 6046
2-FLUORONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29734 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
| Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10406 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8826 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
View Lastest Price from 2-FLUORONICOTINIC ACID METHYL ESTER manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-02-23 | 2-FLUORONICOTINIC ACID METHYL ESTER
446-26-4
|
US $0.00 / KG | 1KG | 98.3% | 100 tons | Honest Joy Holdings Limited | |
 |
2021-08-12 | 2-FLUORONICOTINIC ACID METHYL ESTER
446-26-4
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd | |
 |
2019-07-06 | 2-FLUORONICOTINIC ACID METHYL ESTER
446-26-4
|
US $1.00 / kg | 1kg | 99% | Customized | Career Henan Chemical Co |
-
- 2-FLUORONICOTINIC ACID METHYL ESTER
446-26-4
- US $0.00 / KG
- 98.3%
- Honest Joy Holdings Limited
-
- 2-FLUORONICOTINIC ACID METHYL ESTER
446-26-4
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
-
- 2-FLUORONICOTINIC ACID METHYL ESTER
446-26-4
- US $1.00 / kg
- 99%
- Career Henan Chemical Co
