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2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER structure

CAS No.: 884494-84-2

Chemical Name:: 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER

Synonyms: Methyl 2-Fluoro-4-iodonicotinate;2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER;Methyl 2-Fluoro-4-iodopyridin-3-ylcarbanate;Methyl 2-fluoro-4-iodopyridine-3-carboxylate;2-Fluoro-4-iodo-3-pyridinecarboxylic acid methyl ester;3-PYRIDINECARBOXYLIC ACID, 2-FLUORO-4-IODO-,METHYL ESTER;Methyl 2-fluoro-4-iodopyridine-3-carboxylate, 2-Fluoro-4-iodo-3-(methoxycarbonyl)pyridine

CBNumber:: CB6468022

Molecular Formula:: C7H5FINO2

Molecular Weight:: 281.02

MDL Number:: MFCD04972401

MOL File:: 884494-84-2.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:54

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2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER Properties

Boiling point	287℃
Density	1.913
Flash point	127℃
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
pka	-3.86±0.18(Predicted)
Appearance	White to off-white Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302+H312+H332-H315-H319-H335
Precautionary statements	P280
HS Code	2933399990

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER price More Price(33)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	F598808	2-Fluoro-4-iodonicotinicacidmethylester	884494-84-2	250mg	$75	2021-12-16	Buy
TRC	F598808	2-Fluoro-4-iodonicotinicacidmethylester	884494-84-2	500mg	$115	2021-12-16	Buy
Frontier Specialty Chemicals	Y14228	Methyl2-fluoro-4-iodopyridine-3-carboxylate 98%	884494-84-2	5g	$120	2021-12-16	Buy
SynQuest Laboratories	4H23-K-X2	Methyl 2-fluoro-4-iodonicotinate	884494-84-2	250mg	$48	2021-12-16	Buy
Apolloscientific	PC49357	Methyl2-fluoro-4-iodonicotinate	884494-84-2	1g	$68	2021-12-16	Buy

Product number	Packaging	Price	Buy
F598808	250mg	$75	Buy
F598808	500mg	$115	Buy
Y14228	5g	$120	Buy
4H23-K-X2	250mg	$48	Buy
PC49357	1g	$68	Buy

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER Chemical Properties,Uses,Production

Synthesis

884494-51-3

18107-18-1

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER

884494-84-2

GENERAL STEPS: 2-Fluoro-4-iodonicotinic acid (5.13 g) was dissolved in a solvent mixture of ether (25 mL) and methanol (25 mL) under nitrogen protection. To this solution was slowly added a 10% hexane solution of trimethylsilylated diazomethane (32.9 g). The reaction mixture was stirred at room temperature for 3 hours. Upon completion of the reaction, the reaction solution was concentrated and the resulting residue was purified by silica gel column chromatography (eluent: hexane-ethyl acetate gradient) to afford methyl 2-fluoro-4-iodonicotinate (5.3 g). The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 3.94 (3H, s), 7.98 (1H, dd, J = 5.3, 1.1 Hz), 8.07 (1H, dd, J = 5.3, 0.8 Hz).

References

[1] Patent: EP2921480, 2015, A1. Location in patent: Paragraph 0391; 0392
[2] Patent: WO2016/95204, 2016, A1. Location in patent: Page/Page column 62; 63

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

2-FLUORO-4-IODONICOTINIC ACID (TRIMETHYLSILYL)DIAZOMETHANE

Preparation Products

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER Suppliers

Global( 80)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	+8613336195806	sales@capot.com	China	29734	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29855	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49975	58
Neostar United (Changzhou) Industrial Co., Ltd.	+86-0519-85551759 +8613506123987	marketing1@neostarunited.com	China	8826	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52846	58
CD Chemical Group Limited	+8615986615575	info@codchem.com	China	20342	58
changzhou huayang technology co., ltd	+8615250961469	2571773637@qq.com	China	9644	58
Nanjing Hengbei Chemicals Co., Ltd.	+86-25-58393656	sales@hengbeichem.cn	China	6854	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
career henan chemical co	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Neostar United (Changzhou) Industrial Co., Ltd.	58
SIMAGCHEM CORP	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
CD Chemical Group Limited	58
changzhou huayang technology co., ltd	58
Nanjing Hengbei Chemicals Co., Ltd.	58

View Lastest Price from 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 884494-84-2	US $1.00 / kg	1kg	98%	200KG	Career Henan Chemical Co

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER
884494-84-2
US $1.00 / kg
98%
Career Henan Chemical Co

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER Spectrum

2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER(884494-84-2)¹HNMR

884494-84-2(2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER)Related Search:

Iodine pentafluoride 2-FLUORONICOTINIC ACID METHYL ESTER 4-IODO-2-FLUORO-3-FORMYLPYRIDINE 4-IODONICOTINIC ACID 2-FLUORO-3-(HYDROXYMETHYL)-4-IODOPYRIDINE

2-Fluoronicotinic acid 2-FLUORO-4-IODO-3-PICOLINE 2-Fluoro-3-iodopyridine 2-FLUORO-3-FORMYLPYRIDINE 2-FLUORO-3-(HYDROXYMETHYL)PYRIDINE

2-FLUORO-4-IODONICOTINIC ACID 4-Iodo-3-methylpyridine 2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER

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2-FLUORO-4-IODONICOTINIC ACID METHYL ESTER 3-PYRIDINECARBOXYLIC ACID, 2-FLUORO-4-IODO-,METHYL ESTER Methyl 2-fluoro-4-iodopyridine-3-carboxylate Methyl 2-fluoro-4-iodopyridine-3-carboxylate, 2-Fluoro-4-iodo-3-(methoxycarbonyl)pyridine Methyl 2-Fluoro-4-iodopyridin-3-ylcarbanate 2-Fluoro-4-iodo-3-pyridinecarboxylic acid methyl ester Methyl 2-Fluoro-4-iodonicotinate 884494-84-2 C7H5FINO2 Boronic Acid Heterocyclic Compounds