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IRL-1620

CAS No.
142569-99-1
Chemical Name:
IRL-1620
Synonyms
Sovateltide;IRL-1620;SPI-1620;IRL-1620, HUMAN;28: PN: WO2007112069 SEQID;M.W. 1820.97 C86H117N17O27;SUC-[GLU9, ALA11,15]-ENDOTHELIN-1 (8-21);N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21);ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15];SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21)
CBNumber:
CB1348183
Molecular Formula:
C86H117N17O27
Molecular Weight:
1820.95
MDL Number:
MFCD00214284
MOL File:
142569-99-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-07-27 17:00:41

IRL-1620 Properties

Boiling point 2096.6±65.0 °C(Predicted)
Density 1.347±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Soluble in DMSO
form powder
pka 3.39±0.10(Predicted)
color white
Water Solubility Soluble in water (0.5 mg/ml)
Sequence Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp-OH
InChIKey DXPHNGAMYPPTBJ-DPDKTXOSNA-N
FDA UNII 11X778QIZS

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H332-H302-H312
Precautionary statements  P264-P270-P301+P312-P330-P501-P280-P302+P352-P312-P322-P363-P501-P261-P271-P304+P340-P312
WGK Germany  3

IRL-1620 price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 255523 IRL-1620 Asreported 142569-99-1 500ug $466 2026-06-03 Buy
Biosynth PED-4285-V Suc-[Glu9,Ala11,15]-Endothelin-1 (8-21) 142569-99-1 0.5mg $549.71 2026-06-04 Buy
Biosynth FS108425 Succinyl-(Glu9,Ala11·15)-Endothelin-1 (8-21) 142569-99-1 1mg $162.25 2026-06-04 Buy
ChemScene CS-7003 IRL-1620 99.69% 142569-99-1 500??g $130 2026-06-04 Buy
ChemScene CS-7003 IRL-1620 99.69% 142569-99-1 1mg $221 2026-06-04 Buy
Product number Packaging Price Buy
255523 500ug $466 Buy
PED-4285-V 0.5mg $549.71 Buy
FS108425 1mg $162.25 Buy
CS-7003 500??g $130 Buy
CS-7003 1mg $221 Buy

IRL-1620 Chemical Properties,Uses,Production

Biological Activity

IRL-1620 is a potent and selective endorphin receptor (endothelin receptor) type B agonist with a Ki of 16 pM.

in vitro

IRL-1620 is the most potent and specific ligand for the ETB receptor (K i ETA/ K i ETB=120,000) as judged by the K i values for ETA (19 μM) and ETB (16 PM) receptors. IRL-1620 is 60 times more selective for the ETB receptor than ET-3 (K i ETA /K i ETB=1,900).

target

IC50: 16 pM (Endothelin receptor B), 19 μM (Endothelin receptor A)

storage

-20°C (desiccate)

IRL-1620 Preparation Products And Raw materials

Raw materials

Preparation Products

IRL-1620 Suppliers

Global( 106)Suppliers
Supplier Tel Email Country ProdList Advantage
Combio (Suzhou) Ltd. 17751201929; 17751201929 jianyang_yu@combiosz.com China 2989 58
Zhejiang Jiekun Biotechnology Co., Ltd 0571-88211921 15397062932 sales1@gotopbio.com China 4864 58
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
NCE Biomedical Co.,Ltd. 4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 China 1490 55
MedChemexpress LLC 021-58955995 sales@medchemexpress.cn United States 4853 58
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632; sales@reading-chemicals.com China 15165 58
LETOPHARM LIMITED +86-21-5821 5861 sales@letopharm.com China 2374 58

View Lastest Price from IRL-1620 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sovateltide pictures 2026-08-25 Sovateltide
142569-99-1
$70.00-700.00 10kg 0.99 20tons Zibo Hangyu Biotechnology Development Co., Ltd
IRL-1620 pictures 2026-07-27 IRL-1620
142569-99-1
$957.00 10g TargetMol Chemicals Inc.
 IRL-1620 pictures 2020-02-14 IRL-1620
142569-99-1
$7.00 1KG 99% 100kg Career Henan Chemical Co
  • Sovateltide pictures
  • Sovateltide
    142569-99-1
  • $70.00-700.00
  • 0.99
  • Zibo Hangyu Biotechnology Development Co., Ltd
  • IRL-1620 pictures
  • IRL-1620
    142569-99-1
  • $957.00
  • TargetMol Chemicals Inc.
  •  IRL-1620 pictures
  • IRL-1620
    142569-99-1
  • $7.00
  • 99%
  • Career Henan Chemical Co
IRL-1620, HUMAN IRL-1620 ENDOTHELIN-1(8-21), N-SUC-[GLU9, ALA11,15] N-SUC-[GLU9, ALA11,15]ENDOTHELIN-I (8-21) N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN, 8-21 SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP-OH SUCCINYL-(GLU9,ALA11,15)-ENDOTHELIN-1 (8-21) SUC-[GLU9, ALA11,15]-ENDOTHELIN-1 (8-21) SUC-[GLU9, ALA11, 15] ENDOTHELIN-1 (8-21), HUMAN IRL-1620(ENDOTHELIN-1(8-21), N-SUC-(GLU9 ,ALA11,15) SYNTHETIC >97% n-succinyl-[glu9, ala11,15]-endothelin 1 fragment 8-21 IRL-1620, N-Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp, N-Succinyl-[Glu9, Ala11,15]-Endothelin1 fragment 8-21 M.W. 1820.97 C86H117N17O27 IRL-1620;N-SUCCINYL-[GLU9, ALA11,15]-ENDOTHELIN 1 FRAGMENT 8-21 SUC-ASP-GLU-GLU-ALA-VAL-TYR-PHE-ALA-HIS-LEU-ASP-ILE-ILE-TRP: SUC-DEEAVYFAHLDIIW Endothelin-1 (8-21), succinyl-(Glu(9),Ala(11,15))- L-Tryptophan, N-(3-carboxy-1-oxopropyl)-L-alanyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-tyrosyl-L-alanyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl- Succinyl-(glutamyl(9)-alanyl(11,15))-endothelin-1 (8-21) SPI-1620 28: PN: WO2007112069 SEQID N-(3-Carboxy-1-oxopropyl)-L-alpha-aspartyl-L-alpha-glutamyl-L-alpha-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-alpha-aspartyl-L-isoleucyl-L-isoleucyl-L-tryptophan N-Suc-Asp-Glu-Glu-Ala-Val-Tyr-Phe-Ala-His-Leu-Asp-Ile-Ile-Trp Succinyl-(Glu9,Ala1115)-Endothelin-1 (8-21), IRL-1620 L-Tryptophan, N-(3-carboxy-1-oxopropyl)-L-α-aspartyl-L-α-glutamyl-L-α-glutamyl-L-alanyl-L-valyl-L-tyrosyl-L-phenylalanyl-L-alanyl-L-histidyl-L-leucyl-L-α-aspartyl-L-isoleucyl-L-isoleucyl- Succinyl-[Glu9,Ala11,15]-Endothelin-1 (8-21) / Sovateltide Succinyl-(Glu?,Ala??·??)-Endothelin-1 (8-21) Sovateltide 142569-99-1 C86H117N17O27 Endothelins Peptides Agonist Amino Acids and Peptides BioChemical Biochemicals and Reagents Endothelin receptor