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4-Bromo-6-methoxyindole

4-Bromo-6-methoxyindole Structure
4-Bromo-6-methoxyindole structure
CAS No.
393553-55-4
Chemical Name:
4-Bromo-6-methoxyindole
Synonyms
4-Bromo-6-methoxyindole;4-BROMO-6-METHYLOXY INDOLE;4-bromo-6-methoxy-1H-indole;4-broMo-6-Methyloxyl indole;1H-Indole, 4-broMo-6-Methoxy-
CBNumber:
CB1348446
Molecular Formula:
C9H8BrNO
Molecular Weight:
226.07
MDL Number:
MFCD03095207
MOL File:
393553-55-4.mol
MSDS File:
SDS
Last updated:2026-09-12 18:49:12
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4-Bromo-6-methoxyindole Properties

Boiling point 346.8±22.0 °C(Predicted)
Density 1.591±0.06 g/cm3(Predicted)
storage temp. Keep in dark place,Inert atmosphere,Room temperature
pka 16.29±0.30(Predicted)
Appearance Off-white to light brown Solid
InChI InChI=1S/C9H8BrNO/c1-12-6-4-8(10)7-2-3-11-9(7)5-6/h2-5,11H,1H3
InChIKey CZJYKEPYJHPVOD-UHFFFAOYSA-N
SMILES N1C2=C(C(Br)=CC(OC)=C2)C=C1

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

4-Bromo-6-methoxyindole price More Price(36)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Matrix Scientific 203521 4-Bromo-6-methoxy-1H-indole 393553-55-4 1.00g $104 2026-05-18 Buy
Matrix Scientific 203521 4-Bromo-6-methoxy-1H-indole 393553-55-4 5.00g $408 2026-05-18 Buy
Matrix Scientific 203521 4-Bromo-6-methoxy-1H-indole 393553-55-4 10.00g $645 2026-05-18 Buy
Synthonix B23459 4-Bromo-6-methoxy-1H-indole 97% 393553-55-4 100mg $40 2026-05-06 Buy
Synthonix B23459 4-Bromo-6-methoxy-1H-indole 97% 393553-55-4 250mg $60 2026-05-06 Buy
Product number Packaging Price Buy
203521 1.00g $104 Buy
203521 5.00g $408 Buy
203521 10.00g $645 Buy
B23459 100mg $40 Buy
B23459 250mg $60 Buy

4-Bromo-6-methoxyindole Chemical Properties, Uses, Production

Synthesis

Acetamide, N-(3-bromo-5-methoxyphenyl)-N-hydroxy-

1431711-54-4

4-BROMO-6-METHOXYINDOLE

393553-55-4

General procedure for the synthesis of 4-bromo-6-methoxy-1H-indole from the compound (CAS: 1431711-54-4): (b) N-(3-bromo-5-methoxyphenyl)-N-hydroxyacetamide (360 mg, 1.384 mmol) was dissolved in vinyl acetate (1.92 mL) followed by addition of Li2PdCl4 (18.2 mg, 69 μmol). The reaction mixture was stirred at 60°C for 3 hours. After completion of the reaction, the reaction mixture was diluted with ethyl acetate (EtOAc) and brine, the organic layer was separated and concentrated under reduced pressure to give a solid. The solid was dissolved in methanol (20 mL), 1N NaOH aqueous solution (2.61 mL, 2.61 mmol) was added and stirred for 2 hours at room temperature. The reaction mixture was quenched with 2N HCl aqueous solution (1.3 mL, 2.6 mmol) followed by addition of sodium carbonate (500 mg). After addition of ethyl acetate (50 mL), the organic layer was separated, dried over anhydrous sodium sulfate (Na2SO4), filtered and concentrated. The residue was purified by column chromatography (20 g silica gel, ethyl acetate/heptane, gradient from 0/100 to 1/4) to afford the title compound as a liquid (145 mg, 46% yield, two steps).1H-NMR (600 MHz; DMSO-d6): δ 11.26 (brs, 1H), 7.31 (dd, 1H), 6.93 (d, 1H), and 6.90 (d, 1H), 6.29 (dd, 1H), 3.78 (s, 3H).

References

[1] Patent: WO2013/61305, 2013, A1. Location in patent: Page/Page column 45; 46

4-Bromo-6-methoxyindole Preparation Products And Raw materials

Raw materials

Acetamide, N-(3-bromo-5-methoxyphenyl)-N-hydroxy- Water Methanol Sodium hydroxide

Preparation Products

4-Bromo-6-methoxyindole Suppliers

Global Suppliers ( 91)
Supplier Tel Email Country ProdList Advantage
Beijing YiboYuntian Technology Co., Ltd. 13811826434 lichen13811826434@126.com China 702 58
Shenzhen Gre-syn Chemical Technology Co., Ltd. 13226079980 761330897@qq.com China 1162 55
Wuhan TCASChem Technology Co., Ltd. 027-86697669 13986148687 sales@tcaschem.com China 3997 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 13167063860 anhua.mao@aladdin-e.com China 29977 65
Shanghai Devinchem Ltd 027-65318838 13646286950 sales@devinchem.com China 2983 58
Shanghai Run-Biotech Co., Ltd. 021-57171705 13817537615 sales@run-biotech.com China 2277 58
CEG Chemical Science&Technology Co., Ltd. Mobile:13665161512 China 1784 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Shanghai Synteam Biochem CO.,ltd +86-021-58380978 13482386415 info@systeambc.com China 897 50
Shanghai Jovan Biochemical Technology Co. Ltd. +86-021-61654350 1245958370@qq.com China 2979 50
Supplier Advantage
Beijing YiboYuntian Technology Co., Ltd. 58
Shenzhen Gre-syn Chemical Technology Co., Ltd. 55
Wuhan TCASChem Technology Co., Ltd. 55
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Shanghai Devinchem Ltd 58
Shanghai Run-Biotech Co., Ltd. 58
CEG Chemical Science&Technology Co., Ltd. 58
Bide Pharmatech Ltd. 60
Shanghai Synteam Biochem CO.,ltd 50
Shanghai Jovan Biochemical Technology Co. Ltd. 50

View Latest Price from 4-Bromo-6-methoxyindole manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-BROMO-6-METHOXYINDOLE pictures 2020-01-13 4-BROMO-6-METHOXYINDOLE
393553-55-4
 $9.80 1g ≥99% 100kg Career Henan Chemical Co

4-Bromo-6-methoxyindole Spectrum

4-BROMO-6-METHOXYINDOLE(393553-55-4)1HNMR

393553-55-4 (4-Bromo-6-methoxyindole) Related Search:

4-Bromo-6,7-dimethoxy-1H-indole-2-carboxylic acid Bromoharmine HBr 4-Bromo-7-ethoxy-6-methoxy-1H-indole-2-carboxylic acid 4-Bromo-6-ethoxy-7-methoxy-1H-indole-2-carboxylic acid 5-Bromo-8H-1,3-dioxa-8-aza-as-indacene-7-carboxylic acid methyl ester
4-Bromo-7-ethoxy-6-methoxy-1H-indole-2-carboxylic acid methyl ester 7-Bromo-4-methoxyindole 4-Bromo-6-methoxyindole 4-Bromo-6,7-dimethoxy-1H-indole-2-carboxylic acid methyl ester Bromoharmaline, HBr
6-Bromo-4-methoxyindole 3-Bromo-5-methoxy-1H-indole 3-Bromo-5-methoxyindole-1-carboxylic acid tert-butyl ester 5-Bromo-8H-1,3-dioxa-8-aza-as-indacene-7-carboxylic acid

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4-BROMO-6-METHYLOXY INDOLE 4-bromo-6-methoxy-1H-indole 1H-Indole, 4-broMo-6-Methoxy- 4-broMo-6-Methyloxyl indole 4-Bromo-6-methoxyindole 393553-55-4