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(R)-N-Boc-3-Amino-3-phenylpropanoic acid

CAS No.
161024-80-2
Chemical Name:
(R)-N-Boc-3-Amino-3-phenylpropanoic acid
Synonyms
Boc-β-Phe-OH;(R)-3-((tert-Butoxycarbonyl)aMino)-3-phenylpropanoic acid;BOC-BETA-PHE-OH;Boc-R-PHA;Boc-b-Phe-OH;Boc-R-(γ)-Phe;(R)-Boc-β-Phe-OH;BOC-PHG-(C*CH2)OH;DL-N-Boc-β-Phe-OH;(R)-Boc-beta-Phe-OH
CBNumber:
CB1368088
Molecular Formula:
C14H19NO4
Molecular Weight:
265.31
MDL Number:
MFCD01320859
MOL File:
161024-80-2.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-27 23:34:49

(R)-N-Boc-3-Amino-3-phenylpropanoic acid Properties

Melting point 123.4 °C
Boiling point 408.52°C (rough estimate)
Density 1.1356 (rough estimate)
refractive index 1.5110 (estimate)
storage temp. Sealed in dry,Room Temperature
pka 4.32±0.10(Predicted)
form Powder
color White
BRN 5404389
InChI InChI=1/C14H19NO4/c1-14(2,3)19-13(18)15-11(9-12(16)17)10-7-5-4-6-8-10/h4-8,11H,9H2,1-3H3,(H,15,18)(H,16,17)/t11-/s3
InChIKey JTNQFJPZRTURSI-LBPXTSNRNA-N
SMILES [C@H](C1C=CC=CC=1)(CC(=O)O)NC(=O)OC(C)(C)C |&1:0,r|
CAS DataBase Reference 161024-80-2(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P362+P364-P403+P233-P501c
Safety Statements  24/25
WGK Germany  3
HazardClass  IRRITANT
HS Code  29242990
NFPA 704
0
0 0

(R)-N-Boc-3-Amino-3-phenylpropanoic acid price More Price(76)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 09794 Boc-β-Phe-OH ≥96.0% (HPLC) 161024-80-2 1g $762 2023-06-20 Buy
Usbiological 265317 Boc-L-beta-phenylalanine Asreported 161024-80-2 500mg $347 2026-06-03 Buy
Usbiological 265317 Boc-L-beta-phenylalanine Asreported 161024-80-2 1g $595 2026-06-03 Buy
Usbiological 265317 Boc-L-beta-phenylalanine Asreported 161024-80-2 2g $832 2026-06-03 Buy
Usbiological 265317 Boc-L-beta-phenylalanine Asreported 161024-80-2 5g $1507 2026-06-03 Buy
Product number Packaging Price Buy
09794 1g $762 Buy
265317 500mg $347 Buy
265317 1g $595 Buy
265317 2g $832 Buy
265317 5g $1507 Buy

(R)-N-Boc-3-Amino-3-phenylpropanoic acid Chemical Properties,Uses,Production

Uses

(R)-Boc-beta-phenylalanine is an amino acid derivative that can be used as an organic intermediate.

Chemical Properties

white powder

Synthesis

(R)-3-Amino-3-phenylpropionic acid (2.1 g, 12.7 mmol, 1.0 equiv.) and NaHCO3 (1.6 g, 19 ) were dissolved in water (30 mL). mmol, 1.5 equiv.) were dissolved in water (30 mL). Dioxane (30 mL) and [(CH3)3CO2C]2O (4.1 g, ) were dissolved in water (30 mL). 19 mmol, 1.5 equiv.) were added to the reaction mixture. The solution was stirred at room temperature for 8 hours. The solution was analyzed by TLC (SiO2, 50/25/25 The complete conversion of (R)-3-amino-3-phenylpropionic acid was confirmed by TLC (SiO2, 50/25/25 n-BuOH/HOAc/H2O). The solvent was removed by rotary evaporation. Distribute the crude mixture between HCl (1%) and EtOAc . the crude mixture was partitioned between HCl (1%) and EtOAc . The aqueous layer was extracted with EtOAc. The combined organic extracts were dried with Na2SO4. The solvent was filtered and concentrated. The crude was purified by column chromatography, eluting with 10% , CH3OH/DCM, and then with 10% . CH3OH/DCM to give (R)-Boc-beta-phenylalanine.

(R)-N-Boc-3-Amino-3-phenylpropanoic acid Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 150)Suppliers
Supplier Tel Email Country ProdList Advantage
Kanghua (Shanghai) New Drug Development Co., Ltd. 021-61263370 18516560301 xingli@glbiochem.com China 5637 58
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
Meryer (Shanghai) Chemical Technology Co., Ltd. 4006356688 18621169109 market03@meryer.com China 40202 62
Shanghai HC Biotech Co., Ltd 021-20227858 sale@hcbiotech.com.cn China 1173 55
Alfa Aesar 400-6106006 saleschina@alfa-asia.com China 30103 84
Wuhan Chemwish Technology Co., Ltd 86-027-67849912 sales@chemwish.com China 35884 56
Capot Chemical Co., Ltd +86 (0) 571 85 58 67 18 China 18187 66
Suzhou haiyu Biochem Industrial Co., LTD 512-68097639 18013585858 744942877@qq.com China 915 62
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Adamas Reagent, Ltd. 400-6009262 15618770481 yhx@titansci.com China 14098 59

View Lastest Price from (R)-N-Boc-3-Amino-3-phenylpropanoic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
	(R)-N-Boc-3-Amino-3-phenylpropanoic acid pictures 2019-09-02 (R)-N-Boc-3-Amino-3-phenylpropanoic acid
161024-80-2
$7.00 1KG 99% Career Henan Chemical Co

(R)-N-Boc-3-Amino-3-phenylpropanoic acid Spectrum

BOC-PHG-(C*CH2)OH (R)-Boc-beta-Phe-OH (3R)-3-{[(tert-butoxy)carbonyl]amino}-3-phenylpropanoic acid Boc-R-PHA BOC PROTECTED (R)-B-PHENYLALANINE BOC-(R)-3-AMINO-3-PHENYLPROPANOIC ACID BOC-(R)-3-AMINO-3-PHENYLPROPIONIC ACID BOC-L-B-PHENYLALANINE BOC-L-BETA-PHENYLALANINE (R)-N-(TERT-BUTOXYCARBONYL)-3-AMINO-3-PHENYLPROPIONIC ACID (R)-N-BOC-BETA-PHENYL-BETA-ALANINE (R)-N-BOC-3-AMINO-3-PHENYLPROPANOIC ACID RARECHEM AK PT B077 N-T-BUTOXYCARBONYL-(R)-3-AMINO-3-PHENYLPROPIONIC ACID (R)-3-(BOC-AMINO)-3-PHENYLPROPIONIC ACID (R)-3-TERT-BUTOXYCARBONYLAMINO-3-PHENYL-PROPIONIC ACID Boc-beta-(R)-3-phenylalanine (R)-N-boc-3-Amino-3-phenylpropanoicacid(e.e.) (R)-N-tert-Butoxycarbonyl-3-amino-3-phenylpropanoic acid (R)-N-BOC-3-AMINO-3-PHENYLPROPANOIC ACID 95% (98% E.E.) Boc-b-Phe-OH (R)-3-(Boc-amino)-3-phenylpropionic acid, Boc-L-β-phenylalanine (R)-N-BOC-3-Amino-3-phenylpropanoic acid, 98% ee BOC-(R)--phenylalanine Boc-D-β-Phe-OH,(R)-3-(Boc-aMino)-3-phenylpropionic acid (3R)-3-aMino-4-(tert-butoxy)-4-oxo-3-phenylbutanoic acid (3r)-3-[(2-Methylpropan-2-yl)oxycarbonylaMino]-3-phenylpropanoic Acid Benzenepropanoic acid, β-[[(1,1-dimethylethoxy)carbonyl]amino]-, (βR)- Boc-L-?-phenylalanine98 % approx Boc-R-(γ)-Phe (Tert-Butoxy)Carbonyl (R)-3-Amino-3-phenylpropionic acid (R)-3-(BOC-AMINO)-3-PHENYLPROPANOIC ACID (R)-N-Boc-3-Amino-3-phenyL (R)-3-(Boc-amino)-3-phenylpropionicacid,95% (R)-N-BOC-3-Amino-3-phenylpropanoicaci (R)-N-Boc-3-Amino-3-phenylpropanoic acid USP/EP/BP Boc-L-β-phenylalanine DL-N-Boc-β-Phe-OH (βR)-β-[[(1,1-Dimethylethoxy)carbonyl]amino]benzenepropanoic acid (R)-Boc-β-Phe-OH (R)-3-((tert-Butoxycarbonyl)aMino)-3-phenylpropanoic acid BOC-BETA-PHE-OH Boc-β-Phe-OH 161024-80-2 Peptide Synthesis Specialty Synthesis Unnatural Amino Acid Derivatives Beta-Amino Acids Unusual Amino Acids - Phe 3-Amino-3-phenylpropionic Acid Analogs 3-Amino-3-phenylpropanoic Acid Analogs B-Amino API intermediates