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DL-Phenylalanine

CAS No.
150-30-1
Chemical Name:
DL-Phenylalanine
Synonyms
3-AMINO-3-PHENYLPROPANOIC ACID;DL-3-PHENYLALANINE;H-DL-PHE-OH;DL-PHENYALANINE;3 AMINO-PHENYLPROPIONIC ACID;D,L-PHE;DLPA 375;NSC 9959;FEMA 3726;DL-Phenylalani
CBNumber:
CB4140195
Molecular Formula:
C9H11NO2
Molecular Weight:
165.19
MDL Number:
MFCD00064225
MOL File:
150-30-1.mol
MSDS File:
SDS
Last updated:2026-01-13 11:20:46
Product description Number Pack Size Price
DL-Phenylalanine ReagentPlus , 99% 147966 25g $38.6
DL-Phenylalanine ReagentPlus , 99% 147966 100g $75.3
DL-Phenylalanine >98.0%(HPLC)(T) P0136 25g $30
DL-Phenylalanine >98.0%(HPLC)(T) P0136 250g $128
DL-Phenylalanine 99+% 237465 25g $156
More product size

DL-Phenylalanine Properties

Melting point 266-267 °C (dec.) (lit.)
Boiling point 293.03°C (rough estimate)
Density 1.1603 (rough estimate)
FEMA 3726 | D,L-PHENYLALANINE
refractive index 1.5200 (estimate)
storage temp. Store at RT.
solubility Water (Sparingly, Sonicated)
pka pK1 2.58; pK2 9.24(at 25℃)
form Powder
color White
Odor odorless
Odor Type odorless
biological source synthetic
Water Solubility 14.11 g/L (25 ºC)
Merck 14,7271
JECFA Number 1432
BRN 1910407
Stability Stable. Incompatible with strong oxidizing agents.
Major Application peptide synthesis
Cosmetics Ingredients Functions FRAGRANCE
SKIN CONDITIONING
HAIR CONDITIONING
InChI 1S/C9H11NO2/c10-8(9(11)12)6-7-4-2-1-3-5-7/h1-5,8H,6,10H2,(H,11,12)
InChIKey COLNVLDHVKWLRT-UHFFFAOYSA-N
SMILES NC(Cc1ccccc1)C(O)=O
LogP 0.24
CAS DataBase Reference 150-30-1(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) DL-PHENYLALANINE
FDA UNII 8P946UF12S
NIST Chemistry Reference L-Phenylalanine(150-30-1)
EPA Substance Registry System Phenylalanine (150-30-1)
UNSPSC Code 12352209
NACRES NA.22

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
PPE Eyeshields, Gloves, type N95 (US)
Hazard Codes  Xi,C
Risk Statements  36/37/38-34
Safety Statements  37/39-24/25-45-36/37/39-27-26
WGK Germany  3
Hazard Note  Irritant
TSCA  TSCA listed
HS Code  29224995
Storage Class 11 - Combustible Solids
NFPA 704
0
0 0

DL-Phenylalanine price More Price(31)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 147966 DL-Phenylalanine ReagentPlus , 99% 150-30-1 25g $38.6 2025-07-31 Buy
Sigma-Aldrich 147966 DL-Phenylalanine ReagentPlus , 99% 150-30-1 100g $75.3 2025-07-31 Buy
TCI Chemical P0136 DL-Phenylalanine >98.0%(HPLC)(T) 150-30-1 25g $30 2025-07-31 Buy
TCI Chemical P0136 DL-Phenylalanine >98.0%(HPLC)(T) 150-30-1 250g $128 2021-12-16 Buy
Usbiological 237465 DL-Phenylalanine 99+% 150-30-1 25g $156 2021-12-16 Buy
Product number Packaging Price Buy
147966 25g $38.6 Buy
147966 100g $75.3 Buy
P0136 25g $30 Buy
P0136 250g $128 Buy
237465 25g $156 Buy

DL-Phenylalanine Chemical Properties,Uses,Production

Description

As an essential amino acid, phenylalanine is necessary for the production of tyrosine in human body, which cannot be synthesized from more basic substances in humans and other animals, meaning that it is obtained only by ingestion of phenylalanine or phenylalanine- containing proteins, which is particularly rich in eggs, chicken, liver, beef, breast milk of mammals, and soybeans, etc. There are three forms of phenylalanine: L-phenylalanine, the natural form found in protein-rich foods, D-phenylalanine, the synthetic mirror image and DL-Phenylalanine (DLPA), the mixture of both forms made in the laboratory that can maximize benefits. DLPA is manufactured for medical, feed, and nutritional applications, which can be used to produce food and drink products. It is marketed as a nutritional supplement due to its reputed analgesic and antidepressant effects. Besides, it can be applied for depression, attention deficit-hyperactivity disorder (ADHD), Parkinson's disease, chronic pain, osteoarthritis, rheumatoid arthritis, alcohol withdrawal symptoms, and a skin disease called vitiligo.

References

https://en.wikipedia.org/wiki/Phenylalanine
http://www.livestrong.com/article/501701-what-are-the-benefits-of- dl-phenylalanine/
http://www.webmd.com/vitamins-supplements/ingredientmono-653- phenylalanine.aspx? activeingredientid=653&activeingredientname=phenylalanine

Chemical Properties

DL-Phenylalanine has a sweet taste. It is an essential amino acid that plays a key role in the biosynthesis of other amino acids and some neurotransmitters.

Chemical Properties

White crystalline powder

Occurrence

Phenylalanine is the most commonly found aromatic amino acid in proteins and enzymes with a molar ratio of 3.5% compared to the other amino acids, about double the amount of any other aromatic amino acid. Reported found in white bread, macaroni, egg noodles, corn flakes, corn grits, oatmeal, wheat bran, wheat flakes, shredded wheat, barley, brown rice, rye flour, whole grain wheat flour, buttermilk, blue cheese, cheddar cheese, cottage cheese, cream cheese, parmesan cheese, bacon, cured ham, frankfurters, pork sausage, canned red kidney beans, canned sweet corn, canned peas, canned lima beans, canned potatoes, canned asparagus, canned snap beans, canned beets, beef, lamb, fresh ham, veal round, beef liver, chicken, chicken liver, turkey and other natural sources.

Uses

DL-Phenylalanine may be used in the synthesis of ternary piroxicam (Pir; 4-hydroxy-2-methyl-N-(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide) complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II).

Uses

Component of the artificial sweetner aspartame, q.v.; nutrient.

Uses

DL-Phenylalanine is used torelieve cases of minor depressionand other mood issues as well as and physical discomforts and pain. It is also used in acupunctureanesthesia, alcohol withdrawal.

Preparation

By microbial bioengineered process.

Definition

ChEBI: An aromatic amino acid that is alanine in which one of the methyl hydrogens is substituted by a phenyl group.

General Description

Phenylalanine is an amino acid. It participates in the preparation of ternary piroxicam complexes of Fe(II), Fe(III), Co(II), Ni(II), Cu(II) and Zn(II). Characterization of these complexes by elemental analyses, molar conductance, IR, UV-Vis, magnetic moment, diffuse reflectance and X-ray powder diffraction methods has been conducted. Crystalline DL-phenylalanine was prepared by its reduction in silica gel by solubility method.

reaction suitability

reaction type: solution phase peptide synthesis

Side effects

When taken by mouth: L-phenylalanine is commonly consumed in foods. L-phenylalanine, D-phenylalanine, and DL-phenylalanine are possibly safe when used as medicine, short-term. Side effects might include anxiety, headache, and constipation. When applied to the skin: Phenylalanine cream is possibly safe when used in the short-term.

Purification Methods

dl-Phenylalanine crystallises from H2O or H2O/EtOH in large plates and is dried under vacuum over P2O5. S-Phenylalanine ethyl ester hydrochloride has m 156-158o and [ ] D -7.8o (c 2, H2O) after crystallisation from EtOH/Et2O [Billimoria & Cook J Chem Soc 2328 1949, Beilstein 14 IV 1556]. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2156-2175 1961, Beilstein 14 III 1229, 14 IV 1553.]

156-06-9
150-30-1
Synthesis of DL-Phenylalanine from 3-Phenylpyruvic acid
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View Lastest Price from DL-Phenylalanine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
DL-Phenylalanine pictures 2026-03-02 DL-Phenylalanine
150-30-1
US $0.00 / kg 0.001kg 99% 100000T Anhuyan (Hainan) Biotechnology Co., LTD
DL-Phenylalanine pictures 2026-03-02 DL-Phenylalanine
150-30-1
US $0.00-0.00 / Kg/Drum 1KG 98.5%-101.5%; FCC-V 20 TONS WUHAN FORTUNA CHEMICAL CO., LTD
DL-Phenylalanine pictures 2026-03-02 DL-Phenylalanine
150-30-1
US $99.00-66.00 / kg 0.001kg 99% 5000 HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
  • DL-Phenylalanine pictures
  • DL-Phenylalanine
    150-30-1
  • US $0.00 / kg
  • 99%
  • Anhuyan (Hainan) Biotechnology Co., LTD
  • DL-Phenylalanine pictures
  • DL-Phenylalanine
    150-30-1
  • US $0.00-0.00 / Kg/Drum
  • 98.5%-101.5%; FCC-V
  • WUHAN FORTUNA CHEMICAL CO., LTD
  • DL-Phenylalanine pictures
  • DL-Phenylalanine
    150-30-1
  • US $99.00-66.00 / kg
  • 99%
  • HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
PHENYLALANINE, DL- PHENYALANINE, DL- RARECHEM AK HC T302 H-DL-PHE-OH FEMA 3726 LABOTEST-BB LTBB000477 DL-ALPHA-AMINO-BETA-PHENYLPROPIONIC ACID D,L-PHE DL-PHENYALANINE DL-PHENYLALANINE DL-2-AMINO-3-PHENYLPROPANOIC ACID DL-2-AMINO-3-PHENYLPROPIONIC ACID DL-A-AMINOHYDROCINNAMIC ACID DL-3-PHENYLALANINE 3 AMINO-PHENYLPROPIONIC ACID 3-AMINO-3-PHENYLPROPANOIC ACID DLPA 375 DL-Phenylalanine,(±)-2-Amino-3-phenylpropionic acid (+/-)-2-AMINO-3-PHENYLPROPIONIC ACID 2-AMINO-3-PHENYLPROPIONIC ACID Alanine, phenyl-, DL- beta-Phenylalanine, dl- DL-beta-Phenyl-alpha-alanine DL-N-Phenylalanine D,L, Phenylalanine, dry DL-PHENYLALANINE 98.5+% FCC DL-PHENYLALANINE CELL CULTURE TESTED Dl-PhenylalanineForBiochemistry AspartaMe IMpurity C DL-Phenylalanine ReagentPlus(R), 99% DL-Phenylalani DL-Phenylalanine Vetec(TM) reagent grade, 98% DL-Phenylalanine≥ 99% (Assay) (±)-2-Amino-3-phenylpropionic acid DL-β-Phenylalanine DL-Phenylalanine, FTIR VLOOKUP(C2,[1]Export!$D:$H,5,0) (2R)-2-ammonio-3-phenylpropanoate DL-Phenylalanine, >98.0%(HPLC) (+/-)-2-Amino-3-phenylpropionicacid=H-DL-Phe-OH DL-α-Amino-β-phenylpropionic acid (n)-2-amino-3-phenylpropionic acid DL-PHENYLALANINE,FCC PHENYLALANINE, DL-(P) PHENYLALANINE, DL(RG) DL-PHENYLALANINE(DL-ALPHA-AMINO-BETA-PHENYLPROPIONICACID) DL-beta-Phenylalanine (+-)-3-Phenyl-2-aminopropanoic acid Alanine, phenyl-, DL- (8CI) DL-a-Amino-b-phenylpropionic acid DL-b-Phenyl-a-alanine DL-b-Phenylalanine NSC 9959 Phenylalanine (9CI) DL-Phenylalanin (R,S)-2-Amino-3-phenyl-propionic acid rac-(2R*)-3-Phenyl-2-aminopropionic acid rac-(R*)-2-Amino-3-phenylpropionic acid DL-Phenylalanine,99%