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4-(4-N-BUTYLPHENYL)BENZOIC ACID

4-(4-N-BUTYLPHENYL)BENZOIC ACID structure

CAS No.: 59662-46-3

Chemical Name:: 4-(4-N-BUTYLPHENYL)BENZOIC ACID

Synonyms: RARECHEM AL BO 0889;4-Butylbibenzoic acid;4-Butyl-4''-carboxybiphenyl;4-(4-butylphenyl)benzoic acid;4-(4-N-BUTYLPHENYL)BENZOIC ACID;-butylbiphenyl-4-carboxylic acid;4'-Butylbiphenyl-4-carboxylic acid;4-BUTYL-4'-BIPHENYLCARBOXYLIC ACID;4'-Butylbiphenyl-4-carboxylic acid;4-N-BUTYLBIPHENYL-4'-CARBOXYLIC ACID

CBNumber:: CB1446643

Molecular Formula:: C17H18O2

Molecular Weight:: 254.32

MDL Number:: MFCD00222812

MOL File:: 59662-46-3.mol

MSDS File:: SDS

Last updated:2025-07-24 18:13:53

Product description	Number	Pack Size	Price
4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	B58964	250mg	$81
4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	B58964	1g	$87
4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	B58964	5g	$159
4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	B58964	10g	$210
4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	B58964	25g	$230
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4-(4-N-BUTYLPHENYL)BENZOIC ACID Properties

Boiling point	413.5±34.0 °C(Predicted)
Density	1.091±0.06 g/cm3 (20 ºC 760 Torr)
storage temp.	Sealed in dry,Room Temperature
pka	4.22±0.10(Predicted)
Appearance	White to off-white Solid
CAS DataBase Reference	59662-46-3(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338
Risk Statements	36/37/38
Safety Statements	26-36/37/39

4-(4-N-BUTYLPHENYL)BENZOIC ACID price More Price(14)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Synthonix	B58964	4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	59662-46-3	250mg	$81	2026-05-06	Buy
Synthonix	B58964	4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	59662-46-3	1g	$87	2026-05-06	Buy
Synthonix	B58964	4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	59662-46-3	5g	$159	2026-05-06	Buy
Synthonix	B58964	4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	59662-46-3	10g	$210	2026-05-06	Buy
Synthonix	B58964	4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 98%	59662-46-3	25g	$230	2026-05-06	Buy

Product number	Packaging	Price	Buy
B58964	250mg	$81	Buy
B58964	1g	$87	Buy
B58964	5g	$159	Buy
B58964	10g	$210	Buy
B58964	25g	$230	Buy

4-(4-N-BUTYLPHENYL)BENZOIC ACID Chemical Properties,Uses,Production

Uses

4''-Butylbiphenyl-4-carboxylic Acid is an intermediate used in the preparation of biphenylcarboxylates used as RARβ2 receptor agonist.

Synthesis

[1,1'-Biphenyl]-4-carboxylic acid, 4'-butyl-, methyl ester

1451206-56-6

59662-46-3

General Method 13: Synthesis of biaryl or aryl-heteroaryl carboxylic acids from 1-bromo-4-butylbenzene and arylboronic or heteroarylboronic acids by Suzuki coupling reaction. This method is specifically applied to the synthesis of 4-n-butylbiphenyl-4'-carboxylic acids. A mixture of methyl 4-(4-butylphenyl)benzoate (89.0 g, 0.332 mol) and NaOH (26.6 g, 0.664 mol) in THF/H2O (500 mL/100 mL) mixed solvent was heated to reflux and reacted overnight. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the completion of the reaction, THF was removed by distillation under reduced pressure.The residue was acidified to pH 3-4 with 2N HCl solution.The resulting mixture was filtered and the filter cake was washed with deionized water and dried to give 4-(4-butylphenyl)benzoic acid (60.0 g, yield: 71.1%) as white solid. The mass spectrum (ESI) showed m/z 255.0 ([M+H]+).

References

[1] Patent: WO2013/123456, 2013, A1. Location in patent: Paragraph 00269; 00271
[2] Patent: WO2017/84629, 2017, A1. Location in patent: Paragraph 00341
[3] Patent: WO2017/84630, 2017, A1. Location in patent: Paragraph 00444
[4] Patent: US2013/217619, 2013, A1. Location in patent: Page/Page column

4-(4-N-BUTYLPHENYL)BENZOIC ACID synthesis

Synthesis of 4-(4-N-BUTYLPHENYL)BENZOIC ACID from Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-

4-(4-N-BUTYLPHENYL)BENZOIC ACID Preparation Products And Raw materials

Raw materials

1-Bromo-4-butylbenzene 4'-Butyl-4-biphenylcarbonitrile 4-(METHOXYCARBONYL)PHENYLBORONIC ACID [1,1'-Biphenyl]-4-carboxylic acid, 4'-butyl-, methyl ester Tetrahydrofuran

Sodium hydroxide Water

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Preparation Products

4-(4-N-BUTYLPHENYL)BENZOIC ACID Suppliers

Global( 79)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	20124	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-2158073036	info@dakenam.com	China	13902	58
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29816	58
Nanjing Dolon Biotechnology Co.,Ltd.	18905173768	52513593@qq.com	CHINA	2972	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
SIMAGCHEM CORP	+86-5922680277 +86-13806087780	sale@simagchem.com	China	17346	58
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418671 +8618949823763	sales@tnjchem.com	China	34563	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	18895	58
Dayang Chem (Hangzhou) Co.,Ltd.	+86-0571-88938639 +8617705817739	info@dycnchem.com	China	52705	58
Nextpeptide Inc	+86-0571-81612335 +8613336028439	sales@nextpeptide.com	China	19908	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
career henan chemical co	58
Nanjing Dolon Biotechnology Co.,Ltd.	58
Alchem Pharmtech,Inc.	58
SIMAGCHEM CORP	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Nextpeptide Inc	58

View Lastest Price from 4-(4-N-BUTYLPHENYL)BENZOIC ACID manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2025-09-25	4-(4-n-butylphenyl)benzoic acid 59662-46-3	US $200.00-1.00 / KG	1KG	99%, 99.5% Sublimated	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-04-06	4-(4-N-BUTYLPHENYL)BENZOIC ACID 59662-46-3	US $0.00-0.00 / kg	1kg	98.0%	1000kg	LY Global chemicals co.,ltd .
2019-08-27	4-(4-N-BUTYLPHENYL)BENZOIC ACID 59662-46-3	US $3.00 / KG	3KG	98%	1kg,5kg,100kg	Career Henan Chemical Co

4-(4-n-butylphenyl)benzoic acid
59662-46-3
US $200.00-1.00 / KG
99%, 99.5% Sublimated
Henan Fengda Chemical Co., Ltd

4-(4-N-BUTYLPHENYL)BENZOIC ACID
59662-46-3
US $0.00-0.00 / kg
98.0%
LY Global chemicals co.,ltd .

4-(4-N-BUTYLPHENYL)BENZOIC ACID
59662-46-3
US $3.00 / KG
98%
Career Henan Chemical Co

4-(4-N-BUTYLPHENYL)BENZOIC ACID Spectrum

4-(4-N-BUTYLPHENYL)BENZOIC ACID(59662-46-3)¹HNMR

59662-46-3(4-(4-N-BUTYLPHENYL)BENZOIC ACID)Related Search:

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3-(4-N-BUTYLPHENYL)BENZOIC ACID 97% 4-(4-TERT-BUTYLPHENYL)BENZOIC ACID,4-(4-TERT-BUTYLPHENYL)BENZOIC ACID 99+% 4'-N-OCTYLBIPHENYL-4-CARBOXYLIC ACID RARECHEM AN KB 0948 RARECHEM AN KB 1350

4-(4'-N-HEPTYLPHENYL)BENZOIC ACID 4'-(2-METHYLBUTYL)[1,1'-BIPHENYL]-4-CARBOXYLIC ACID 4-(4-N-BUTYLPHENYL)BENZOIC ACID RARECHEM AL BO 2395 4-(4-n-Pentylphenyl)benzoic acid

4-N-HEXYLBIPHENYL-4'-CARBOXYLIC ACID

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RARECHEM AL BO 0889 4-BUTYL-4'-BIPHENYLCARBOXYLIC ACID 4-N-BUTYLBIPHENYL-4'-CARBOXYLIC ACID 4-(4-N-BUTYLPHENYL)BENZOIC ACID 4-Butyl-4''-carboxybiphenyl [1,1'-Biphenyl]-4-carboxylicacid, 4'-butyl- 4-(4-N-BUTYLPHENYL)BENZOIC ACID ISO 9001：2015 REACH 4-(4-butylphenyl)benzoic acid 4'-Butylbiphenyl-4-carboxylic acid 4'-Butyl-[1,1'-biphenyl]-4-carboxylic acid 4-Butylbibenzoic acid 4'-Butylbiphenyl-4-carboxylic acid -butylbiphenyl-4-carboxylic acid 59662-46-3 Biphenyl & Diphenyl ether