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2,4-Diethylpyridine dicarboxylate

2,4-Diethylpyridine dicarboxylate structure

CAS No.: 41438-38-4

Chemical Name:: 2,4-Diethylpyridine dicarboxylate

Synonyms: diethyl pyridine-2,4-dicarboxylate;2,4-pyridine dicarboxylate;2,4-DPD;Ai3-17897;Diethyl-2,4-pdc;2,4-Pdc diethyl ester;2,4-Pyridinedicarboxylic;DIETHYL 2,4-PYRIDINECARBOXYLATE;Diethyl 2,4-pyridinedicarboxylate;2,4-Diethylpyridine dicarboxylate

CBNumber:: CB1454066

Molecular Formula:: C11H13NO4

Molecular Weight:: 223.23

MDL Number:: MFCD00152168

MOL File:: 41438-38-4.mol

MSDS File:: SDS

TDS File:: TDS

Last updated:2026-09-12 18:49:14

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2,4-Diethylpyridine dicarboxylate Properties

Melting point	31 °C
Boiling point	330.9±22.0 °C(Predicted)
Density	1.165±0.06 g/cm3(Predicted)
vapor pressure	0.022Pa at 25℃
storage temp.	2-8°C
solubility	≤50mg/ml in ethanol;20mg/ml in DMSO;30mg/ml in dimethyl formamide
pka	-0.69±0.10(Predicted)
form	Crystalline
color	White to Almost white
Cosmetics Ingredients Functions	SKIN CONDITIONING HAIR CONDITIONING
InChI	InChI=1S/C11H13NO4/c1-3-15-10(13)8-5-6-12-9(7-8)11(14)16-4-2/h5-7H,3-4H2,1-2H3
InChIKey	MUUDQLHCIAOWPR-UHFFFAOYSA-N
SMILES	C1(C(OCC)=O)=NC=CC(C(OCC)=O)=C1
LogP	1.92 at 20℃ and pH7.82
Surface tension	56.3mN/m at 1g/L and 19.7℃
CAS DataBase Reference	41438-38-4
FDA UNII	4SN4572M5S

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313

HS Code

2933.39.9200

REACH Registrations

Active

NFPA 704

	3
2		0

2,4-Diethylpyridine dicarboxylate price More Price(38)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TCI Chemical	D5518	Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC)	41438-38-4	200mg	$45	2026-04-30	Buy
TCI Chemical	D5518	Diethyl 2,4-Pyridinedicarboxylate >97.0%(GC)	41438-38-4	1g	$135	2026-04-30	Buy
Cayman Chemical	71200	2,4-DPD ≥98%	41438-38-4	10mg	$21	2026-04-30	Buy
Cayman Chemical	71200	2,4-DPD ≥98%	41438-38-4	25mg	$46	2026-04-30	Buy
Cayman Chemical	71200	2,4-DPD ≥98%	41438-38-4	50mg	$86	2026-04-30	Buy

Product number	Packaging	Price	Buy
D5518	200mg	$45	Buy
D5518	1g	$135	Buy
71200	10mg	$21	Buy
71200	25mg	$46	Buy
71200	50mg	$86	Buy

2,4-Diethylpyridine dicarboxylate Chemical Properties, Uses, Production

Uses

Diethyl pyridine-2,4-dicarb is a potent prolyl 4-hydroxylase-directed proinhibitor. Diethyl pyridine-2,4-dicarb inhibits prolyl hydroxylation and procollagen processing in chick-embryo calvaria[1].

Biological Activity

2,4-dpd is a cell permeable, competitive inhibitor of the oxygen-sensing enzyme hif-α prolyl hydroxylase (hif-ph) [1].hypoxia-inducible factor (hif) is a transcription factor with a key role in cellular responses to hypoxia in a variety of organisms. the hif system plays an important role in angiogenesis, erythropoiesis, energy utilization, glucose/energy metabolism, tumour development, and ischaemic/hypoxic disease. genetic or pharmacological inactivation of the hif hydroxylases results in a constitutive activation of the hif pathway with little or even absent regulation by oxygen remaining. the oxygen-sensing enzyme hif-α prolyl hydroxylase catalyzes hydroxylation of specific prolyl and asparaginyl residues in the regulatory hif-α subunits [2].exposure to 2,4-dpd limited prolyl 4-hydroxylase activity in c. elegans., where their esters are hydrolyzed to form competitors of a -ketoglutarate. 2,4-dpd showed dramatic effects among the progeny. when exposed to a high level of 2,4-dpd (2.7 mm), all progeny died regardless of genotype of c. elegans. the dead embryos arrested at the twofold stage [1].

References

[1] friedman l, higgin j j, moulder g, et al. prolyl 4-hydroxylase is required for viability and morphogenesis in caenorhabditis elegans[j]. proceedings of the national academy of sciences, 2000, 97(9): 4736-4741.
[2] schofield c j, ratcliffe p j. signalling hypoxia by hif hydroxylases[j]. biochemical and biophysical research communications, 2005, 338(1): 617-626.

2,4-Diethylpyridine dicarboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

2,4-Pyridinedimethanol

2,4-Diethylpyridine dicarboxylate Suppliers

Global Suppliers ( 115)

Supplier	Tel	Email	Country	ProdList	Advantage
Shanghai T&W Pharmaceutical Co., Ltd.	+86 21 61551611		China	9874	58
Shanghai Jian Chao Chemical Technology Co., Ltd.	150-2103-5486 18017383231	983544897@qq.com	China	9335	55
TOKYO CHEMICAL INDUSTRY CO., LTD.	03-36680489	Sales-JP@TCIchemicals.com	Japan	28364	80
TCI Europe	320-37350700	sales@tcieurope.eu	Europe	23654	75
TCI AMERICA	800-4238616	sales@tciamerica.com	Americas	23636	75
Shanghai Yolne Chemical Co., Ltd.	021-62960152	934678158@qq.com	China	9886	55
Shanghai Hao Yun Chemical Science Co.,Ltd.	021-68367562	sales@haoyunchem.com	China	493	55
Nanjing ShengSai Chemical Co., Ltd.	025-85205967 13951876367	shengsaichem@163.com	China	818	58
Finetech Industry Limited	027-87465837 19945049750	sales@finetechnology-ind.com	China	9331	58
Shenzhen Nexconn Pharmatechs Ltd.	0755-89396905	admin@nexconn.com	China	299	55

Supplier	Advantage
Shanghai T&W Pharmaceutical Co., Ltd.	58
Shanghai Jian Chao Chemical Technology Co., Ltd.	55
TOKYO CHEMICAL INDUSTRY CO., LTD.	80
TCI Europe	75
TCI AMERICA	75
Shanghai Yolne Chemical Co., Ltd.	55
Shanghai Hao Yun Chemical Science Co.,Ltd.	55
Nanjing ShengSai Chemical Co., Ltd.	58
Finetech Industry Limited	58
Shenzhen Nexconn Pharmatechs Ltd.	55

View Latest Price from 2,4-Diethylpyridine dicarboxylate manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2026-09-18	Diethyl 2,4-Pyridinedicarboxylate 41438-38-4		1g	98.0%	1kg/month	WUHAN FORTUNA CHEMICAL CO., LTD
2026-09-18	Diethyl pyridine-2,4-dicarboxylate 41438-38-4	$1.00-10.00		98%+	1 ton	Shenzhen Nexconn Pharmatechs Ltd
2026-06-08	2,4-DPD 41438-38-4	$29.00		99.74%	10g	TargetMol Chemicals Inc.

Diethyl 2,4-Pyridinedicarboxylate
41438-38-4
98.0%
WUHAN FORTUNA CHEMICAL CO., LTD

Diethyl pyridine-2,4-dicarboxylate
41438-38-4
$1.00-10.00
98%+
Shenzhen Nexconn Pharmatechs Ltd

2,4-DPD
41438-38-4
$29.00
99.74%
TargetMol Chemicals Inc.

2,4-Diethylpyridine dicarboxylate Spectrum

2,4-DIETHYLPYRIDINE DICARBOXYLATE(41438-38-4)¹HNMR

41438-38-4 (2,4-Diethylpyridine dicarboxylate) Related Search:

2,4-Pyridinedicarboxylic acid Ethyl isonicotinate Ethyl picolinate 2,4-Diethylpyridine dicarboxylate 2-FORMYL-4-PICOLINE

4-Methyl-pyridine-2-carboxylic acid 2-(Ethoxycarbonyl)isonicotinic acid 4-(Ethoxycarbonyl)pyridine-2-carboxylic acid 4-Methyl-pyridine-2-carboxylic acid ethyl ester 2 -Methylisonicotinic acid ethyl ester

2,4-Pyridinecarboxylic acid, 4-methyl ester 2-Pyridinecarboxylicacid,4-(hydroxymethyl)-,methylester(9CI) 2-methyl-4-pyridinecarboxylic acid methyl ester CHEMPACIFIC 38149 2-Pyridinecarboxylicacid,4-methyl-,methylester(9CI)

Dimethyl 2,4-pyridinedicarboxylate

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DIETHYL 2,4-PYRIDINECARBOXYLATE Diethyl 2,4-pyridinedicarboxylate 2,4-Pyridinedicarboxylic acid, diethyl ester Pyridine-2,4-Dicarboxylic Acid Diethyl Ester 2,4-PYRIDINEDICARBOXYLIC ACID DIETHYL ESTER 2,4-DPD 2,4-Pyridinedicarboxylic 2,4-pyridinedicarboxylicacid,ethylester diethyl 2,4-pyridinedicarboxylic acid 2,4-Pdc diethyl ester Ai3-17897 Diethyl-2,4-pdc 2,4-pyridine dicarboxylic acid 2,4-diethyl ester 2,4-DIETHYL PYRIDINE-2,4-DICARBOXYLATE pyridine-2,4-dicarboxylic acid diethyl ester Collagen formation,Diethyl ester,Chick-embryo calvaria,2,4DPD,inhibit,Inhibitor,Prolyl hydroxylation,2,4 DPD,Procollagen 2,4-pyridine dicarboxylate diethyl pyridine-2,4-dicarboxylate 2,4-Diethylpyridine dicarboxylate 41438-38-4 Pyridines, Pyrimidines, Purines and Pteredines