(S)-PBMC (PBMC)
- CAS No.
- 1352138-54-5
- Chemical Name:
- (S)-PBMC (PBMC)
- Synonyms
- (S)-PBMC (PBMC);N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-carbamic acid (1S)-1-phenylethyl ester;Carbamic acid, N-(2-aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-, (1S)-1-phenylethyl ester
- CBNumber:
- CB14844418
- Molecular Formula:
- C26H30N2O4
- Molecular Weight:
- 434.53
- MDL Number:
- MOL File:
- 1352138-54-5.mol
| Boiling point | 584.6±50.0 °C(Predicted) |
|---|---|
| Density | 1.165±0.06 g/cm3(Predicted) |
| storage temp. | -20°C (des.) |
| solubility | Soluble in DMSO (up to 30 mg/ml). |
| pka | 9.17±0.10(Predicted) |
| form | oil |
| color | Light brown |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
(S)-PBMC (PBMC) price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | CEC13854 | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-carbamic acid (1S)-1-phenylethyl ester | 1352138-54-5 | 5mg | $250 | 2026-06-04 | Buy |
| Biosynth | CEC13854 | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-carbamic acid (1S)-1-phenylethyl ester | 1352138-54-5 | 10mg | $250 | 2026-06-04 | Buy |
| Biosynth | CEC13854 | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-carbamic acid (1S)-1-phenylethyl ester | 1352138-54-5 | 25mg | $370 | 2026-06-04 | Buy |
| Biosynth | CEC13854 | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-carbamic acid (1S)-1-phenylethyl ester | 1352138-54-5 | 50mg | $592 | 2026-06-04 | Buy |
| Biosynth | CEC13854 | N-(2-Aminoethyl)-N-[[3-methoxy-4-(phenylmethoxy)phenyl]methyl]-carbamic acid (1S)-1-phenylethyl ester | 1352138-54-5 | 100mg | $948 | 2026-06-04 | Buy |
(S)-PBMC (PBMC) Chemical Properties,Uses,Production
Description
PBMC (1352138-54-5) is a potent and selective blocker of TRPM8 channels. PBMC blocks both chemical and thermal activation of TRPM8.1Reverses the menthol and cold-induced facilitation of the micturition reflex.2PBMC represents a new lead for analgesic drugs based on blocking TRPM8.3
References
[1] WENDY M KNOWLTON. Pharmacological blockade of TRPM8 ion channels alters cold and cold pain responses in mice.[J]. PLoS ONE, 2011: e25894. DOI:10.1371/journal.pone.0025894
[2] JENNIFER C. GARDINER . The role of TRPM8 in the Guinea-pig bladder-cooling reflex investigated using a novel TRPM8 antagonist[J]. European journal of pharmacology, 2014, 740: Pages 398-409. DOI:10.1016/j.ejphar.2014.07.022
[3] KINGA SAŁAT Tadeusz L Andrzej Moniczewski. Transient receptor potential channels - emerging novel drug targets for the treatment of pain.[J]. Current medicinal chemistry, 2013, 20 11: 1409-1436. DOI:10.2174/09298673113209990107
(S)-PBMC (PBMC) Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-PBMC (PBMC) Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Biosynth Biological Technology (Suzhou) Co Ltd | -- | sales@biosynth.com | China | 6032 | 58 |
| Focus Biomolecules | -- | sales@focusbiomolecules.com | United States | 1282 | 58 |
| Supplier | Advantage |
|---|---|
| Biosynth Biological Technology (Suzhou) Co Ltd | 58 |
| Focus Biomolecules | 58 |
