Drofenine hydrochloride
- CAS No.
- 548-66-3
- Chemical Name:
- Drofenine hydrochloride
- Synonyms
- it-19;trasentinh;DrofeninHCl;DROFENINE HCL;cyclovegantine;cycloadiphenine;hexahydroadiphenine;Drofeninhydrochlorid;LABOTEST-BB LT00244841;cyclospasmol(tempelhof)
- CBNumber:
- CB1496239
- Molecular Formula:
- C20H32ClNO2
- Molecular Weight:
- 353.93
- MDL Number:
- MFCD00034983
- MOL File:
- 548-66-3.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Melting point | 145-147° |
|---|---|
| storage temp. | 2-8°C |
| solubility | Acetonitrile (Slightly), Chloroform (Slightly), DMSO (Slightly) |
| form | Solid |
| color | White to Off-White |
| FDA UNII | MVB31OPW05 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|---|---|
| Signal word | Warning |
| Hazard statements | H332-H302-H411 |
| Precautionary statements | P264-P270-P301+P312-P330-P501-P261-P271-P304+P340-P312 |
| WGK Germany | 2 |
| RTECS | GU6825000 |
| Toxicity | LD50 i.v. in mice: 65.6 mg/kg (Fleisch) |
Drofenine hydrochloride price More Price(16)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 43153 | Drofenine (hydrochloride) ≥98% | 548-66-3 | 10mg | $98 | 2026-04-30 | Buy |
| Cayman Chemical | 43153 | Drofenine (hydrochloride) ≥98% | 548-66-3 | 25mg | $208 | 2026-04-30 | Buy |
| Cayman Chemical | 43153 | Drofenine (hydrochloride) ≥98% | 548-66-3 | 50mg | $258 | 2026-04-30 | Buy |
| Cayman Chemical | 43153 | Drofenine (hydrochloride) ≥98% | 548-66-3 | 100mg | $686 | 2026-04-30 | Buy |
| Biosynth | AAA54866 | Drofenine hydrochloride | 548-66-3 | 0.1g | $900 | 2026-06-04 | Buy |
Drofenine hydrochloride Chemical Properties,Uses,Production
Originator
Trasentine A,Ciba
Uses
Spasmolytic
Uses
Drofenine is a widely used anticholinergic drug. It acts on smooth muscle to stop muscle spasms.
Manufacturing Process
17.4 parts of diphenylacetic acid 2-(diethylamino)ethyl ester were solved in
200 parts of acetic acid and hydrogenated over platinum catalyst. After the
calculated volume of hydrogen was passed, the catalyst was filtered off and
the solvent was removed to dryness. Ether, water and a potassium carbonate
solution were added to the remaining oil and were thoroughly shaken. The
ether layer was washed with water and dried over potassium carbonate. The
solvent was removed, the remaining oil was distilled in vacuum to give 2-
(diethylamino)ethyl α-phenylcyclohexaneacetate; BP 150°-160°C/0.2 mm Hg.
In practice it is usually used as hydrochloride.
Therapeutic Function
Spasmolytic
IC 50
BChE
Drofenine hydrochloride Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 18930552037 | 3bsc@sina.com | China | 15813 | 69 |
| S.Z. PhyStandard Bio-Tech. Co., Ltd. | 0755-83725681-603 | China | 4484 | 50 | |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Shanghai Chaolan Chemical Technology Center | QQ：65489617 13301690235 | Sales@ATKchemical.com | China | 9699 | 58 |
| Beijing Solarbio Science & Tecnology Co., Ltd. | 17801761073 18101056239 | 3193328036@qq.com | China | 28150 | 68 |
| Musechem | +1-800-259-7612 | info@musechem.com | United States | 4648 | 60 |
| Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd. | 027-51831887 15337167856 | hubeixinyuanshun@163.com | China | 10272 | 58 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 | sales@rrkchem.com | China | 57336 | 58 |
View Lastest Price from Drofenine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Drofenine hydrochloride
548-66-3
|
$58.00-82.00 | 99.53% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Drofenine hydrochloride
548-66-3
|
$58.00-82.00 | 99.53% | 10g | TargetMol Chemicals Inc. | ||
 |
2026-07-27 | Drofenine hydrochloride
548-66-3
|
$58.00-82.00 | 99.53% | 10g | TargetMol Chemicals Inc. |
-
- Drofenine hydrochloride
548-66-3
- $58.00-82.00
- 99.53%
- TargetMol Chemicals Inc.
-
- Drofenine hydrochloride
548-66-3
- $58.00-82.00
- 99.53%
- TargetMol Chemicals Inc.
-
- Drofenine hydrochloride
548-66-3
- $58.00-82.00
- 99.53%
- TargetMol Chemicals Inc.
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