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2-Amino-5-methoxypyrimidine

2-Amino-5-methoxypyrimidine Structure
2-Amino-5-methoxypyrimidine structure
CAS No.
13418-77-4
Chemical Name:
2-Amino-5-methoxypyrimidine
Synonyms
5-Methoxy-2-pyrimidinamine;2-Amino-5-methoxypyrimidine;5-Methoxypyrimidin-2-ylamine;2-Pyrimidinamine, 5-methoxy-;2-Amino-5-methoxypyrimidine,97%;2-Pyrimidinamine, 5-methoxy- (9CI);2-AMINO-5-METHOXYPYRIMIDINE ISO 9001：2015 REACH
CBNumber:
CB1506655
Molecular Formula:
C5H7N3O
Molecular Weight:
125.13
MDL Number:
MFCD00187864
MOL File:
13418-77-4.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:49:17
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2-Amino-5-methoxypyrimidine Properties

Melting point 86-88°C
Boiling point 313℃
Density 1.224
Flash point 143℃
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility Chloroform, Methanol
pka 3.62±0.10(Predicted)
form Powder
color Off-white
Sensitive Air Sensitive
CAS DataBase Reference 13418-77-4

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  29335990
NFPA 704
0
2 0

2-Amino-5-methoxypyrimidine price More Price(48)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC TRC-A611958-5G 2-Amino-5-methoxypyrimidine 13418-77-4 5g $1515 2026-06-03 Buy
TRC TRC-A611958-500MG 2-Amino-5-methoxypyrimidine 13418-77-4 500mg $193 2026-06-03 Buy
Apolloscientific OR54119 2-Amino-5-methoxypyrimidine 97% 13418-77-4 100mg $21 2026-06-04 Buy
Apolloscientific OR54119 2-Amino-5-methoxypyrimidine 97% 13418-77-4 250mg $24 2026-06-04 Buy
Apolloscientific OR54119 2-Amino-5-methoxypyrimidine 97% 13418-77-4 1g $25 2026-06-04 Buy
Product number Packaging Price Buy
TRC-A611958-5G 5g $1515 Buy
TRC-A611958-500MG 500mg $193 Buy
OR54119 100mg $21 Buy
OR54119 250mg $24 Buy
OR54119 1g $25 Buy

2-Amino-5-methoxypyrimidine Chemical Properties,Uses,Production

Chemical Properties

Yellow to Tan Solid

Synthesis

2-Chloro-5-methoxypyrimidine

22536-65-8

2-AMINO-5-METHOXYPYRIMIDINE

13418-77-4

General procedure for the synthesis of 2-amino-5-methoxypyrimidine using 2-chloro-5-methoxypyrimidine as starting material: 2-chloro-5-methoxypyrimidine (0.817 g, 5.65 mmol) and 25% aqueous ammonia solution were added to a microwave reaction vessel. The reaction vessel was sealed and the reaction was heated at 150 °C for 3 hours. After completion of the reaction, the mixture was evaporated to dryness. The resulting crude product was dissolved in dichloromethane/methanol (1:1, v/v) solvent mixture and loaded on silica gel. Purification by fast column chromatography (eluent: 50-100% ethyl acetate in heptane solution with gradient elution) afforded 2-amino-5-methoxypyrimidine as colorless crystals (386 mg, 55% yield).1H NMR (400 MHz, DMSO-d6) δ 8.02 (s, 1H), 6.06 (br s, 1H), 3.71 (s, 3H).

References

[1] Patent: WO2008/141239, 2008, A1. Location in patent: Page/Page column 54
[2] Bioorganic and Medicinal Chemistry Letters, 2017, vol. 27, # 5, p. 1261 - 1266

2-Amino-5-methoxypyrimidine Preparation Products And Raw materials

Raw materials

Guanidine nitrate 2-Chloro-5-methoxypyrimidine N,N-Dimethylformamide 1,1,2-Trimethoxyethane Ammonia

Preparation Products

2-Amino-5-methoxypyrimidine Suppliers

Global( 127)Suppliers
Supplier Tel Email Country ProdList Advantage
J & K SCIENTIFIC LTD. 18210857532 18210857532 jkinfo@jkchemical.com China 96815 76
PharmaBlock Sciences (Nanjing),Inc. 025-86918202 4000255188 sales@pharmablock.com China 5000 55
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42917 64
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32273 50
Shanghai Feibo Chemical Technology Co., Ltd 021-58955608,2250286 15921236618 blinkzeng@gmail.com China 522 62
Shandong Xiya Chemical Co., Ltd 13355009207 13355009207 3007715519@qq.com China 18722 57
ZhengZhou HuaWen Chemical Co.Ltd 0370-2785118 17550508557 675141927@qq.com China 3201 55
Chengdu Forest Science and Technology Development Co., Ltd. 18030648795 18030648795 sales@cdforestchem.com China 1997 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9336 55
Supplier Advantage
J & K SCIENTIFIC LTD. 76
PharmaBlock Sciences (Nanjing),Inc. 55
Pure Chemistry Scientific Inc. 62
Shanghai Hanhong Scientific Co.,Ltd. 64
Chemsky（shanghai）International Co.,Ltd. 50
Shanghai Feibo Chemical Technology Co., Ltd 62
Shandong Xiya Chemical Co., Ltd 57
ZhengZhou HuaWen Chemical Co.Ltd 55
Chengdu Forest Science and Technology Development Co., Ltd. 58
Shanghai Jian Chao Chemical Technology Co., Ltd. 55

View Lastest Price from 2-Amino-5-methoxypyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
5-methoxypyrimidin-2-amine pictures 2025-06-25 5-methoxypyrimidin-2-amine
13418-77-4
 $1.10 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2-AMINO-5-METHOXYPYRIMIDINE pictures 2019-07-06 2-AMINO-5-METHOXYPYRIMIDINE
13418-77-4
 $10.00 1KG 99% 100 Career Henan Chemical Co

2-Amino-5-methoxypyrimidine Spectrum

2-AMINO-5-METHOXYPYRIMIDINE(13418-77-4)1HNMR

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5-Methoxypyrimidin-2-ylamine 5-Methoxy-2-pyrimidinamine 2-Pyrimidinamine, 5-methoxy- (9CI) 2-Pyrimidinamine, 5-methoxy- 2-Amino-5-methoxypyrimidine,97% 2-AMINO-5-METHOXYPYRIMIDINE ISO 9001：2015 REACH 2-Amino-5-methoxypyrimidine 13418-77-4 Heterocycle-Pyrimidine series PYRIMIDINE Heterocyclic Compounds Bases & Related Reagents Heterocycles Nucleotides