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ChemicalBook >> CAS DataBase List >>6-amino-4-methoxy analogue of ZSTK474 (Compound 10w)

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w)

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) Structure
6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) structure
CAS No.
1336890-05-1
Chemical Name:
6-amino-4-methoxy analogue of ZSTK474 (Compound 10w)
Synonyms
Compound 10w;6-amino-4-methoxy analogue of ZSTK474 (Compound 10w);1H-Benzimidazol-6-amine, 2-(difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-methoxy-
CBNumber:
CB15544810
Molecular Formula:
C20H24F2N8O3
Molecular Weight:
462.45
MDL Number:
MOL File:
1336890-05-1.mol
MSDS File:
SDS
Last updated:2026-06-12 17:47:27
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6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) Properties

storage temp. Store at -20°C
solubility DMSO: 46 mg/mL (99.47 mM);Ethanol: Insoluble
Water Solubility Water: Insoluble

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-1096737 PI3K-IN-54 1336890-05-1 5mg $415 2026-06-04 Buy
aablocks AA024CZY Compound 10w 1336890-05-1 1mg $66 2026-06-01 Buy
aablocks AA024CZY Compound 10w 1336890-05-1 5mg $132 2026-06-01 Buy
aablocks AA024CZY Compound 10w 1336890-05-1 10mg $179 2026-06-01 Buy
aablocks AA024CZY Compound 10w 1336890-05-1 25mg $298 2026-06-01 Buy
Product number Packaging Price Buy
CS-1096737 5mg $415 Buy
AA024CZY 1mg $66 Buy
AA024CZY 5mg $132 Buy
AA024CZY 10mg $179 Buy
AA024CZY 25mg $298 Buy

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) Chemical Properties, Uses, Production

Uses

PI3K-IN-54 (compound 10w) is a pan-PI3K inhibitor. The IC50 values of PI3K-IN-54 for p110α, p110β, and p110δ are 0.22 nM, 1.4 nM, and 0.38 nM, respectively. PI3K-IN-54 can be used in cancer research[1].

Biological Activity

Compound 10w, a substituted pyrazolo [1,5-a] pyrimidine amide derivative, shows good anticancer activity against HeLa cell line, with IC50 of less than 10 μM against HeLa cell.

IC 50

p110α: 0.22 nM (IC50); p110β: 1.4 nM (IC50); p110δ: 0.38 nM (IC50)

References

[1] Kumar AKA, et al. Medicinal Chemistry Research. 2017; 26, 714-744.

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) Preparation Products And Raw materials

Raw materials

Preparation Products

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) Suppliers

Global Suppliers ( 11)
Supplier Tel Email Country ProdList Advantage
Guangzhou Isun Pharmaceutical Co., Ltd 020-39119399 18927568969 isunpharm@qq.com China 4773 55
Guangzhou Tomums Life Science Co., Ltd. 020-31155029 18902330969 sales@tomums.cn China 4688 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Nantong Hi-Future Biotechnology Co., Ltd +86-0513; 18051384581 sales@chemhifuture.com China 3075 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 18915873328 18915873328 sales@xianglongpharm.com China 11049 58
Shanghai Amole Biotechnology Co., Ltd. 13370042665 18916960931 2596183085@qq.com China 17234 58
Nantong HI-FUTURE Biology Co., Ltd. +86-18051384581 sales@chemhifuture.com China 3123 58
Supplier Advantage
Guangzhou Isun Pharmaceutical Co., Ltd 55
Guangzhou Tomums Life Science Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nantong Hi-Future Biotechnology Co., Ltd 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
Changzhou Xianglong Pharmaceutical Technology Co., Ltd., 58
Shanghai Amole Biotechnology Co., Ltd. 58
Nantong HI-FUTURE Biology Co., Ltd. 58

View Latest Price from 6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
PI3K-IN-54 pictures 2026-06-12 PI3K-IN-54
1336890-05-1
 $57.00-198.00 98.15% 10g TargetMol Chemicals Inc.
  • PI3K-IN-54 pictures
  • PI3K-IN-54
    1336890-05-1
  • $57.00-198.00
  • 98.15%
  • TargetMol Chemicals Inc.

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) Spectrum

6-amino-4-methoxy analogue of ZSTK474 (Compound 10w)(1336890-05-1)1HNMR

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6-amino-4-methoxy analogue of ZSTK474 (Compound 10w) 1H-Benzimidazol-6-amine, 2-(difluoromethyl)-1-(4,6-di-4-morpholinyl-1,3,5-triazin-2-yl)-4-methoxy- Compound 10w 1336890-05-1 C20H24F2N8O3