Benzyl cis-4-aminocyclohexylcarbamate
- CAS No.
- 149423-70-1
- Chemical Name:
- Benzyl cis-4-aminocyclohexylcarbamate
- Synonyms
- Benzyl (cis-4-aminocyclohexyl);cis-N-Cbz-1,4-cyclohexanediaMine;N-Cbz-cis-1,4-cyclohexanediamine;CIS-1-N-CBZ-1,4-CYCLOHEXYLDIAMINE;1-N-CBZ-CIS-1,4-CYCLOHEXYLDIAMINE;1-N-CBZ-cis-1,4-cyclohexanediamine;Trans-1N-Cbz-cyclohexane-1,4-diaMine;Benzyl cis-4-aminocyclohexylcarbamate;benzyl (1s,4s)-4-aminocyclohexylcarbamate;cis-4-(Benzyloxycarbonylamino)cyclohexylamine
- CBNumber:
- CB1691616
- Molecular Formula:
- C14H20N2O2
- Molecular Weight:
- 248.32
- MDL Number:
- MFCD06657668
- MOL File:
- 149423-70-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P280-P302+P352-P362+P364 |
| HS Code | 2924297099 |
Benzyl cis-4-aminocyclohexylcarbamate price More Price(46)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 270426 | 1-N-Z-cis-1,4-cyclohexyldiamine Asreported | 149423-70-1 | 50mg | $337 | 2026-06-03 | Buy |
| Usbiological | 270426 | 1-N-Z-cis-1,4-cyclohexyldiamine Asreported | 149423-70-1 | 100mg | $462 | 2026-06-03 | Buy |
| Usbiological | 270426 | 1-N-Z-cis-1,4-cyclohexyldiamine Asreported | 149423-70-1 | 250mg | $566 | 2026-06-03 | Buy |
| Usbiological | 270426 | 1-N-Z-cis-1,4-cyclohexyldiamine Asreported | 149423-70-1 | 500mg | $744 | 2026-06-03 | Buy |
| Usbiological | 270426 | 1-N-Z-cis-1,4-cyclohexyldiamine Asreported | 149423-70-1 | 1g | $1175 | 2026-06-03 | Buy |
Benzyl cis-4-aminocyclohexylcarbamate Chemical Properties, Uses, Production
Synthesis
![Carbamic acid, N-[cis-4-[[(1,1-dimethylethoxy)carbonyl]amino]cyclohexyl]-, phenylmethyl ester](/CAS/20210305/GIF/509143-03-7.gif)
509143-03-7
149423-70-1
Step B: Synthesis of cis-(4-amino-cyclohexyl)-carbamic acid benzyl ester. To a solution of cis-(4-tert-butoxycarbonylamino-cyclohexyl)-carbamic acid benzyl ester (6.2 g, 0.018 mol) in dichloromethane (40 mL) was added trifluoroacetic acid (2.7 mL, 0.36 mol). The reaction mixture was stirred at room temperature for 4 hours. Upon completion of the reaction, the excess solvent was removed by rotary evaporation and the resulting oil was dissolved in dichloromethane (30 mL). The organic layer was extracted with dilute aqueous sodium hydroxide/aqueous sodium bicarbonate solution (30 mL). The aqueous layer was back-extracted twice with dichloromethane, and the organic layers were combined, dried over anhydrous magnesium sulfate, and concentrated to give cis-(4-amino-cyclohexyl)-carbamic acid benzyl ester (4.3 g, 97%) as a colorless oil. The product was used directly in the next reaction without further purification.ESI MS m/z 249.2 [M + H]+.
References
[1] Patent: EP1464335, 2004, A2. Location in patent: Page/Page column 293
Benzyl cis-4-aminocyclohexylcarbamate Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| J & K SCIENTIFIC LTD. | 18210857532 18210857532 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Alfa Aesar | 400-6106006 | saleschina@alfa-asia.com | China | 30103 | 84 |
| Capot Chemical Co., Ltd | +86 (0) 571 85 58 67 18 | China | 18187 | 66 | |
| Tetranov Biopharm | 13526569071 | sales@leadmedpharm.com | China | 7881 | 64 |
| Shanghai Sunway Pharmaceutical Technology Co., Ltd | 13761987713 | hxzheng@sunwaypharm.cn | China | 8663 | 57 |
| Chengdu HappySyn Pharmaceutical Technology Co., Ltd. | 85114309 18982182443 | yangli@happysyn.com | China | 2297 | 55 |
| Chengdu Forest Science and Technology Development Co., Ltd. | 18030648795 18030648795 | sales@cdforestchem.com | China | 1998 | 58 |
| Nanjing Norris-Pharm Technology Co., Ltd | 13901585132 | sales@norris-pharm.com | China | 8869 | 55 |
| 9ding chemical ( Shanghai) Limited | 4009209199 | sales@9dingchem.com | China | 18201 | 56 |
| Shanghai Yolne Chemical Co., Ltd. | 021-62960152 | 934678158@qq.com | China | 9886 | 55 |
