4-IODO-7-AZAINDOLE
- CAS No.
- 319474-34-5
- Chemical Name:
- 4-IODO-7-AZAINDOLE
- Synonyms
- 4-IODO-7-AZAINDOLE;4-IODO-1H-PYRROLO[2,3-B]PYRIDINE;1H-Pyrrolo[2,3-b]pyridine, 4-iodo-
- CBNumber:
- CB1737396
- Molecular Formula:
- C7H5IN2
- Molecular Weight:
- 244.03
- MDL Number:
- MFCD08272234
- MOL File:
- 319474-34-5.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 4-Iodo-1H-pyrrolo[2,3-b]pyridine Aldrich | ADE000928 | 1g | $870 |
| 4-Iodo-1H-pyrrolo[2,3-b]pyridine | 026227 | 100.00mg | $237 |
| 4-Iodo-7-azaindole 97.0% | I7530 | 1g | $33 |
| 4-Iodo-7-azaindole 97.0% | I7530 | 5g | $90 |
| 4-Iodo-7-azaindole 97.0% | I7530 | 10g | $100 |
| More product size | |||
| Density | 2.082 |
|---|---|
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| form | solid |
| pka | 13.08±0.40(Predicted) |
| Appearance | Light brown to yellow Solid |
| InChI | InChI=1S/C7H5IN2/c8-6-2-4-10-7-5(6)1-3-9-7/h1-4H,(H,9,10) |
| InChIKey | PCHGYPNRADCIKG-UHFFFAOYSA-N |
| SMILES | C12NC=CC1=C(I)C=CN=2 |
| CAS DataBase Reference | 319474-34-5 |
| UNSPSC Code | 12352200 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H302-H315-H318-H335 |
| Precautionary statements | P261-P264-P280-P301+P312-P302+P352-P305+P351+P338 |
| target organs | Respiratory system |
| Hazard Codes | Xi,Xn |
| Risk Statements | 22-37/38-41 |
| Safety Statements | 26-39 |
| WGK Germany | 3 |
| HazardClass | IRRITANT |
| Storage Class | 11 - Combustible Solids |
| Hazard Classifications | Acute Tox. 4 Oral Eye Dam. 1 Skin Irrit. 2 STOT SE 3 |
4-IODO-7-AZAINDOLE price More Price(20)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | ADE000928 | 4-Iodo-1H-pyrrolo[2,3-b]pyridine Aldrich | 319474-34-5 | 1g | $870 | 2026-04-30 | Buy |
| Matrix Scientific | 026227 | 4-Iodo-1H-pyrrolo[2,3-b]pyridine | 319474-34-5 | 100.00mg | $237 | 2026-05-18 | Buy |
| Synthonix | I7530 | 4-Iodo-7-azaindole 97.0% | 319474-34-5 | 1g | $33 | 2026-05-06 | Buy |
| Synthonix | I7530 | 4-Iodo-7-azaindole 97.0% | 319474-34-5 | 5g | $90 | 2026-05-06 | Buy |
| Synthonix | I7530 | 4-Iodo-7-azaindole 97.0% | 319474-34-5 | 10g | $100 | 2026-05-06 | Buy |
4-IODO-7-AZAINDOLE Chemical Properties,Uses,Production
Synthesis
55052-28-3
319474-34-5
Part 2: Synthesis of 4-iodo-1H-pyrrolo[2,3-b]pyridine: To a mixture of 4-chloro-1H-pyrrolo[2,3-b]pyridine (12.9 g, 84.3 mmol) and NaI (40 g, 168 mmol) in acetonitrile (150 mL) was slowly added acetyl chloride (12.6 mL, 176 mmol). The reaction mixture was stirred at 80 °C for 4 days, followed by removal of excess acetonitrile by distillation under reduced pressure. To the residue was added 300 mL of 10% K2CO3 (aqueous solution) and extracted with CH2Cl2 (3 x 100 mL). The combined organic phases were washed sequentially with 10% sodium bisulfite (aqueous) and saturated brine, dried over anhydrous sodium sulfate and concentrated under reduced pressure to give the crude product (22.2 g). The crude product was dissolved in THF (150 mL) and 1 M NaOH (100 mL) was added. The mixture was stirred at room temperature for 2 h. The solvent was subsequently evaporated under reduced pressure, diluted with water and extracted with CH2Cl2. The organic phase was washed with saturated saline, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting brown solid was purified by silica gel column chromatography and recrystallized with acetonitrile to give pure 4-iodo-1H-pyrrolo[2,3-b]pyridine (9.75 g, 48% yield). Mass spectrum (ES+): 245 [MH+].
References
[1] Journal of Medicinal Chemistry, 2018,
[2] Tetrahedron Letters, 2007, vol. 48, # 9, p. 1527 - 1529
[3] Patent: US2004/186124, 2004, A1. Location in patent: Page/Page column 14
[4] Patent: US2011/282056, 2011, A1. Location in patent: Page/Page column 16
[5] Patent: WO2014/121883, 2014, A1. Location in patent: Page/Page column 54
4-IODO-7-AZAINDOLE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Daken Advanced Materials Co.,Ltd | +86-2158073036 | info@dakenam.com | China | 13901 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 | act@arborchemical.com | CHINA | 904 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29794 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21142 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-0519-85551759 +8613506123987 | marketing1@neostarunited.com | China | 8828 | 58 |
| NINGBOBENKANGJS PHARMTECHCO., LTD | +8615990591583 15990591583 | CHINA | 2029 | 58 | |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52705 | 58 |
| CR Corporation Limited | +8613062833949 | fred.wen@crcorporation.cn | China | 8645 | 58 |
View Lastest Price from 4-IODO-7-AZAINDOLE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-05 | 4-IODO-7-AZAINDOLE
319474-34-5
|
US $1.00 / KG | 1KG | 99% | 1kg-1000kg | Career Henan Chemical Co |
-
- 4-IODO-7-AZAINDOLE
319474-34-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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