BENZYL N-HYDROXYCARBAMATE
- CAS No.
- 3426-71-9
- Chemical Name:
- BENZYL N-HYDROXYCARBAMATE
- Synonyms
- Benzyl hydroxycarbamate;Z-HNOH;Z-NHOH;Cbz-NH-OH;N-Z-HYDROXYLAMINE;N-CBZ-HYDROXYLAMINE;Benyl N-hydroxycarbame;Benyl N-hydroxycarbaMate;BENZYL N-HYDROXYCARBAMATE;N-CARBOBENZOXYHYDROXYLAMINE
- CBNumber:
- CB1747920
- Molecular Formula:
- C8H9NO3
- Molecular Weight:
- 167.16
- MDL Number:
- MFCD00010642
- MOL File:
- 3426-71-9.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Product description | Number | Pack Size | Price |
| N-(Benzyloxycarbonyl)hydroxylamine 99% | 323276 | 5g | $47.7 |
| N-(Benzyloxycarbonyl)hydroxylamine 99% | 323276 | 25g | $194 |
| N-Carbobenzoxyhydroxylamine >97.0%(HPLC)(N) | C1557 | 5g | $57 |
| N-Carbobenzoxyhydroxylamine >97.0%(HPLC)(N) | C1557 | 25g | $190 |
| N-Benzyloxycarbonylhydroxylamine | TRC-B285915-5G | 5g | $282 |
| More product size | |||
| Melting point | 65-70 °C(lit.) |
|---|---|
| Boiling point | 295.73°C (rough estimate) |
| Density | 1.2917 (rough estimate) |
| refractive index | 1.5570 (estimate) |
| storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 9.20±0.23(Predicted) |
| color | White |
| Sensitive | Moisture Sensitive |
| BRN | 1074034 |
| InChI | InChI=1S/C8H9NO3/c10-8(9-11)12-6-7-4-2-1-3-5-7/h1-5,11H,6H2,(H,9,10) |
| InChIKey | PQBSPTAPCMSZAA-UHFFFAOYSA-N |
| SMILES | C(OCC1=CC=CC=C1)(=O)NO |
| CAS DataBase Reference | 3426-71-9(CAS DataBase Reference) |
| FDA UNII | AB5I7L0KH1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501 | |||||||||
| PPE | Eyeshields, Gloves, type N95 (US) | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | FB1600000 | |||||||||
| F | 21 | |||||||||
| HS Code | 29280000 | |||||||||
| Storage Class | 11 - Combustible Solids | |||||||||
| NFPA 704 |
|
BENZYL N-HYDROXYCARBAMATE price More Price(58)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 323276 | N-(Benzyloxycarbonyl)hydroxylamine 99% | 3426-71-9 | 5g | $47.7 | 2026-04-30 | Buy |
| Sigma-Aldrich | 323276 | N-(Benzyloxycarbonyl)hydroxylamine 99% | 3426-71-9 | 25g | $194 | 2026-04-30 | Buy |
| TCI Chemical | C1557 | N-Carbobenzoxyhydroxylamine >97.0%(HPLC)(N) | 3426-71-9 | 5g | $57 | 2026-04-30 | Buy |
| TCI Chemical | C1557 | N-Carbobenzoxyhydroxylamine >97.0%(HPLC)(N) | 3426-71-9 | 25g | $190 | 2026-04-30 | Buy |
| TRC | TRC-B285915-5G | N-Benzyloxycarbonylhydroxylamine | 3426-71-9 | 5g | $282 | 2026-06-03 | Buy |
BENZYL N-HYDROXYCARBAMATE Chemical Properties,Uses,Production
Chemical Properties
White Crystalline Solid
Uses
N-(Benzyloxycarbonyl)hydroxylamine reacts with cyclohepta-1,3-diene to produce 6-oxa-7-aza-bicyclo[3.2.2]non-8-ene-7-carboxylic acid benzyl ester.
Synthesis
501-53-1
3426-71-9
The general procedure for the synthesis of N-(benzylcarbonyloxy)hydroxylamine from benzyl chloroformate was as follows: 92.9 g (0.876 mol) of sodium carbonate (Na2CO3) and 300 mL of pure water were added to a 1 L three-necked flask, and the sodium carbonate was completely dissolved by mechanical stirring. Subsequently, 46.83 g (0.674 mol) of hydroxylamine hydrochloride was added, and 220 mL of dichloromethane solution containing 100 g (0.587 mol) of benzyl chloroformate was stirred and slowly added dropwise at room temperature for about 4 hours. After the dropwise addition, stirring was continued at room temperature for 1 h. Then 300 mL of pure water was added to separate the organic and aqueous layers. The aqueous layer was extracted with dichloromethane (150 mL each time, 3 times in total), and all the dichloromethane phases were combined, washed with 300 mL of saturated saline, and then dried with 20.0 g of anhydrous sodium sulfate. The dried solution was distilled under reduced pressure at 45 °C to remove the solvent to give the crude product I. The crude product was dissolved in 100 mL of dichloromethane, ensuring complete dissolution, then cooled to 0 °C in an ice-water bath and 300 mL of petroleum ether was added slowly and dropwise. The solution was crystallized at 0 °C for 1 h. The crystalline product was washed with pre-cooled mixed solvent (200 mL, petroleum ether: dichloromethane = 3:1, v/v) and dried at 35 °C under reduced pressure. Finally, it was stirred at 0 °C for 5 h to give 63.0 g of white powdery solid in 64% overall yield.
References
[1] Organic and Biomolecular Chemistry, 2009, vol. 7, # 21, p. 4531 - 4538
[2] Journal of Organic Chemistry, 2009, vol. 74, # 22, p. 8690 - 8694
[3] Journal of the American Chemical Society, 2010, vol. 132, # 37, p. 12862 - 12864
[4] Synthetic Communications, 2010, vol. 40, # 5, p. 642 - 646
[5] Helvetica Chimica Acta, 1991, vol. 74, # 8, p. 1653 - 1670
BENZYL N-HYDROXYCARBAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-029-81138252 +86-173 9270 1263 | 1057@dideu.com | China | 3955 | 58 |
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29626 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 | yuhh@hitechem.com | CHINA | 809 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32997 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29766 | 58 |
| Sichuan Jiaying Lai Technology Co.,LTD | 18716376478 | ycling@enlaibio.com | CHINA | 302 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19935 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63645 | 58 |
| CONIER CHEM AND PHARMA LIMITED | sales@conier.com | China | 49906 | 58 | |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9631 | 58 |
View Lastest Price from BENZYL N-HYDROXYCARBAMATE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-08-07 | BENZYL N-HYDROXYCARBAMATE
3426-71-9
|
1KG | 98% | 1000kgs | Shaanxi Dideu New Materials Co. Ltd | ||
 |
2024-07-25 | BENZYL N-HYDROXYCARBAMATE
3426-71-9
|
$1.00 | 1Kg | 98% | 20T | Shaanxi Dideu Medichem Co. Ltd | |
 |
2020-01-06 | Cbz-NH-OH
3426-71-9
|
$1.00 | 1g | 98% | 100KG | Sichuan Jiaying Lai Technology Co.,LTD |
-
- BENZYL N-HYDROXYCARBAMATE
3426-71-9
- $0.00
- 98%
- Shaanxi Dideu New Materials Co. Ltd
-
- BENZYL N-HYDROXYCARBAMATE
3426-71-9
- $1.00
- 98%
- Shaanxi Dideu Medichem Co. Ltd
-
- Cbz-NH-OH
3426-71-9
- $1.00
- 98%
- Sichuan Jiaying Lai Technology Co.,LTD
