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ChemicalBook >> CAS DataBase List >>(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one Structure
(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one structure
CAS No.
111821-58-0
Chemical Name:
(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one
Synonyms
(S)-(-)-HA-966;(S) ( ) HA 966,(S)()HA 966;S(-)-HA-966 S(-)-3-AMINO-1-HYDROX;(S)-3-Amino-1-hydroxy-2-pyrrolidinone;(3S)-3-Amino-1-hydroxy-2-pyrrolidinone;(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one;2-Pyrrolidinone, 3-amino-1-hydroxy-, (3S)-;(S)-(-)-3-Amino-1-hydroxypyrrolidine-2-one
CBNumber:
CB1775697
Molecular Formula:
C4H8N2O2
Molecular Weight:
116.12
MDL Number:
MFCD00078584
MOL File:
111821-58-0.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-09-12 18:50:05
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(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one Properties

Melting point 166℃
Boiling point 259℃
Density 1.436
Flash point 110℃
storage temp. Store at RT
pka 7.19±0.20(Predicted)
form Powder
color Off-white to light yellow
Water Solubility Soluble to 100 mM in water
FDA UNII 3C1G86U80C

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Usbiological 465120 S-(-)-HA-966 111821-58-0 1mg $340 2026-06-03 Buy
Usbiological 465120 S-(-)-HA-966 111821-58-0 2.5mg $523 2026-06-03 Buy
Usbiological 256562 S-(-)-HA-966 Asreported 111821-58-0 10mg $403 2026-06-03 Buy
Usbiological 256562 S-(-)-HA-966 Asreported 111821-58-0 50mg $1018 2026-06-03 Buy
ApexBio Technology B6244 (S)-(-)-HA-966 111821-58-0 10mg $164 2026-05-06 Buy
Product number Packaging Price Buy
465120 1mg $340 Buy
465120 2.5mg $523 Buy
256562 10mg $403 Buy
256562 50mg $1018 Buy
B6244 10mg $164 Buy

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one Chemical Properties,Uses,Production

Uses

(S)-(-)-HA-966 is an NMDA antagonist/partial agonist and is a potent sedative with ataxic action.

Biological Activity

Possesses potent sedative and ataxic action, probably through disruption of striatal dopaminergic mechanisms.

in vivo

(S)-(-)-HA 966 ((-)-HA 966; 3 and 5 mg/kg; i.p.) prevents restraint stress-induced dopamine utilization in both the medial prefrontal cortex and nucleus accumbens. (S)-(-)-HA 966 suppresses fear-induced behaviors: immobility and defecation[1].
(S)-(-)-HA 966 (3 mg/kg; i.p.) prevents locomotor sensitization without altering the acute motoric response elicited by cocaine[1].
(S)-(-)-HA 966 (5 mg/kg; i.p.) blocks acute cocaine-induced locomotion but resulted in sedation[1].

IC 50

NMDA Receptor

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one synthesis

111772-93-1
111821-58-0
Synthesis of (S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one from Carbamic acid, (1-hydroxy-2-oxo-3-pyrrolidinyl)-, phenylmethyl ester, (S)- (9CI)

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one Preparation Products And Raw materials

Raw materials

Carbamic acid, (1-hydroxy-2-oxo-3-pyrrolidinyl)-, phenylmethyl ester, (S)- (9CI)

Preparation Products

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 18930552037 3bsc@sina.com China 15813 69
China DongFan Chemical Co.,LTD 86-0571-85151182 China 5681 66
Atop-Pharma (Shanghai) Technology Co., Ltd. +86 (21) 5196-9732 China 996 57
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8435 60
Zhengzhou Huiju Chemical Co., Ltd. 0371-55900031 18137872243 3927209986@qq.com China 9997 55
BOC Sciences 16314854226; +8616314854226 inquiry@bocsci.com United States 19852 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
CONIER CHEM AND PHARMA LIMITED sales@conier.com China 49906 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8137 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 psaitong@jm-bio.com China 27626 58
Supplier Advantage
3B Pharmachem (Wuhan) International Co.,Ltd. 69
China DongFan Chemical Co.,LTD 66
Atop-Pharma (Shanghai) Technology Co., Ltd. 57
EMMX Biotechnology LLC 60
Zhengzhou Huiju Chemical Co., Ltd. 55
BOC Sciences 58
TargetMol Chemicals Inc. 58
CONIER CHEM AND PHARMA LIMITED 58
MedBioPharmaceutical Technology Inc 58
Beijing Jin Ming Biotechnology Co., Ltd. 58

View Lastest Price from (S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-(-)-HA 966 pictures 2026-05-11 (S)-(-)-HA 966
111821-58-0
 $837.00 10g TargetMol Chemicals Inc.

111821-58-0((S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one)Related Search:

(S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one (+/-)-3-Amino-1-hydroxy-2-pyrrolidone Amino acid hydroxamates glycine hydroxamate alpha-Pyridoin (R)-(+)-3-AMINO-1-HYDROXYPYRROLIDIN-2-ONE
(+/-)-HA-966 (S)-3-Aminopyrrolidine 3-AMINO-PYRROLIDIN-2-ONE

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(S)-(-)-HA-966 S(-)-HA-966 S(-)-3-AMINO-1-HYDROX (S)-(-)-3-Amino-1-hydroxypyrrolidine-2-one (3S)-3-Amino-1-hydroxy-2-pyrrolidinone (S)-3-Amino-1-hydroxy-2-pyrrolidinone 2-Pyrrolidinone, 3-amino-1-hydroxy-, (3S)- (S) ( ) HA 966,(S)()HA 966 (S)-(-)-3-Amino-1-hydroxypyrrolidin-2-one 111821-58-0 4H8N2O2 Glutamate receptor