Chinese Japanese Germany Korea
ChemicalBook >> CAS DataBase List >>1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl-

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl-

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- Structure
1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- structure
CAS No.
2414374-53-9
Chemical Name:
1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl-
Synonyms
RET-IN-3;RET-IN-3, 10 mM in DMSO;1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl-;N1-(3-(Benzo[d][1,3]dioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-N3,N3-dimethylpropane-1,3-diamine
CBNumber:
CB18097124
Molecular Formula:
C18H21N5O2
Molecular Weight:
339.39
MDL Number:
MOL File:
2414374-53-9.mol
MSDS File:
SDS
Last updated:2026-05-27 23:44:48
Request For Quotation

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- Properties

solubility DMSO: Sparingly soluble: 1-10 mg/mL
Ethanol: Sparingly soluble: 1-10 mg/mL
form Solid
color Off-white to light yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P280-P301+P312-P302+P352-P305+P351+P338

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 43193 RET-IN-3 ≥98% 2414374-53-9 5mg $297 2026-04-30 Buy
Cayman Chemical 43193 RET-IN-3 ≥98% 2414374-53-9 10mg $505 2026-04-30 Buy
Cayman Chemical 43193 RET-IN-3 ≥98% 2414374-53-9 25mg $891 2026-04-30 Buy
Cayman Chemical 43193 RET-IN-3 ≥98% 2414374-53-9 50mg $1485 2026-04-30 Buy
Biosynth PWD37453 RET-IN-3 2414374-53-9 10mg $573.7 2026-06-04 Buy
Product number Packaging Price Buy
43193 5mg $297 Buy
43193 10mg $505 Buy
43193 25mg $891 Buy
43193 50mg $1485 Buy
PWD37453 10mg $573.7 Buy

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- Chemical Properties, Uses, Production

Description

RET-IN-3 is a is a selective RETV804M kinase inhibitor.

Uses

RET-IN-3 (compound 34) is a selective RETV804M kinase inhibitor, with an IC50 of 19 nM[1].

References

[1] Rebecca Newton, et al. Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RET V804M Kinase. ACS Med Chem Lett. 2020 Feb 28;11(4):497-505. DOI:10.1021/acsmedchemlett.9b00615

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- Suppliers

Global Suppliers ( 17)
Supplier Tel Email Country ProdList Advantage
Shanghai Beckham Medical Technology Co., Ltd 13816613772 huahero21@sina.com China 2996 55
Shanghai YuanYe Biotechnology Co., Ltd. 15026964105 2881489226@qq.com China 89667 60
Shanghai Chaolan Chemical Technology Center QQ：65489617 13301690235 Sales@ATKchemical.com China 9699 58
Zhejiang Huida Biotech Co., LTD 0571-89903022 18679456698 zilong@hizyme.com China 8001 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
TargetMol Chemicals Inc. 4008200310 15002144251 marketing@tsbiochem.com China 24951 58
Aikon International Limited 17714375163 hywu@aikonchem.com China 9974 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 18100677375 sales@szzxbio.com China 1129 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 021-57520305 13795461237 zhuruyan@jskchem.com China 49221 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11963 58
Supplier Advantage
Shanghai Beckham Medical Technology Co., Ltd 55
Shanghai YuanYe Biotechnology Co., Ltd. 60
Shanghai Chaolan Chemical Technology Center 58
Zhejiang Huida Biotech Co., LTD 58
Bide Pharmatech Ltd. 58
TargetMol Chemicals Inc. 58
Aikon International Limited 58
Suzhou Zhixin Biotechnology Co., Ltd. 58
Shanghai Jieshikai Biotechnology Co. , Ltd. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- Spectrum

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl-(2414374-53-9)1HNMR

2414374-53-9 (1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl-) Related Search:

Pyrazolo[1,5-a]pyrimidine-5,7-diamine, 3-(3,4-dimethoxyphenyl)-N5-(1,2,2,6,6-pentamethyl-4-piperidinyl)-6-phenyl- 1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- 4-(3'-Hydroxyphenyl)amino-6,7-dimethoxyquinazoline, HCl 17,19-Metheno-1H,5H-cyclopent[5,6][1,4]oxazino[3,4-i]pyrazolo[4,3-f]pyrido[3,2-l][1,4,8,10]oxatriazacyclotridecin-14(11H)-one, 7-fluoro-2,3,3a,12,13,20a-hexahydro-11-methyl-, (3aS,11R,20aR)- 2-Pyridinecarboxamide, 4-[4-[[[[2-fluoro-5-[1,2,2,2-tetrafluoro-1-(trifluoromethyl)ethyl]phenyl]amino]carbonyl]amino]phenoxy]-N-methyl-
RET Extracellular Domain (human, recombinant)

1of2

1,3-Propanediamine, N3-[3-(1,3-benzodioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl]-N1,N1-dimethyl- RET-IN-3 N1-(3-(Benzo[d][1,3]dioxol-5-yl)pyrazolo[1,5-a]pyrimidin-5-yl)-N3,N3-dimethylpropane-1,3-diamine RET-IN-3, 10 mM in DMSO 2414374-53-9