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ChemicalBook >> CAS DataBase List >>Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Structure
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- structure
CAS No.
2305936-70-1
Chemical Name:
Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
Synonyms
OUN 36701;Poma-C?-COOH;Thalidomide-4-NH-C8-COOH;Pomalidomide 4'-alkylC8-acid;9-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino]nonanoic Acid;9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid;9-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]nonanoic acid;9-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}nonanoic acid;Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-
CBNumber:
CB18344509
Molecular Formula:
C22H27N3O6
Molecular Weight:
429.47
MDL Number:
MOL File:
2305936-70-1.mol
MSDS File:
SDS
TDS File:
TDS
Last updated:2026-05-11 16:31:51
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Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Properties

Boiling point 718.9±60.0 °C(Predicted)
Density 1.351±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
pka 4.78±0.10(Predicted)

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0142071 Pomalidomide 4'-alkylC8-acid 2305936-70-1 1mg $75 2026-06-04 Buy
ChemScene CS-0142071 Pomalidomide 4'-alkylC8-acid 2305936-70-1 5mg $186 2026-06-04 Buy
ChemScene CS-0142071 Pomalidomide 4'-alkylC8-acid 2305936-70-1 10mg $298 2026-06-04 Buy
ChemScene CS-0142071 Pomalidomide 4'-alkylC8-acid 2305936-70-1 25mg $531 2026-06-04 Buy
ChemScene CS-0142071 Pomalidomide 4'-alkylC8-acid 2305936-70-1 50mg $953 2026-06-04 Buy
Product number Packaging Price Buy
CS-0142071 1mg $75 Buy
CS-0142071 5mg $186 Buy
CS-0142071 10mg $298 Buy
CS-0142071 25mg $531 Buy
CS-0142071 50mg $953 Buy

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Chemical Properties, Uses, Production

Description

Pomalidomide C8-acid, also known as Pomalidomide 4'-alkylC8-acid and OUN36701, is a Pomalidomide-based cereblon ligand with a linker, which is a useful precursor for synthesis of PROTAC degraders. Targeted protein degradation (TPD) is an emerging therapeutic modality with the potential to tackle disease-causing proteins that have historically been highly challenging to target with conventional small molecules. PROTAC degraders are usually heterobifunctional small molecules consisting of two ligands joined by a linker: one ligand recruits and binds a protein of interest (POI) while the other recruits and binds an E3 ubiquitin ligase. Simultaneous binding of the POI and ligase by the PROTAC induces ubiquitylation of the POI and its subsequent degradation by the ubiquitin–proteasome system (UPS), after which the PROTAC is recycled to target another copy of the POI.ubiquitylation of the POI and its subsequent degradation by the ubiquitin–proteasome system (UPS), after which the PROTAC is recycled to target another copy of the POI.

Uses

Pomalidomide 4'-alkylC8-acid is an E3 ubiquitin ligase ligand-Linker conjugate containing Pomalidomide (HY-10984). Pomalidomide is a third-generation immunomodulator that acts like a molecular glue. Pomalidomide interacts with the E3 ligase cereblon to induce degradation of the essential Ikaros transcription factor[1].

storage

Store at -20°C

References

[1] Zhu YX, et al. Molecular mechanism of action of the immune-modulatory drugs, thalidomide, lenalidomide and pomalidomide in multiple myeloma. Leuk Lymphoma. 2013 Apr;54(4):683-7. DOI:10.3109/10428194.2012.728597

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Preparation Products And Raw materials

Raw materials

Preparation Products

Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Suppliers

Global Suppliers ( 23)
Supplier Tel Email Country ProdList Advantage
Daicel Chiral Technologies (China)CO.,LTD 021-50460086-9 15921403865 han_yajun@dctc.daicel.com China 7909 65
Chengdu Novel Biomedical Co., Ltd. 028-85255396 18302801538 cdnovell@163.com China 2445 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
TargetMol Chemicals Inc. +1-781-999-5354; +1-00000000000 marketing@targetmol.com United States 32431 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 025-86755008 17751752005 hszhang@bestfluorodrug.com China 2357 58
Shandong Territorial sea Biological Technology Co., LTD 15092083467 tangfenjiushililiang@leadhigh.com.cn China 2986 58
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9982 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2223443625@qq.com China 7998 58
Wuhan Augda Biotechnology Co., Ltd 15071299552 262933239@qq.com China 7201 58
Bide Pharmatech Ltd. 400-1647117 13681763483 product02@bidepharm.com China 59929 58
Supplier Advantage
Daicel Chiral Technologies (China)CO.,LTD 65
Chengdu Novel Biomedical Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
TargetMol Chemicals Inc. 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 58
Shandong Territorial sea Biological Technology Co., LTD 58
Zhengzhou convergence chemical co., LTD 58
Hubei Kele Fine Chemical Co., Ltd 58
Wuhan Augda Biotechnology Co., Ltd 58
Bide Pharmatech Ltd. 58

View Latest Price from Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide 4'-alkylC8-acid pictures 2026-05-11 Pomalidomide 4'-alkylC8-acid
2305936-70-1
 $758.00 10g TargetMol Chemicals Inc.

2305936-70-1 (Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-) Related Search:

Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Pomalidomide 4'-alkylC5-acid 4-((2-azidoethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione INDEX NAME NOT YET ASSIGNED
E3 ligase Ligand-Linker Conjugates 49 Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide Pomalidomide-C6-PEG3-butyl iodide POMALIDOMIDE-C9-CO2H 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl
E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3 Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride
Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-

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Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- OUN 36701 9-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)nonanoic acid Thalidomide-4-NH-C8-COOH 9-[[2-(2,6-Dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]amino]nonanoic Acid Poma-C?-COOH Pomalidomide 4'-alkylC8-acid 9-{[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]amino}nonanoic acid 9-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]nonanoic acid 2305936-70-1