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Pomalidomide-C6-PEG3-butyl iodide

Pomalidomide-C6-PEG3-butyl iodide Structure
Pomalidomide-C6-PEG3-butyl iodide structure
CAS No.
1835705-70-8
Chemical Name:
Pomalidomide-C6-PEG3-butyl iodide
Synonyms
Poma-6-2-2-6-I;Pomalidomide-6-2-2-6-I;Pomalidomide-C6-PEG3-butyl iodide;Pomalidomide-C6-PEG3-butyl iodide;N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-6-[2-[2-(6-iodohexoxy)ethoxy]ethoxy]hexanamide;N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-6-(2-{2-[(6-iodohexyl)oxy]ethoxy}ethoxy)hexanamide;Hexanamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-6-[2-[2-[(6-iodohexyl)oxy]ethoxy]ethoxy]-;N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-6-(2-(2-((6-iodohexyl)oxy)ethoxy)ethoxy)hexanamide, Crosslinker?E3 Ligase ligand conjugate, Pomalidomide-6-2-2-6-I, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB75430559
Molecular Formula:
C29H40IN3O8
Molecular Weight:
685.55
MDL Number:
MFCD32173805
MOL File:
1835705-70-8.mol
MSDS File:
SDS
Last updated:2026-01-13 11:26:45
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Pomalidomide-C6-PEG3-butyl iodide Properties

Boiling point 813.9±65.0 °C(Predicted)
Density 1.446±0.06 g/cm3(Predicted)
storage temp. 2-8°C
pka 10.69±0.40(Predicted)
form powder or crystals
InChIKey QZIUVZMTAVRENH-UHFFFAOYSA-N
SMILES ICCCCCCOCCOCCOCCCCCC(NC1=CC=CC2=C1C(N(C3CCC(NC3=O)=O)C2=O)=O)=O
UNSPSC Code 12352101
NACRES NA.22

SAFETY

Risk and Safety Statements

WGK Germany  WGK 3
Storage Class 11 - Combustible Solids

Pomalidomide-C6-PEG3-butyl iodide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 904708 Pomalidomide-C6-PEG3-butyl iodide ≥95% 1835705-70-8 50MG $493 2026-04-30 Buy
Iris Biotech GmbH PTC1700 Pomalidomid-C6-PEG3-butyl-I 1835705-70-8 50mg $567 2021-12-16 Buy
Product number Packaging Price Buy
904708 50MG $493 Buy
PTC1700 50mg $567 Buy

Pomalidomide-C6-PEG3-butyl iodide Chemical Properties, Uses, Production

Uses

Protein degrader builiding block Pomalidomide-C6-PEG3-butyl iodide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant iodoalkane for reactivity with a nucleophilic group on a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant iodo group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reactivity: sulfuryl reactive
reagent type: ligand-linker conjugate

Pomalidomide-C6-PEG3-butyl iodide Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-C6-PEG3-butyl iodide Suppliers

Global Suppliers ( 14)
Supplier Tel Email Country ProdList Advantage
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51389 80
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4229 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1644 58
Changsha Bono New Materials Technology Co., Ltd. 18191076804 asherw9@hotmail.com China 2373 58
Zhengzhou convergence chemical co., LTD 037155153829 18003835034 3897192574@qq.com China 9982 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 13417589054 trendseenbio@gmail.com China 9067 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 17634413542 1959525201@qq.com China 9011 58
Dipag (Weinan) Biotechnology Co., Ltd 15114901355 1002921772@qq.com China 190 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 15306536782 3839324846@qq.com China 149 58
Xian confluore Biological Technology Co., Ltd. +86-15680926068 1924344760@confluore.cn China 3000 58
Supplier Advantage
Sigma-Aldrich 80
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Changsha Bono New Materials Technology Co., Ltd. 58
Zhengzhou convergence chemical co., LTD 58
ShenZhen Trendseen Biological Technology Co.,Ltd. 58
Henan Mengtai Pharmaceutical Technology Co., Ltd 58
Dipag (Weinan) Biotechnology Co., Ltd 58
HANGZHOU LAURET BIOTECHOLOGY CO.,LTD 58
Xian confluore Biological Technology Co., Ltd. 58

View Latest Price from Pomalidomide-C6-PEG3-butyl iodide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-6-2-2-6-I pictures 2025-06-07 Pomalidomide-6-2-2-6-I
1835705-70-8
 100mg >95.00% 100mg Xian confluore Biological Technology Co., Ltd.

1835705-70-8 (Pomalidomide-C6-PEG3-butyl iodide) Related Search:

E3 ligase Ligand-Linker Conjugates 49 4-[(2-Aminoethyl)amino]-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl E3 ligase Ligand-Linker Conjugates 55 1H-Isoindole-1,3(2H)-dione, 4-[(2-aminoethyl)amino]-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1) Pomalidomide-6-2-2-6-N3
Pomalidomide-amido-C1-Br Pomalidomide-C6-NH2?hydrochloride Nonanoic acid, 9-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Octanoic acid, 8-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Pomalidomide-C6-PEG1-C3-PEG1-butyl iodide
POMALIDOMIDE-C9-CO2H Heptanoic acid, 7-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Butanoic acid, 4-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]- Pomalidomide 4'-alkylC5-acid Pomalidomide-PEG6-butyl iodide
Pomalidomide-PEG1-piperazine BI 3663 Pomalidomide-PEG2-butyl iodide

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Pomalidomide-C6-PEG3-butyl iodide Pomalidomide-6-2-2-6-I N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxo-isoindolin-4-yl]-6-[2-[2-(6-iodohexoxy)ethoxy]ethoxy]hexanamide Hexanamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-6-[2-[2-[(6-iodohexyl)oxy]ethoxy]ethoxy]- N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-6-(2-(2-((6-iodohexyl)oxy)ethoxy)ethoxy)hexanamide, Crosslinker?E3 Ligase ligand conjugate, Pomalidomide-6-2-2-6-I, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader Poma-6-2-2-6-I N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-6-(2-{2-[(6-iodohexyl)oxy]ethoxy}ethoxy)hexanamide Pomalidomide-C6-PEG3-butyl iodide 1835705-70-8